Research output per year
Research output per year
Description
These files are the first 10 eigenvectors arising after principle component analysis. An homology model of the extracellular domain of the receptor in complex with the extracellular domain of RAMP1 was generated and the minimised protein was placed centrally in a charge neutral cubic box (x=10nm) consisting of TIP3 water molecules, 150 mM NaCl and simulated for 1µs. The files consist of 99 snapshots. They may be viewed using VMD, available freely from the University of Illinois.
Funding: Maurice Wilkins Centre for Molecular Biodiscovery, Maurice and Phyllis Paykel Trust, University of Auckland doctoral scholarship, National Heart Foundation of New Zealand, National Institute of Health (R01GM104251), Wellcome Trust (091496), National Health and Medical Research Council of Australia (1061044, 1055134)
Funding: Maurice Wilkins Centre for Molecular Biodiscovery, Maurice and Phyllis Paykel Trust, University of Auckland doctoral scholarship, National Heart Foundation of New Zealand, National Institute of Health (R01GM104251), Wellcome Trust (091496), National Health and Medical Research Council of Australia (1061044, 1055134)
| Date made available | 21 Jul 2015 |
|---|---|
| Publisher | Aston Data Explorer |
| Date of data production | 2015 - |
Research output
- 1 Article
-
An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology
Gingell, J. J., Simms, J., Barwell, J., Poyner, D. R., Watkins, H. A., Pioszak, AA., Sexton, P. M. & Hay, D. L., 17 May 2016, In: Cell Discovery. 2, 16012.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
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Homology models of the extracellular domains of the calcitonin and amylin receptors, with or without bound amylin and CGRP
Poyner, D. (Creator) & Simms, J. (Creator), Aston Data Explorer, 31 Dec 2015
DOI: 10.17036/7aab1727-d526-4592-86db-e6a384bed10e, https://www.nature.com/articles/celldisc201612
Dataset