Cell & Tissue Biomedical Research

Research Output

2014

Blockade of interleukin-6 effects on cytokine profiles and macrophage activation after spinal cord injury in mice

Rodriguez Guerrero, A., Uchida, K., Nakajima, H., Watanabe, S., Nakamura, M., Okada, S., Johnson, W. E. B. & Baba, H., 31 Jan 2014, Neuroprotection and regeneration of the spinal cord. Uchida, K., Nakamura, M., Ozawa, H. & et al (eds.). Tokyo (JP): Springer, p. 203-212 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Can restricting calories help you to live longer?

Brown, J. E., 13 Mar 2014, In : Post Reproductive Health. 20, 1, p. 16-18 3 p.

Research output: Contribution to journalArticle

Open Access
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Cell-nonautonomous effects of dFOXO/DAF-16 in aging

Alic, N., Tullet, J. M., Niccoli, T., Broughton, S., Hoddinott, M. P., Slack, C., Gems, D. & Partridge, L., 27 Feb 2014, In : Cell Reports. 6, 4, p. 608-616 9 p.

Research output: Contribution to journalArticle

Open Access
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Cellular uptake of ribonuclease A-functionalised core-shell silica microspheres

Chimonides, G. F., Behrendt, J. M., Chundoo, E., Bland, C., Hine, A. V., Devitt, A., Nagel, D. A. & Sutherland, A. J., 14 Nov 2014, In : Journal of Materials Chemistry B. 2, 42, p. 7307-7315 9 p.

Research output: Contribution to journalArticle

Open Access
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Characterisation of ICAM-3 and extracellular vesicles in the clearance of apoptotic cells

Alghareeb, K., Nadella, V., Bland, C. E. & Devitt, A., 2014.

Research output: Contribution to conferencePoster

Open Access
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Combined use of bacteriophage K and a novel bacteriophage to reduce Staphylococcus aureus biofilm formation

Alves, D. R., Gaudion, A., Bean, J. E., Perez Esteban, P., Arnot, T. C., Harper, D. R., Kot, W., Hansen, L. H., Enright, M. C. & Jenkins, A. T. A., Nov 2014, In : Applied and Environmental Microbiology. 80, 21, p. 6694-703 10 p.

Research output: Contribution to journalArticle

Open Access
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Comparison of weight loss outcomes between obese patients with and without Type 2 diabetes attending a weight management focused structured educational group

Abernethy, G., Mann, V., John, R., Shakher, J., Bellary, S., Tahrani, A. A., Brown, A. C., Wright, A. & Davies, R., 31 Mar 2014, In : Diabetic Medicine. 31, s1, p. 7 1 p., A17 (P234).

Research output: Contribution to journalConference abstract

Cross-linking of collagen I by tissue transglutaminase provides a promising biomaterial for promoting bone healing

Fortunati, D., Chau, D. Y. S., Wang, Z., Collighan, R. J. & Griffin, M., 31 Jul 2014, In : Amino Acids. 46, 7, p. 1751-1761 11 p.

Research output: Contribution to journalArticle

Diabetes in the very elderly: need for an individualised approach

Bellary, S. & Oluwatoyin, A., 31 Mar 2014, In : Diabetic Medicine. 31, s1, p. 74 1 p., P155.

Research output: Contribution to journalConference abstract

Diabetes management in care homes: steps in the right direction?

Sloan, E. & Bellary, S., 31 Mar 2014, In : Diabetic Medicine. 31, s1, p. 164 1 p., P455.

Research output: Contribution to journalConference abstract

Does metabolic reprogramming underpin age-associated changes in T cell phenotype and function?

Torrão, R. C., Bennett, S. J., Brown, J. E. & Griffiths, H. R., Jun 2014, In : Free Radical Biology and Medicine. 71, p. 26–35 10 p.

Research output: Contribution to journalArticle

Open Access
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Effect of incorporating cholesterol into DDA:TDB liposomal adjuvants on Bilayer properties, biodistribution, and immune responses

Kaur, R., Henriksen-Lacey, M., Wilkhu, J., Devitt, A., Christensen, D. & Perrie, Y., 6 Jan 2014, In : Molecular Pharmaceutics. 11, 1, p. 197-207 11 p.

Research output: Contribution to journalArticle

Open Access

Effect of maternal protein restriction during pregnancy and postweaning high-fat feeding on diet-induced thermogenesis in adult mouse offspring

Sellayah, D., Dib, L., Anthony, F. W., Watkins, A. J., Fleming, T. P., Hanson, M. A. & Cagampang, F. R., 31 Oct 2014, In : European Journal of Clinical Nutrition. 53, 7, p. 1523-1531 9 p.

Research output: Contribution to journalArticle

Elevated serum free light chains predict cardiovascular events in type 2 diabetes

Bellary, S., Faint, J. M., Assi, L. K., Hutchison, C. A., Harding, S. J., Raymond, N. T. & Barnett, A. H., 31 Jul 2014, In : Diabetes Care. 37, 7, p. 2028-2030 3 p.

Research output: Contribution to journalArticle

Enhancement of the antimicrobial properties of bacteriophage-K via stabilization using oil-in-water nano-emulsions

Perez Esteban, P., Alves, D. R., Enright, M. C., Bean, J. E., Gaudion, A., Jenkins, A. T. A., Young, A. E. R. & Arnot, T. C., 2014, In : Biotechnology Progress. 30, 4, p. 932-944 13 p.

Research output: Contribution to journalArticle

Open Access
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Ethnic differences in health related quality of life for patients with type 2 diabetes

Jhita, T., Petrou, S., Gumber, A., Szczepura, A., Raymond, N. T. & Bellary, S., 5 Jun 2014, In : Health and Quality of Life Outcomes. 12, 10 p., 83.

Research output: Contribution to journalArticle

Open Access
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Gene therapy strategies for the treatment of spinal cord injury

Uchida, K., Nakajima, H., Guerrero, A. R., Johnson, W. E., El Masri, W. & Baba, H., 2014, In : Therapeutic Delivery. 5, 5, p. 591-607 17 p.

Research output: Contribution to journalArticle

Heparanase and COX-2 expression as predictors of lymph node metastasis in large, high-grade breast tumors

Gawthorpe, S., Brown, J. E., Arif, M., Nightingale, P., Nevill, A. & Carmichael, A. R., 30 Jun 2014, In : Anticancer Research. 34, 6, p. 2797-2800 4 p.

Research output: Contribution to journalArticle

Open Access
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High-throughput manufacturing of size-tuned liposomes by a new microfluidics method using enhanced statistical tools for characterization

Kastner, E., Kaur, R., Lowry, D., Moghaddam, B., Wilkinson, A. & Perrie, Y., 30 Dec 2014, In : International Journal of Pharmaceutics. 477, 1-2, p. 361-368 8 p.

Research output: Contribution to journalArticle

Open Access
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Homeostasis and function of regulatory T cells (Tregs) in vivo: lessons from TCR-transgenic Tregs

Attridge, K. & Walker, L. S. K., May 2014, In : Immunological Reviews. 259, 1, p. 23-39 17 p.

Research output: Contribution to journalReview article

Open Access
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Human aquaporins: regulators of transcellular water flow

Day, R. E., Kitchen, P., Owen, D., Bland, C., Marshall, L., Conner, A. C., Bill, R. M. & Conner, M. T., 1 May 2014, In : BBA - General Subjects. 1840, 5, p. 1492-1506

Research output: Contribution to journalArticle

Open Access
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Hypercholesterolaemia-induced oxidative stress at the blood-brain barrier

Dias, I. H. K., Polidori, M. C. & Griffiths, H. R., Aug 2014, In : Biochemical Society Transactions. 42, 4, p. 1001-1005 5 p.

Research output: Contribution to journalArticle

Open Access
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IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells

Attridge, K., Kenefeck, R., Wardzinski, L., Qureshi, O. S., Wang, C. J., Manzotti, C., Okkenhaug, K. & Walker, L. S. K., 1 Mar 2014, In : Journal of Immunology. 192, 5, p. 2195-2201 7 p.

Research output: Contribution to journalArticle

Importance of tissue transglutaminasenitrosylation in fibroblasts migration and MMPregulation

Kurt, I., Kiliç, A. N., Griffin, M. & Telci, D., 30 Sep 2014, In : FEBS journal. 281, Suppl.1, p. 528 1 p., TUE-295.

Research output: Contribution to journalConference abstract

Insulin therapy in people with type 2 diabetes: opportunities and challenges?

Home, P., Riddle, M., Cefalu, W. T., Bailey, C. J., Bretzel, R. G., del Prato, S., Leroith, D., Schernthaner, G., van Gaal, L. & Raz, I., Jun 2014, In : Diabetes Care. 37, 6, p. 1499-1508 10 p.

Research output: Contribution to journalArticle

Open Access
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Investigating buccal cell cultures to enhance in vitro assessment of transmucosal drug delivery

Iyrie, A., Russell, C., Bailey, C. J. & Mohammed, A., 2014, UKICRS Newsletter, p. 38-40 3 p.

Research output: Contribution to specialist publicationFeatured article

Open Access

Macrophage polarisation by fatty acids is PPARgamma-dependent

Pararasa, C., Bailey, C. & Griffiths, H., Oct 2014, In : Free Radical Biology and Medicine. 75, Suppl.1, p. S31-S32 2 p., P32.

Research output: Contribution to journalConference abstract

Mapping nitro-tyrosine modifications in fibrinogen by mass spectrometry as a biomarker for inflammatory disease

Meredith, S., Parekh, G., Towler, J., Schouten, J., Davis, P., Griffiths, H. & Spickett, C., Oct 2014, In : Free Radical Biology and Medicine. 75, Suppl.1, p. S50 1 p., P87.

Research output: Contribution to journalConference abstract

Open Access
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Metformin

Bailey, C. J., 5 Aug 2014, Therapy for diabetes mellitus and related disorders. Umpierrez, G. E. (ed.). 6th ed. Alexandria, VA (US), p. 341-358 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Metformin in patients with type 2 diabetes and kidney disease: a systematic review

Inzucchi, S. E., Lipska, K. J., Mayo, H., Bailey, C. J. & McGuire, D. K., 24 Dec 2014, In : JAMA: Journal of the American Medical Association. 312, 24, p. 2668-2675 8 p.

Research output: Contribution to journalArticle

Open Access

Microarray analysis of expression of cell death-associated genes in spinal cord cells with cyclic tensile strain

Uchida, K., Nakajima, H., Hirai, T., Roberts, S., Johnson, W. E. B. & Baba, H., 31 Jan 2014, Neuroprotection and regeneration of the spinal cord. Uchida, K., Nakamura, M., Ozawa, H. & et al (eds.). Tokyo (JP): Springer, p. 119-127 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Modes of action of antibacterial agents

Allison, D. G. & Lambert, P. A., 15 Oct 2014, Molecular medical microbiology. Tang, Y-W., Sussman, M., Liu, D. & et al (eds.). 2nd ed. Elsevier, Vol. 1. p. 583-598 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

New biomarkers and risk stratification in atrial fibrillation: simplicity and practicality matter

Griffiths, H. R. & Lip, G. Y. H., 18 Nov 2014, In : Circulation. 130, 21, p. 1837-1839 3 p.

Research output: Contribution to journalEditorial

Nicotine exposure reduces cell viability but induces anti-inflammatory effects in human cystic fibrosis bronchial epithelial cells

Pallett, R., Leslie, L. J. & Marshall, L. J., 27 Nov 2014.

Research output: Contribution to conferencePoster

Novel expression of microRNAs in serum samples of Iraqi breast cancer women

Saad, Z., Arif, M., Yassen, N., Jasim, H., Jelawe, M. & Brown, J., 1 May 2014, In : American Journal of Biomedicine. 2, 5, p. 567-574 8 p.

Research output: Contribution to journalArticle

Open Access
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Oxidative stress in diabetes - circulating advanced glycation end products, lipid oxidation and vascular disease

Dias, I. H. K. & Griffiths, H. R., Mar 2014, In : Annals of Clinical Biochemistry. 51, 2, p. 125-127 3 p.

Research output: Contribution to journalArticle

Open Access
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Oxidised LDL lipids, statins and a blood-brain barrier

Griffiths, H., Dias, I., Lip, G. Y. H., Spickett, C. & Polidori, C., Oct 2014, In : Free Radical Biology and Medicine. 75, Suppl.1, p. S15-S16 2 p., OP2-3.

Research output: Contribution to journalConference abstract

Oxidised LDL-lipids increase beta amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation

Dias, I. H. K., Mistry, J., Fell, S., Reis, A., Spickett, C. M., Polidori, M. C., Lip, G. Y. H. & Griffiths, H. R., Oct 2014, In : Free Radical Biology and Medicine. 75, p. 48–59 12 p.

Research output: Contribution to journalArticle

Open Access
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Paternal low protein diet affects adult offspring cardiovascular and metabolic function in mice

Watkins, A. J. & Sinclair, K. D., 15 May 2014, In : AJP Heart and Circulatory physiology. 306, 10, p. H1444-H1452 9 p.

Research output: Contribution to journalArticle

Open Access
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Performance of a two wheeled robot with extendable intermediate body on irregular terrains

Agouri, S. A., Tokhi, M. O., Almeshal, A. M., Sayidmarie, O. K. & Goher, K. M., 31 Dec 2014, Mobile Service Robotics: Proceedings of the 17th International Conference on Climbing and Walking Robots and the Support Technologies for Mobile Machines. World Scientific, p. 133-140 8 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Pharmacokinetics of a CCR5 inhibitor in rhesus macaques following vaginal, rectal and oral application

Malcolm, R. K., Lowry, D., Boyd, P., Geer, L., Veazey, R. S., Goldman, L., Klasse, P. J., Shattock, R. J. & Moore, J. P., 2014, In : Journal of Antimicrobial Chemotherapy. 69, 5, p. 1325-1329 5 p., dkt506.

Research output: Contribution to journalArticle

Physical and functional characterisation of apoptotic cell-derived extracellular vesicles

Hawkins, L., Alghareeb, K., Nadella, V., Chauhan, P., Bland, C. E. & Devitt, A., 2014.

Research output: Contribution to conferencePoster

Open Access
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Plasma irisin levels predict telomere length in healthy adults

Rana, K. S., Arif, M., Hill, E. J., Aldred, S., Nagel, D. A., Nevill, A., Randeva, H. S., Bailey, C. J., Bellary, S. & Brown, J. E., Apr 2014, In : Age. 36, 2, p. 995-1001 7 p.

Research output: Contribution to journalArticle

Open Access
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Plasma levels of HDL and carotenoids are lower in dementia patients with vascular comorbidities

Dias, I. H. K., Polidori, M. C., Li, L., Weber, D., Stahl, W., Nelles, G., Grune, T. & Griffiths, H. R., 31 Mar 2014, In : Journal of Alzheimer's disease. 40, 2, p. 399-408 10 p.

Research output: Contribution to journalArticle

Open Access
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Plasma membrane calcium ATPase isoform 4 inhibits vascular endothelial growth factor-mediated angiogenesis through interaction with calcineurin

Baggott, R. R., Alfranca, A., López-Maderuelo, D., Mohamed, T. M. A., Escolano, A., Oller, J., Ornes, B. C., Kurusamy, S., Rowther, F. B., Brown, J. E., Oceandy, D., Cartwright, E. J., Wang, W., Gómez-del Arco, P., Martínez-Martínez, S., Neyses, L., Redondo, J. M. & Armesilla, A. L., 31 Oct 2014, In : Arteriosclerosis, Thrombosis, and Vascular biology. 34, 10, p. 2310-2320 11 p.

Research output: Contribution to journalArticle

Polymeric microspheres as protein transduction reagents

Nagel, D., Behrendt, J. M., Chimonides, G. F., Torr, E. E., Devitt, A., Sutherland, A. J. & Hine, A. V., 1 Jun 2014, In : Molecular and Cellular Proteomics . 13, 6, p. 1543-1551 9 p.

Research output: Contribution to journalArticle

Open Access
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Pronounced reduction of postprandial glucagon by lixisenatide: a meta-analysis of randomized clinical trials

Ahrén, B., Gautier, J-F., Berria, R., Stager, W., Aronson, R. & Bailey, C. J., 30 Sep 2014, In : Diabetes, Obesity and Metabolism. 16, 9, p. 861-868 8 p.

Research output: Contribution to journalArticle

Redox regulation of protein damage in plasma

Griffiths, H. R., Dias, I., Willetts, R. S. & Devitt, A., 20 Jan 2014, In : Redox biology. 2, 1, p. 430-435 6 p.

Research output: Contribution to journalArticle

Open Access
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Relationship between changes in postprandial glucagon, patient characteristics, and response to lixisenatide as add-on to oral antidiabetics

Bailey, C. J., Azar, S. T., Blonde, L., Dicker, D., Puig-domingo, M., Eliaschewitz, F. G., Nikonova, E., Roussel, R., Sakaguchi, K., Sauque-Reyna, L. & Nauck, M., 30 Sep 2014, In : Diabetologia. 57, Suppl.1, p. S344 1 p., 846.

Research output: Contribution to journalConference abstract