Cell & Tissue Biomedical Research

Research Output

2011

B cell depletion in autoimmune diabetes: insights from murine models

Chamberlain, J. L., Attridge, K., Wang, C. J., Ryan, G. A. & Walker, L. S. K., 2011, In : Expert Opinion on Therapeutic Targets. 15, 6, p. 703-714 12 p.

Research output: Contribution to journalArticle

Open Access
File

Cell viability in human samples of herniated intervertebral disc: implications for biological therapies

Turner, S. A., Johnson, W. E., Trivedi, J. & Roberts, S., Sep 2011, In : Osteoarthritis and Cartilage. 19, Suppl.1, p. S214-S215 2 p., 463.

Research output: Contribution to journalConference abstract

dFOXO-independent effects of reduced insulin-like signaling in drosophila

Slack, C., Giannakou, M. E., Foley, A., Goss, M. & Partridge, L., Oct 2011, In : Aging Cell. 10, 5, p. 735-748 14 p.

Research output: Contribution to journalArticle

Open Access
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Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling

Alic, N., Andrews, T. D., Giannakou, M. E., Papatheodorou, I., Slack, C., Hoddinott, M. P., Cochemé, H. M., Schuster, E. F., Thornton, J. M. & Partridge, L., 2011, In : Molecular Systems Biology. 7, 1, 17 p., 502.

Research output: Contribution to journalArticle

Open Access
File

Immune regulation by CTLA-4-relevance to autoimmune diabetes in a transgenic mouse model

Wang, C. J., Schmidt, E. M., Attridge, K., Kenefeck, R., Wardzinski, L., Chamberlain, J. L., Soulier, A., Clough, L. E., Manzotti, C. N., Narendran, P. & Walker, L. S. K., Nov 2011, In : Diabetes/Metabolism Research and Reviews. 27, 8, p. 946-950 5 p.

Research output: Contribution to journalSpecial issue

Insulin signalling regulates remating in female drosophila

Wigby, S., Slack, C., Grönke, S., Martinez, P., Calboli, F. C. F., Chapman, T. & Partridge, L., 7 Feb 2011, In : Proceeding of the Royal Society: Series B. 278, 1704, p. 424-431 8 p.

Research output: Contribution to journalArticle

Open Access
File

In vitro chronic neurotoxicity assays: present and future developments

Nagel, D. A., Hill, E. J. & Coleman, M. D., 2011, Medical biotechnology and healthcare. Moo-Young, M. (ed.). 2nd ed. Academic Press, Vol. 5. p. 573-585 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Progesterone release from a silicone intravaginal ring in pigtailed macaques

Butler, S. E., Srinivasan, P., Lowry, D., Fetherston, S., Smith, J., Malcolm, K. & Moscoso, J., Aug 2011, In : Journal of Medical Primatology. 40, 4, p. 267 1 p., 64.

Research output: Contribution to journalConference abstract

Sustained efficacy of dapagliflozin when added to metformin in type 2 diabetes inadequately controlled by metformin monotherapy

Bailey, C. J., Gross, J. L., Yadav, M., Iqbal, N., Mansfield, T. A. & List, J. F., Sep 2011, In : Diabetologia. 54, S1, p. S67 1 p., 146.

Research output: Contribution to journalConference abstract

2010

B1 cells promote pancreas infiltration by autoreactive T cells

Ryan, G. A., Wang, C. J., Chamberlain, J. L., Attridge, K., Schmidt, E. M., Kenefeck, R., Clough, L. E., Dunussi-Joannopoulos, K., Toellner, K-M. & Walker, L. S. K., 1 Sep 2010, In : Journal of Immunology. 185, 5, p. 2800-2807 8 p.

Research output: Contribution to journalArticle

Open Access

DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition

Broughton, S. J., Slack, C., Alic, N., Metaxakis, A., Bass, T. M., Driege, Y. & Partridge, L., Jun 2010, In : Aging Cell. 9, 3, p. 336-346 11 p.

Research output: Contribution to journalArticle

Open Access

Mechanisms of life span extension by rapamycin in the fruit fly drosophila melanogaster

Bjedov, I., Toivonen, J. M., Kerr, F., Slack, C., Jacobson, J., Foley, A. & Partridge, L., 6 Jan 2010, In : Cell metabolism. 11, 1, p. 35-46 12 p.

Research output: Contribution to journalArticle

Open Access
File

Oral antidiabetic agents

Bailey, C. J. & Krentz, A. J., 9 Jul 2010, Textbook of diabetes. Holt, R. I. G., Cockram, C. S., Flyvbjerg, A. & Goldstein, B. J. (eds.). 4th ed. Wiley-Blackwell, p. 452-477 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk

Slack, C., Werz, C., Wieser, D., Alic, N., Foley, A., Stocker, H., Withers, D. J., Thornton, J. M., Hafen, E. & Partridge, L., 19 Mar 2010, In : PLoS Genetics. 6, 3, 15 p., e1000881.

Research output: Contribution to journalArticle

Open Access
File

Therapeutic Methods

Devitt, A., 6 Oct 2010, IPC No. C07K16/28, Patent No. GB 1016864.9

Research output: Patent

Open Access
2009

Preoperative skin preparation: a historical perspective

Crosby, C. T., Elliott, T. S. J., Lambert, P. A. & Adams, D., 1 Oct 2009, In : British Journal of Hospital Medicine. 70, 10, p. 579-582 4 p.

Research output: Contribution to journalArticle

Surgical site infection: are we using the right skin preparation?

Elliott, T. S. J. & Lambert, P. A., Oct 2009, In : Hospital Medicine. 70, 10, p. 552-553 2 p.

Research output: Contribution to journalArticle

2008

1,2,3-Oxadiazoles

Fraser, W., 1 Dec 2008, Comprehensive Heterocyclic Chemistry III. Elsevier, Vol. 5. p. 211-241 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

In-vitro characterization of an enzymatically cross-linked collagen-elastin like polymer scaffold

Garcia, Y., Naik, H., Collighan, R., Griffin, M., Rodriguez Cabello, J. C. & Pandit, A., 1 Dec 2008, 8th World Biomaterials Congress 2008. Vol. 2.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Oxatriazoles

Fraser, W., 1 Dec 2008, Comprehensive Heterocyclic Chemistry III. Elsevier, Vol. 6. p. 425-439 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs

Broughton, S., Alic, N., Slack, C., Bass, T., Ikeya, T., Vinti, G., Tommasi, A. M., Driege, Y., Hafen, E. & Partridge, L., 13 Nov 2008, In : PLoS ONE. 3, 11, e3721.

Research output: Contribution to journalArticle

Open Access
File
2007

Asymmetric localisation of Miranda and its cargo proteins during neuroblast division requires the anaphase-promoting complex/cyclosome

Slack, C., Overton, P. M., Tuxworth, R. I. & Chia, W., Nov 2007, In : Development. 134, 21, p. 3781-3787 7 p.

Research output: Contribution to journalArticle

Open Access
File

Can Peptidomics Provide a Useful Approach for the Identification of Biomarkers of Toxicological Exposure or Effect?

Griffiths, H., 14 May 2007, Peptidomics: Methods and Applications. Wiley, p. 341-353 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Exubera expires

Bailey, C. J., Barnett, A. H. & Day, C., 1 Nov 2007, In : British Journal of Diabetes and Vascular Disease. 7, 6, p. 255-256 2 p.

Research output: Contribution to journalArticle

Glycaemic control IS important

Day, C. & Bailey, C. J., 1 Sep 2007, In : British Journal of Diabetes and Vascular Disease. 7, 5, p. 197-198 2 p.

Research output: Contribution to journalArticle

Treating insulin resistance: Future prospects

Bailey, C. J., 1 Mar 2007, In : Diabetes and Vascular Disease Research. 4, 1, p. 20-31 12 p.

Research output: Contribution to journalArticle

2006

A consensus algorithm for treating hyperglycaemia in type 2 diabetes

Bailey, C. J., Day, C. & Campbell, I. W., 1 Jul 2006, In : British Journal of Diabetes and Vascular Disease. 6, 4, p. 147-148 2 p.

Research output: Contribution to journalEditorial

A mosaic genetic screen for novel mutations affecting Drosophila neuroblast divisions

Slack, C., Somers, W. G., Sousa-Nunes, R., Chia, W. & Overton, P. M., 2006, In : Genetics. 7, 33.

Research output: Contribution to journalArticle

Open Access
File

Increasing choice to treat obesity

Bailey, C. J. & Day, C., 1 May 2006, In : British Journal of Diabetes and Vascular Disease. 6, 3

Research output: Contribution to journalEditorial

Inhaled insulin: new technology, new possibilities

Bellary, S. & Barnett, A. H., Jun 2006, In : International Journal of Clinical Practice. 60, 6, p. 728-34 7 p.

Research output: Contribution to journalReview article

Inhaled insulin (Exubera): Combining efficacy and convenience

Bellary, S. & Barnett, A. H., Dec 2006, In : Diabetes and Vascular Disease Research. 3, 3, p. 179-85 7 p.

Research output: Contribution to journalReview article

Response to Drs Widmer and Bollinger

Adams, D., Karpanen, T., Worthington, T., Lambert, P. & Elliott, T. S. J., 1 Aug 2006, In : Journal of Hospital Infection. 63, 4, p. 479-480 2 p.

Research output: Contribution to journalLetter

2005

Degradation, insulin secretion, and antihyperglycemic actions of two palmitate-derivitized N-terminal pyroglutamyl analogues of glucose-dependent insulinotropic polypeptide

Irwin, N., Green, B. D., Gault, V. A., Greer, B., Harriott, P., Bailey, C. J., Flatt, P. R. & O'Harte, F. P. M., 2005, In : Journal of Medicinal Chemistry. 48, 4, p. 1244-1250 7 p.

Research output: Contribution to journalArticle

Early detection of coronary heart disease in diabetic patients without symptoms of coronary artery disease: Implications for expanded use of myocardial perfusion imaging

Bax, J. J., Bonow, R. O., Tschöepe, D., Inzucchi, S. E., Barrett, E. J., Bailey, C. J., Buchpiguel, C. A., Chua, T., Cuocolo, A., Freeman, M. R., Lahiri, A., Arrieta, M. O., Poirier, P. & Slama, G., 1 Sep 2005, In : British Journal of Diabetes and Vascular Disease. 5, 5, p. 283-288 6 p.

Research output: Contribution to journalArticle

Improving glucose management: Ten steps to get more patients with type 2 diabetes to glycaemic goal

Del Prato, S., Felton, A. M., Munro, N., Nesto, R., Zimmet, P., Zinman, B., Alberti, G., Aschner, P., Bailey, C. J., Blonde, L., Goldstein, B., Gomis, R., Horton, E., LaSalle, J., Lee, H. K., Leiter, L., Matthaei, S. & McGill, M., 1 Nov 2005, In : International Journal of Clinical Practice. 59, 11, p. 1345-1355 11 p.

Research output: Contribution to journalArticle

Overview of new and developing pharmacological treatments

Bailey, C. J., 1 Jun 2005, In : European Heart Journal Supplements. 7, Suppl D, p. D23–D26

Research output: Contribution to journalArticle

Synthesis and antibacterial activities of 5-hydroxy-4-amino-2(5H)-furanones

Lattmann, E., Dunn, S., Niamsanit, S. & Sattayasai, N., 15 Feb 2005, In : Bioorganic and Medicinal Chemistry Letters. 15, 4, p. 919-921 3 p.

Research output: Contribution to journalArticle

2004

Alkylboron and -silicon Compounds

Fraser, W., 1 Dec 2004, Comprehensive Organic Functional Group Transformations II. Elsevier, Vol. 2. p. 485-530 46 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Metformin: its botanical background

Bailey, C. J. & Day, C., 1 Apr 2004, In : Practical Diabetes International. 21, 3, p. 115-117 3 p.

Research output: Contribution to journalArticle

N-alkylation of N-monosubstituted sulfonamides in ionic liquids

Hu, Y., Chen, Z. C., Le, Z. G. & Zheng, Q. G., 1 Aug 2004, In : Organic Preparations and Procedures International. 36, 4, p. 347-351 5 p.

Research output: Contribution to journalArticle

Organic reactions in ionic liquids: An efficient method for the synthesis of aryl sulfones by alkylation of sodium arenesulfinates with alkyl halides

Hu, Y., Chen, Z. C., Le, Z. G. & Zheng, Q. G., 1 Apr 2004, In : Journal of Chemical Research. 4, p. 267-269 3 p.

Research output: Contribution to journalArticle

Organic Reactions in Ionic Liquids: Ionic Liquid-Accelerated Nucleophilic Substitution Reaction of α-Tosyloxyketones with Potassium Salts of Aromatic Acids

Liu, Z., Chen, Z. C. & Zheng, Q. G., 5 Jan 2004, In : Synthesis. 1, p. 33-36 4 p.

Research output: Contribution to journalArticle

2003

Deoxycytidine glyoxal: Lesion induction and evidence of repair following vitamin C supplementation in vivo

Cooke, M. S., Mistry, N., Ahmad, J., Waller, H., Langford, L., Bevan, R. J., Evans, M. D., Jones, G. D. D., Herbert, K. E., Griffiths, H. R. & Lunec, J., 15 Jan 2003, In : Free Radical Biology and Medicine. 34, 2, p. 218-225 8 p.

Research output: Contribution to journalArticle

2002

Biomarkers

Griffiths, H. R., Møller, L., Bartosz, G., Bast, A., Bertoni-Freddari, C., Collins, A., Cooke, M., Coolen, S., Haenen, G., Hoberg, A. M., Loft, S., Lunec, J., Olinski, R., Parry, J., Pompella, A., Poulsen, H., Verhagen, H. & Astley, S. B., Feb 2002, In : Molecular Aspects of Medicine. 23, 1-3, p. 101-208 108 p.

Research output: Contribution to journalArticle

Cellular impermeability and uptake of biocides and antibiotics in Gram-positive bacteria and mycobacteria

Lambert, P. A., May 2002, In : Society for Applied Microbiology. Symposium series. 92, S1, p. 46 S-54 S 10 p.

Research output: Contribution to journalArticle

Leptin prevents the fall in plasma osteocalcin during starvation in male mice

Goldstone, A. P., Howard, J. K., Lord, G. M., Ghatei, M. A., Gardiner, J. V., Wang, Z. L., Wang, R. M., Girgis, S. I., Bailey, C. J. & Bloom, S. R., 12 Jul 2002, In : Biochemical and Biophysical Research Communications. 295, 2, p. 475-481 7 p.

Research output: Contribution to journalArticle

The flavonoid galangin inhibits the L1 metallo-β-lactamase from Stenotrophomonas maltophilia

Denny, B. J., Lambert, P. A. & West, P. W. J., 19 Feb 2002, In : FEMS Microbiology Letters. 208, 1, p. 21-24 4 p.

Research output: Contribution to journalArticle