Cell & Tissue Biomedical Research

Research Output

Filter
Article
2015

Novel ageing-biomarker discovery using data-intensive technologies

Griffiths, H. R., Augustyniak, E. M., Bennett, S. J., Debacq-Chainiaux, F., Dunston, C. R., Kristensen, P., Melchjorsen, C. J., Navarrete, S. A., Simm, A. & Toussaint, O., 2015, In : Mechanisms of Ageing and Development. 151, p. 114-121 8 p.

Research output: Contribution to journalArticle

Open Access
File

Pericytes contribute to airway remodeling in a mouse model of chronic allergic asthma

Johnson, J. R., Folestad, E., Rowley, J. E., Noll, E. M., Walker, S. A., Lloyd, C. M., Rankin, S. M., Pietras, K., Eriksson, U. & Fuxe, J., 1 Apr 2015, In : AJP: Lung Cellular and Molecular Physiology. 308, 7, p. L658-L671 14 p.

Research output: Contribution to journalArticle

Open Access
File

Pharmacotherapies to manage diabesity: an update

Day, C. & Bailey, C. J., 2015, In : Diabesity in practice. 4, 1, p. 14-23 10 p.

Research output: Contribution to journalArticle

Poly(N-isopropylacrylamide-co-allylamine) (PNIPAM-co-ALA) nanospheres for the thermally triggered release of Bacteriophage K

Hathaway, H., Alves, D. R., Bean, J., Perez Esteban, P., Ouadi, K., Mark Sutton, J. & Jenkins, A. T. A., 1 Oct 2015, In : European Journal of Pharmaceutics and Biopharmaceutics. 96, p. 437-441 5 p.

Research output: Contribution to journalArticle

Redox control of protein degradation

Pajares, M., Jiménez-Moreno, N., Dias, I. H. K., Debelec, B., Vucetic, M., Fladmark, K. E., Basaga, H., Ribaric, S., Milisav, I. & Cuadrado, A., Dec 2015, In : Redox biology. 6, p. 409-420 12 p.

Research output: Contribution to journalArticle

Open Access
File

Safety of antidiabetes medications: an update

Bailey, C. J., 31 Aug 2015, In : Clinical pharmacology and therapeutics. 98, 2, p. 185–195 11 p.

Research output: Contribution to journalArticle

Serum α-tocopherol has a nonlinear inverse association with periodontitis among US adults

Zong, G., Scott, A. E., Griffiths, H. R., Zock, P. L., Dietrich, T. & Newson, R. S., 1 May 2015, In : Journal of Nutrition. 145, 5, p. 893-899 7 p.

Research output: Contribution to journalArticle

Statnote 40: Cochran's Q test

Armstrong, R. & Hilton, A., 1 Mar 2015, Microbiologist, 16, 1, p. 31-33 3 p.

Research output: Contribution to specialist publicationArticle

The current drug treatment landscape for diabetes and perspectives for the future

Bailey, C. J., 31 Aug 2015, In : Clinical pharmacology and therapeutics. 98, 2, p. 170–184 15 p.

Research output: Contribution to journalArticle

Open Access
File

The interconnectedness of ageing: does the convoy principal apply?

Saffrey, J. & Brown, J. E., Apr 2015, In : Biogerontology. 16, 2, p. 131-132 2 p.

Research output: Contribution to journalArticle

Open Access
File

The Ras-Erk-ETS-signaling pathway is a drug target for longevity

Slack, C., Alic, N., Foley, A., Cabecinha, M., Hoddinott, M. P. & Partridge, L., 2 Jul 2015, In : Cell. 162, 1, p. 72-83 12 p.

Research output: Contribution to journalArticle

Open Access
File

Thiol redox homeostasis in neurodegenerative disease

McBean, G. J., Aslan, M., Griffiths, H. R. & Torrão, R. C., Aug 2015, In : Redox biology. 5, p. 186-194 9 p.

Research output: Contribution to journalArticle

Open Access
File

Transglutaminase 2 interacts with syndecan-4 and CD44 at the surface of human macrophages to promote removal of apoptotic cells

Nadella, V., Wang, Z., Johnson, T. S., Griffin, M. & Devitt, A., Jan 2015, In : BBA - Molecular Cell Research. 1853, 1, p. 201-212 12 p.

Research output: Contribution to journalArticle

File

Validation of protein carbonyl measurement: a multi-centre study

Augustyniak, E., Adam, A., Wojdyla, K., Rogowska-Wrzesinska, A., Willetts, R., Korkmaz, A., Atalay, M., Weber, D., Grune, T., Borsa, C., Gradinaru, D., Chand Bollineni, R., Fedorova, M. & Griffiths, H., May 2015, In : Redox biology. 4, p. 149–157 9 p.

Research output: Contribution to journalArticle

Open Access
File
2014

36 monocyte subpopulations counts and associations with global longitudinal strain in st-elevation myocardial infarction patients with normal ejection fraction

Ghattas, A., Shantsila, E., Griffiths, H. & Lip, G., 30 Jun 2014, In : Heart. 100, Suppl.3, p. A19-A20 2 p.

Research output: Contribution to journalArticle

Altered hMSC functional characteristics in short-term culture and when placed in low oxygen environments: implications for cell retention at physiologic sites

Bain, O., Detela, G., Kim, H-W., Mason, C., Mathur, A. & Wall, I. B., 31 Mar 2014, In : Regenerative medicine. 9, 2, p. 153-165 13 p.

Research output: Contribution to journalArticle

An almond-enriched diet increases plasma α-tocopherol and improves vascular function but does not affect oxidative stress markers or lipid levels

Choudhury, K., Clark, J. & Griffiths, H. R., May 2014, In : Free Radical Research. 48, 5, p. 599-606 8 p.

Research output: Contribution to journalArticle

Open Access
File

Analysis of protein carbonylation - pitfalls and promise in commonly used methods

Rogowska-Wrzesinska, A., Wojdyla, K., Nedić, O., Baron, C. P. & Griffiths, H. R., 2014, In : Free Radical Research. 48, 10, p. 1145-1162 18 p.

Research output: Contribution to journalArticle

File

Can restricting calories help you to live longer?

Brown, J. E., 13 Mar 2014, In : Post Reproductive Health. 20, 1, p. 16-18 3 p.

Research output: Contribution to journalArticle

Open Access
File

Cell-nonautonomous effects of dFOXO/DAF-16 in aging

Alic, N., Tullet, J. M., Niccoli, T., Broughton, S., Hoddinott, M. P., Slack, C., Gems, D. & Partridge, L., 27 Feb 2014, In : Cell Reports. 6, 4, p. 608-616 9 p.

Research output: Contribution to journalArticle

Open Access
File

Cellular uptake of ribonuclease A-functionalised core-shell silica microspheres

Chimonides, G. F., Behrendt, J. M., Chundoo, E., Bland, C., Hine, A. V., Devitt, A., Nagel, D. A. & Sutherland, A. J., 14 Nov 2014, In : Journal of Materials Chemistry B. 2, 42, p. 7307-7315 9 p.

Research output: Contribution to journalArticle

Open Access
File

Combined use of bacteriophage K and a novel bacteriophage to reduce Staphylococcus aureus biofilm formation

Alves, D. R., Gaudion, A., Bean, J. E., Perez Esteban, P., Arnot, T. C., Harper, D. R., Kot, W., Hansen, L. H., Enright, M. C. & Jenkins, A. T. A., Nov 2014, In : Applied and Environmental Microbiology. 80, 21, p. 6694-703 10 p.

Research output: Contribution to journalArticle

Open Access
File

Cross-linking of collagen I by tissue transglutaminase provides a promising biomaterial for promoting bone healing

Fortunati, D., Chau, D. Y. S., Wang, Z., Collighan, R. J. & Griffin, M., 31 Jul 2014, In : Amino Acids. 46, 7, p. 1751-1761 11 p.

Research output: Contribution to journalArticle

Does metabolic reprogramming underpin age-associated changes in T cell phenotype and function?

Torrão, R. C., Bennett, S. J., Brown, J. E. & Griffiths, H. R., Jun 2014, In : Free Radical Biology and Medicine. 71, p. 26–35 10 p.

Research output: Contribution to journalArticle

Open Access
File

Effect of incorporating cholesterol into DDA:TDB liposomal adjuvants on Bilayer properties, biodistribution, and immune responses

Kaur, R., Henriksen-Lacey, M., Wilkhu, J., Devitt, A., Christensen, D. & Perrie, Y., 6 Jan 2014, In : Molecular Pharmaceutics. 11, 1, p. 197-207 11 p.

Research output: Contribution to journalArticle

Open Access

Effect of maternal protein restriction during pregnancy and postweaning high-fat feeding on diet-induced thermogenesis in adult mouse offspring

Sellayah, D., Dib, L., Anthony, F. W., Watkins, A. J., Fleming, T. P., Hanson, M. A. & Cagampang, F. R., 31 Oct 2014, In : European Journal of Clinical Nutrition. 53, 7, p. 1523-1531 9 p.

Research output: Contribution to journalArticle

Elevated serum free light chains predict cardiovascular events in type 2 diabetes

Bellary, S., Faint, J. M., Assi, L. K., Hutchison, C. A., Harding, S. J., Raymond, N. T. & Barnett, A. H., 31 Jul 2014, In : Diabetes Care. 37, 7, p. 2028-2030 3 p.

Research output: Contribution to journalArticle

Enhancement of the antimicrobial properties of bacteriophage-K via stabilization using oil-in-water nano-emulsions

Perez Esteban, P., Alves, D. R., Enright, M. C., Bean, J. E., Gaudion, A., Jenkins, A. T. A., Young, A. E. R. & Arnot, T. C., 2014, In : Biotechnology Progress. 30, 4, p. 932-944 13 p.

Research output: Contribution to journalArticle

Open Access
File

Ethnic differences in health related quality of life for patients with type 2 diabetes

Jhita, T., Petrou, S., Gumber, A., Szczepura, A., Raymond, N. T. & Bellary, S., 5 Jun 2014, In : Health and Quality of Life Outcomes. 12, 10 p., 83.

Research output: Contribution to journalArticle

Open Access
File

Gene therapy strategies for the treatment of spinal cord injury

Uchida, K., Nakajima, H., Guerrero, A. R., Johnson, W. E., El Masri, W. & Baba, H., 2014, In : Therapeutic Delivery. 5, 5, p. 591-607 17 p.

Research output: Contribution to journalArticle

Heparanase and COX-2 expression as predictors of lymph node metastasis in large, high-grade breast tumors

Gawthorpe, S., Brown, J. E., Arif, M., Nightingale, P., Nevill, A. & Carmichael, A. R., 30 Jun 2014, In : Anticancer Research. 34, 6, p. 2797-2800 4 p.

Research output: Contribution to journalArticle

Open Access
File

High-throughput manufacturing of size-tuned liposomes by a new microfluidics method using enhanced statistical tools for characterization

Kastner, E., Kaur, R., Lowry, D., Moghaddam, B., Wilkinson, A. & Perrie, Y., 30 Dec 2014, In : International Journal of Pharmaceutics. 477, 1-2, p. 361-368 8 p.

Research output: Contribution to journalArticle

Open Access
File

Human aquaporins: regulators of transcellular water flow

Day, R. E., Kitchen, P., Owen, D., Bland, C., Marshall, L., Conner, A. C., Bill, R. M. & Conner, M. T., 1 May 2014, In : BBA - General Subjects. 1840, 5, p. 1492-1506

Research output: Contribution to journalArticle

Open Access
File

Hypercholesterolaemia-induced oxidative stress at the blood-brain barrier

Dias, I. H. K., Polidori, M. C. & Griffiths, H. R., Aug 2014, In : Biochemical Society Transactions. 42, 4, p. 1001-1005 5 p.

Research output: Contribution to journalArticle

Open Access
File

IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells

Attridge, K., Kenefeck, R., Wardzinski, L., Qureshi, O. S., Wang, C. J., Manzotti, C., Okkenhaug, K. & Walker, L. S. K., 1 Mar 2014, In : Journal of Immunology. 192, 5, p. 2195-2201 7 p.

Research output: Contribution to journalArticle

Insulin therapy in people with type 2 diabetes: opportunities and challenges?

Home, P., Riddle, M., Cefalu, W. T., Bailey, C. J., Bretzel, R. G., del Prato, S., Leroith, D., Schernthaner, G., van Gaal, L. & Raz, I., Jun 2014, In : Diabetes Care. 37, 6, p. 1499-1508 10 p.

Research output: Contribution to journalArticle

Open Access
File
Open Access
File

Metformin in patients with type 2 diabetes and kidney disease: a systematic review

Inzucchi, S. E., Lipska, K. J., Mayo, H., Bailey, C. J. & McGuire, D. K., 24 Dec 2014, In : JAMA: Journal of the American Medical Association. 312, 24, p. 2668-2675 8 p.

Research output: Contribution to journalArticle

Open Access

Novel expression of microRNAs in serum samples of Iraqi breast cancer women

Saad, Z., Arif, M., Yassen, N., Jasim, H., Jelawe, M. & Brown, J., 1 May 2014, In : American Journal of Biomedicine. 2, 5, p. 567-574 8 p.

Research output: Contribution to journalArticle

Open Access
File

Oxidative stress in diabetes - circulating advanced glycation end products, lipid oxidation and vascular disease

Dias, I. H. K. & Griffiths, H. R., Mar 2014, In : Annals of Clinical Biochemistry. 51, 2, p. 125-127 3 p.

Research output: Contribution to journalArticle

Open Access
File

Oxidised LDL-lipids increase beta amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation

Dias, I. H. K., Mistry, J., Fell, S., Reis, A., Spickett, C. M., Polidori, M. C., Lip, G. Y. H. & Griffiths, H. R., Oct 2014, In : Free Radical Biology and Medicine. 75, p. 48–59 12 p.

Research output: Contribution to journalArticle

Open Access
File

Paternal low protein diet affects adult offspring cardiovascular and metabolic function in mice

Watkins, A. J. & Sinclair, K. D., 15 May 2014, In : AJP Heart and Circulatory physiology. 306, 10, p. H1444-H1452 9 p.

Research output: Contribution to journalArticle

Open Access
File

Pharmacokinetics of a CCR5 inhibitor in rhesus macaques following vaginal, rectal and oral application

Malcolm, R. K., Lowry, D., Boyd, P., Geer, L., Veazey, R. S., Goldman, L., Klasse, P. J., Shattock, R. J. & Moore, J. P., 2014, In : Journal of Antimicrobial Chemotherapy. 69, 5, p. 1325-1329 5 p., dkt506.

Research output: Contribution to journalArticle

Plasma irisin levels predict telomere length in healthy adults

Rana, K. S., Arif, M., Hill, E. J., Aldred, S., Nagel, D. A., Nevill, A., Randeva, H. S., Bailey, C. J., Bellary, S. & Brown, J. E., Apr 2014, In : Age. 36, 2, p. 995-1001 7 p.

Research output: Contribution to journalArticle

Open Access
File

Plasma levels of HDL and carotenoids are lower in dementia patients with vascular comorbidities

Dias, I. H. K., Polidori, M. C., Li, L., Weber, D., Stahl, W., Nelles, G., Grune, T. & Griffiths, H. R., 31 Mar 2014, In : Journal of Alzheimer's disease. 40, 2, p. 399-408 10 p.

Research output: Contribution to journalArticle

Open Access
File

Plasma membrane calcium ATPase isoform 4 inhibits vascular endothelial growth factor-mediated angiogenesis through interaction with calcineurin

Baggott, R. R., Alfranca, A., López-Maderuelo, D., Mohamed, T. M. A., Escolano, A., Oller, J., Ornes, B. C., Kurusamy, S., Rowther, F. B., Brown, J. E., Oceandy, D., Cartwright, E. J., Wang, W., Gómez-del Arco, P., Martínez-Martínez, S., Neyses, L., Redondo, J. M. & Armesilla, A. L., 31 Oct 2014, In : Arteriosclerosis, Thrombosis, and Vascular biology. 34, 10, p. 2310-2320 11 p.

Research output: Contribution to journalArticle

Polymeric microspheres as protein transduction reagents

Nagel, D., Behrendt, J. M., Chimonides, G. F., Torr, E. E., Devitt, A., Sutherland, A. J. & Hine, A. V., 1 Jun 2014, In : Molecular and Cellular Proteomics . 13, 6, p. 1543-1551 9 p.

Research output: Contribution to journalArticle

Open Access
File

Pronounced reduction of postprandial glucagon by lixisenatide: a meta-analysis of randomized clinical trials

Ahrén, B., Gautier, J-F., Berria, R., Stager, W., Aronson, R. & Bailey, C. J., 30 Sep 2014, In : Diabetes, Obesity and Metabolism. 16, 9, p. 861-868 8 p.

Research output: Contribution to journalArticle

Redox regulation of protein damage in plasma

Griffiths, H. R., Dias, I., Willetts, R. S. & Devitt, A., 20 Jan 2014, In : Redox biology. 2, 1, p. 430-435 6 p.

Research output: Contribution to journalArticle

Open Access
File