Translational Medicine Research Group (TMRG)

2000

Release and complex formation of soluble VEGFR-1 from endothelial cells and biological fluids

Hornig, C., Barleon, B., Ahmad, S., Vuorela, P., Ahmed, A. & Weich, H. A., 1 Apr 2000, In: Laboratory Investigation. 80, 4, p. 443-454 12 p.

Research output: Contribution to journal › Article › peer-review

2001

Conditional ablation of neurones in transgenic mice

Isles, A. R., Ma, D., Milsom, C., Skynner, M. J., Cui, W., Clark, J., Keverne, E. B. & Allen, N. D., 5 Jun 2001, In: Journal of neurobiology. 47, 3, p. 183-193 11 p.

Research output: Contribution to journal › Article › peer-review

2002

A possible role for imprinted genes in inbreeding avoidance and dispersal from the natal area in mice

Isles, A. R., Baum, M. J., Ma, D., Szeto, A., Keverne, E. B. & Allen, N. D., 7 Apr 2002, In: Proceedings of the Royal Society B: Biological Sciences. 269, 1492, p. 665-670 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Protein synthetic machinery in the dendrites of the magnocellular neurosecretory neurons of wild-type Long-Evans and homozygous Brattleboro rats

Ma, D. & Morris, J. F., 1 Mar 2002, In: Journal of chemical neuroanatomy. 23, 3, p. 171-186 16 p.

Research output: Contribution to journal › Article › peer-review

Selective ablation of olfactory receptor neurons without functional impairment of vomeronasal receptor neurons in OMP-ntr transgenic mice

Ma, D., Allen, N. D., Van Bergen, Y. C. H., Jones, C. M. E., Baum, M. J., Keverne, E. B. & Brennan, P. A., 18 Dec 2002, In: European Journal of Neuroscience. 16, 12, p. 2317-2323 7 p.

Research output: Contribution to journal › Article › peer-review

2004

Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM

Ma, D., Shield, J. P. H., Dean, W., Leclerc, I., Knauf, C., Burcelin R, R. É., Rutter, G. A. & Kelsey, G., 1 Aug 2004, In: Journal of Clinical Investigation. 114, 3, p. 339-48 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2007

Effect of posterolateral left ventricular scar on mortality and morbidity following cardiac resynchronization therapy.

Chalil, S., Stegemann, B., Muhyaldeen, S., Khadjooi, K., Foley, P., Smith, R. & Leyva, F., Oct 2007, In: Pacing and Clinical Electrophysiology. 30, 10, p. 1201-1209

Research output: Contribution to journal › Article › peer-review

Intraventricular dyssynchrony predicts mortality and morbidity after cardiac resynchronization therapy: a study using cardiovascular magnetic resonance tissue synchronization imaging.

Chalil, S., Stegemann, B., Muhyaldeen, S., Khadjooi, K., Smith, R., Jordan, P. & Leyva, F., Jul 2007, In: Journal of the American College of Cardiology. 50, 3, p. 243-252

Research output: Contribution to journal › Article › peer-review

2009

Cardiac resynchronization therapy in patients with mildly impaired left ventricular function.

Foley, P., Stegemann, B., Smith, R., Sanderson, J. & Leyva, F., Mar 2009, In: Pacing and Clinical Electrophysiology. 32, s1, p. S186-S189

Research output: Contribution to journal › Article › peer-review

Development and validation of a clinical index to predict survival after cardiac resynchronisation therapy.

Leyva, F., Foley, P., Stegemann, B., Ward, J., Ng, L., Frenneaux, M., Regoli, F., Smith, R. & Auricchio, A., Oct 2009, In: Heart. 95, p. 1619-1625

Research output: Contribution to journal › Article › peer-review

Growth differentiation factor-15 predicts mortality and morbidity after cardiac resynchronization therapy.

Foley, P., Stegemann, B., Ng, K., Ramachandran, S., Proudler, A., Frenneaux, M., Ng, L. & Leyva, F., Nov 2009, In: European Heart Journal. 30, 22, p. 2749–2757

Research output: Contribution to journal › Article › peer-review

Open Access

File

Radial dyssynchrony assessed by cardiovascular magnetic resonance in relation to left ventricular function, myocardial scarring and QRS duration in patients with heart failure.

Foley, P., Khadjooi, K., Ward, J., Smith, R., Stegemann, B., Frenneaux, M. & Leyva, F., 24 Nov 2009, In: Journal of Cardiovascular Magnetic Resonance. 11, 1, 50.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Short-term hemodynamic effects of cardiac resynchronization therapy in patients with heart failure, a narrow QRS duration, and no dyssynchrony.

Williams, L., Ellery, S., Patel, K., Leyva, F., Bleasdale, R., Phan, T., Stegemann, B., Paul, V., Steendijk, P. & Frenneaux, M., 12 Oct 2009, In: Circulation. 120, 17, p. 1687–1694

Research output: Contribution to journal › Article › peer-review

2010

Deficiencia de vitamina D: ¿Factor de riesgo de síndrome metabólico? Vitamina D y síndrome metabólico

Translated title of the contribution: Association between vitamin D deficiency and metabolic syndromeSanchez Aranguren , L., 2010, In: Revista Medica de Chile. 138, 10, p. 1312-1318 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2011

Cardiac resynchronisation therapy in patients with heart failure and a normal QRS duration: the RESPOND study.

Foley, P., Patel, K., Irwin, N., Sanderson, J., Frenneaux, M., Smith, R., Stegemann, B. & Leyva, F., Jul 2011, In: Heart. 97, 13, p. 1041-1047

Research output: Contribution to journal › Article › peer-review

2012

Left ventricular midwall fibrosis as a predictor of mortality and morbidity after cardiac resynchronization therapy in patients with nonischemic cardiomyopathy.

Leyva, F., Taylor, R., Foley, P., Umar, F., Mulligan, L., Patel, K., Stegemann, B., Haddad, T., Smith, R. & Prasad, S., 23 Oct 2012, In: Journal of the American College of Cardiology. 60, 17, p. 1659-1667

Research output: Contribution to journal › Article › peer-review

Medida del colesterol de lipoproteínas de baja densidad utilizando tres metodologías: Medición de colesterol de lipoproteínas de baja densidad

Translated title of the contribution: Measurement of cholesterol low-density lipoprotein using three methodologiesQuerales, M., Cruces, M. E., Sánchez, C., Querales, M., Rojas, S. & Sanchez Aranguren , L., 2012, In: Acta Bioquimica Clinica Latinoamericana. 46, 1, p. 31-37

Research output: Contribution to journal › Article › peer-review

Open Access

File

Molecular validation of the acute phencyclidine rat model for schizophrenia: Identification of translational changes in energy metabolism and neurotransmission

Ernst, A., Ma, D., Garcia-Perez, I., Tsang, T. M., Kluge, W., Schwarz, E., Guest, P. C., Holmes, E., Sarnyai, Z. & Bahn, S., 6 Jul 2012, In: Journal of Proteome Research. 11, 7, p. 3704-3714 11 p.

Research output: Contribution to journal › Article › peer-review

Proteomic analysis of the maternal protein restriction rat model for schizophrenia: Identification of translational changes in hormonal signaling pathways and glutamate neurotransmission

Guest, P. C., Urday, S., Ma, D., Stelzhammer, V., Harris, L. W., Amess, B., Pietsch, S., Oheim, C., Ozanne, S. E. & Bahn, S., 17 Dec 2012, In: Proteomics. 12, 23-24, p. 3580-3589 10 p.

Research output: Contribution to journal › Article › peer-review

The limit of plausibility for predictors of response: application to biventricular pacing.

Nijjer, S., Pabari, P., Stegemann, B., Palmieri, V., Leyva, F., Linde, C., Freemantle, N., Davies, J., Hughes, A. & Francis, D., Oct 2012, In: JACC: Cardiovascular Imaging. 5, 10, p. 1046-1065

Research output: Contribution to journal › Article › peer-review

Tipos morfológicos, número de parásitos por campo y carga parasitaria de Blastocystis sp proveniente de pacientes sintomáticos y asintomáticos: Tipos morfológicos de Blastocystis sp

Translated title of the contribution: Morphological types, number of parasites per field and parasite load of Blastocystis sp from symptomatic and asymptomatic patientsSanchez Aranguren , L., 2012, In: Salus. 16, 3, p. 13-16 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2013

Efecto del tratamiento con praziquantel sobre la actividad de la fosfatasa alcalina, fosfatasa acida, superoxido dismutasa en extractos crudos y productos de excreción-secreción de gusanos de Schistosoma mansoni: Praziquantel y enzimas de Schistosoma mansoni

Translated title of the contribution: Effect of Treatment with Praziquantel on the activity of alkaline phosphatase acid phosphatase, superoxide dismutase in Crude Extracts and Excretion-secretion Products of Schistosoma mansoni wormsBarrios, E. E., Rodríguez, J., Richani, N., Araque, W., Quintana, J. F. & Sanchez Aranguren , L., 2013, In: Salus. 17, Suppl 1, p. 46-55 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Fibronectin aggregation in multiple sclerosis lesions impairs remyelination

Stoffels, J. M. J., De Jonge, J. C., Stancic, M., Nomden, A., Van Strien, M. E., Ma, D., Šišková, Z., Maier, O., Ffrench-Constant, C., Franklin, R. J. M., Hoekstra, D., Zhao, C. & Baron, W., 28 Jan 2013, In: Brain. 136, 1, p. 116-131 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2014

Feature-tracking cardiovascular magnetic resonance as a novel technique for the assessment of mechanical dyssynchrony.

Taylor, R., Umar, F., Moody, W., Meyyappan, C., Stegemann, B., Townend, J., Hor, K., Miszalski-Jamka, T., Mazur, W., Steeds, R. & Leyva, F., 15 Jul 2014, In: International Journal of Cardiology. 175, 1, p. 120-125

Research output: Contribution to journal › Article › peer-review

Mechanical effects of midwall fibrosis in non-ischemic dilated cardiomyopathy.

Taylor, R., Umar, F., Lin, L., Ahmed, A., Moody, W., Stegemann, B., Townend, J., Steeds, R. & Leyva, F., 16 Jan 2014, In: Journal of Cardiovascular Magnetic Resonance. 18, 1

Research output: Contribution to journal › Conference article › peer-review

Open Access

File

2015

Drug repurposing screen identifies Foxo1-dependent angiopoietin-2 regulation in sepsis

Ghosh, C. C., Thamm, K., Berghelli, A. V., Schrimpf, C., Maski, M. R., Abid, T., Milam, K. E., Rajakumar, A., Santel, A., Kielstein, J. T., Ahmed, A., Thickett, D., Wang, K., Chase, M., Donnino, M. W., Aird, W. C., Haller, H., David, S. & Parikh, S. M., Jul 2015, In: Critical Care Medicine. 43, 7, p. e230-e240 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

High glucose and interleukin 1β-induced apoptosis in human umbilical vein endothelial cells involves in down-regulation of monocarboxylate transporter 4

Wang, D., Wang, Q., Yan, G., Qiao, Y., Sun, L., Zhu, B., Tang, C. & Gu, Y., 30 Oct 2015, In: Biochemical and Biophysical Research Communications. 466, 4, p. 607-614

Research output: Contribution to journal › Article › peer-review

Myocardial strain measurement with feature-tracking cardiovascular magnetic resonance: normal values.

Taylor, R., Moody, W., Umar, F., Edwards, N., Taylor, T., Stegemann, B., Townend, J., Hor, K., Steeds, R., Mazur, W. & Leyva, F., 1 Aug 2015, In: European Heart Journal- Cardiovascular Imaging. 16, 8, p. 871–881

Research output: Contribution to journal › Article › peer-review

NANOPARTICLES WITH ATTACHED DNA REPAIR INHIBITORS AND NUCLEAR LOCALISATION SIGNAL ELEMENTS

Kysela, B. (Inventor), 21 Aug 2015, IPC No. C07K 14/ 47 A I, Patent No. IN10124DELNP2014, Priority date 28 May 2013, Priority No. WO2013GB51401

Research output: Patent

Open Access

Sepiapterin restores the Metabolic Phenotype Switch Induced by Anti-angiogenic Factors in Preeclampsia

Sanchez Aranguren , L., Nov 2015.

Research output: Unpublished contribution to conference › Poster › peer-review

2016

5-HTR3 and 5-HTR4 located on the mitochondrial membrane and functionally regulated mitochondrial functions

Wang, Q., Zhang, H., Xu, H., Guo, D., Shi, H., Li, Y., Zhang, W. & Gu, Y., 22 Nov 2016, In: Scientific Reports. 6, 10 p., 37336.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Haemodynamic effects of cardiac resynchronization therapy using single-vein, three-pole, multipoint left ventricular pacing in patients with ischaemic cardiomyopathy and a left ventricular free wall scar: the MAESTRO study

Umar, F., Taylor, R., Stegemann, B., Marshall, H., Flannigan, S., Lencioni, M., De, B. J., Griffith, M. & Leyva, F., 1 Aug 2016, In: Europace. 18, 8, p. 1227-1234

Research output: Contribution to journal › Article › peer-review

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to the development of pulmonary arterial hypertension

Guo, D., Gu, J., Jiang, H., Ahmed, A., Zhang, Z. & Gu, Y., Feb 2016, In: Journal of Molecular and Cellular Cardiology. 91, p. 179-187 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Role of epithelial Na⁺ channels in endothelial function

Guo, D., Liang, S., Wang, S., Tang, C., Yao, B., Wan, W., Zhang, H., Jiang, H., Ahmed, A., Zhang, Z. & Gu, Y., 1 Jan 2016, In: Journal of Cell Science. 129, 2, p. 290-297 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Sepiapterin, a potential therapeutic approach to restore the metabolic phenotype switch induced by sFlt-1 in preeclampsia

Sanchez Aranguren , L., Oct 2016.

Research output: Unpublished contribution to conference › Abstract › peer-review

2017

A protocol for producing the maternal low-protein rat model: A tool for preclinical proteomic studies

Ma, D., Ozanne, S. E. & Guest, P. C., 29 Mar 2017, Advances in Experimental Medicine and Biology. Guest, P. (ed.). Springer, p. 251-255 5 p. (Advances in Experimental Medicine and Biology; vol. 974).

Research output: Chapter in Book/Published conference output › Chapter

Open Access

Generation of the acute phencyclidine rat model for proteomic studies of schizophrenia

Ma, D. & Guest, P. C., 29 Mar 2017, Advances in Experimental Medicine and Biology. Guest, P. (ed.). Springer, p. 257-261 5 p. (Advances in Experimental Medicine and Biology; vol. 974).

Research output: Chapter in Book/Published conference output › Chapter

Heterodimerisation between VEGFR-1 and VEGFR-2 and not the homodimers of VEGFR-1 inhibit VEGFR-2 activity

Cai, M., Wang, K., Murdoch, C. E., Gu, Y. & Ahmed, A., Jan 2017, In: Vascular Pharmacology. 88, p. 11-20 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

In vitro experimental results using autofluorescence spectroscopy to assess RF ablation of bovine heart

Tsatsakoulias, A., Litvinova, K. S., Leyva, F. & Rafailov, E. U., 30 Oct 2017, The European Conference on Lasers and Electro-Optics, CLEO_Europe 2017. (Optics InfoBase Conference Papers; vol. Part F82-CLEO_Europe 2017).

Research output: Chapter in Book/Published conference output › Conference publication

Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels

Rana, K. S., Pararasa, C., Afzal, I., Nagel, D. A., Hill, E. J., Bailey, C. J., Griffiths, H. R., Kyrou, I., Randeva, H. S., Bellary, S. & Brown, J. E., 9 Nov 2017, In: Cardiovascular Diabetology. 16, 1, 147.

Research output: Contribution to journal › Article › peer-review

Open Access

File

The Italian version of the Wong-Law Emotional Intelligence Scale(WLEIS-I): A second-order factor analysis

Iliceto, P. & Fino, E., 1 Oct 2017, In: Personality and Individual Differences. 116, p. 274-280

Research output: Contribution to journal › Article › peer-review

Thyroid hormone therapy for older adults with subclinical hypothyroidism

Weickert, M. O. & Kyrou, I., 5 Oct 2017, In: New England Journal of Medicine. 377, 14, p. e20.2-e20.3

Research output: Contribution to journal › Letter, comment/opinion or interview › peer-review

TREATMENT OF NEUROLOGICAL PATHOLOGIES WITH INHIBITORS OF DNA DAMAGE REPAIR

Kysela, B. (Inventor), Ahmed, Z. (Inventor) & Tuxworth, R. (Inventor), 23 Nov 2017, IPC No. A61P 25/ 00 A I, Patent No. WO2017199042, Priority date 20 May 2016, Priority No. GB20160008885

Research output: Patent

Open Access

2018

A Subpopulation of Foxj1-Expressing, Nonmyelinating Schwann Cells of the Peripheral Nervous System Contribute to Schwann Cell Remyelination in the Central Nervous System

Ma, D., Wang, B., Zawadzka, M., Gonzalez, G., Wu, Z., Yu, B., Rawlins, E. L., Franklin, R. J. M. & Zhao, C., 24 Oct 2018, In: Journal of Neuroscience. 38, 43, p. 9228-9239

Research output: Contribution to journal › Article › peer-review

Open Access

File

Atrioventricular junction ablation in patients with atrial fibrillation treated with cardiac resynchronization therapy: Positive impact on ventricular arrhythmias, implantable cardioverter-defibrillator therapies and hospitalizations

Gasparini, M., Kloppe, A., Lunati, M., Anselme, F., Landolina, M., Martinez-Ferrer, J. B., Proclemer, A., Morani, G., Biffi, M., Ricci, R., Rordorf, R., Mangoni, L., Manotta, L., Grammatico, A., Leyva, F. & Boriani, G., 10 Oct 2018, In: European Journal of Heart Failure. 20, 10, p. 1472-1481 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

BHDPC is a novel neuroprotectant that provides anti-neuroinflammatory and neuroprotective effects by inactivating NF-κB and activating PKA/CREB

Li, C., Chen, T., Zhou, H., Feng, Y., Hoi, M. P. M., Ma, D., Zhao, C., Zheng, Y. & Lee, S. M. Y., 25 Jun 2018, In: Frontiers in Pharmacology. 9, 614.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Breakfast and subclinical atherosclerosis: a novel association that highlights the importance of dietary habits in the prevention of atherosclerotic diseases

Sanchez Aranguren , L. & Ahmed, A., 10 Sept 2018, In: Annals of Research Hospitals. 2018, p. 1-3 3 p.

Research output: Contribution to journal › Editorial

Elevated mitochondrial SLC25A29 in cancer modulates metabolic status by increasing mitochondria-derived nitric oxide

Zhang, H., Wang, Q., Gu, J., Yin, L., Liang, S., Wu, L., Xu, H., Zhao, C. & Gu, Y., 20 Feb 2018, In: Oncogene. 37, p. 2545-2558

Research output: Contribution to journal › Article › peer-review

Generation of the maternal low-protein rat model for studies of metabolic disorders

Ma, D., Ozanne, S. E. & Guest, P. C., 30 Jan 2018, Methods in Molecular Biology. Guest, P. (ed.). Humana Press, p. 201-206 6 p. (Methods in Molecular Biology; vol. 1735).

Research output: Chapter in Book/Published conference output › Chapter

Open Access

Hyperlocomotion test for assessing behavioral disorders

Ma, D. & Guest, P. C., 30 Jan 2018, Methods in Molecular Biology. Guest, P. (ed.). Humana Press, p. 421-425 5 p. (Methods in Molecular Biology; vol. 1735).

Research output: Chapter in Book/Published conference output › Chapter

Translational Medicine Research Group (TMRG)

Research output

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