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Research Output

2020

Evaluation of anti-biofilm activity of acidic amino acids and synergy with ciprofloxacin on Staphylococcus aureus biofilms

Warraich, A. A., Mohammed, A. R., Perrie, Y., Hussain, M., Gibson, H. & Rahman, A., 2 Jun 2020, In : Scientific Reports. 10, 1, 9021.

Research output: Contribution to journalArticle

Open Access
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Multimodal role of amino acids in microbial control and drug development

Idrees, M., Mohammad, A. R., Karodia, N. & Rahman, A., 17 Jun 2020, In : Antibiotics. 9, 6, 23 p., 330.

Research output: Contribution to journalReview article

Open Access
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2019

Conceptualisation, Development, Fabrication and In Vivo Validation of a Novel Disintegration Tester for Orally Disintegrating Tablets

Koner, J., Rajabi-Siahboomi, A., Missaghi, S., Kirby, D. J., Perrie, Y., Ahmed, J. & Mohammed, A., 28 Aug 2019, In : Scientific Reports. 9, 12467 .

Research output: Contribution to journalArticle

Open Access
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Delivery of Poorly Soluble Drugs via Mesoporous Silica: Impact of Drug Overloading on Release and Thermal Profiles

Le, T., Elzhry Elyafi, A. K., Mohammed, A. R. & Al-khattawi, A., 10 Jun 2019, In : Pharmaceutics. 11, 6, 269.

Research output: Contribution to journalArticle

Open Access
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High-throughput screening of excipients with a biological effect: a kinetic study on the effects of surfactants on efflux-mediated transport

Pollard, J., Rajabi-siahboomi, A., Badhan, R. K. S., Mohammed, A. R. & Perrie, Y., 1 Jun 2019, In : Journal of Pharmacy and Pharmacology. 71, 6, p. 889-897 9 p.

Research output: Contribution to journalArticle

Open Access
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2018
Open Access
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Development, Optimisation, Validation and Inter-Laboratory Verification of a Reversed Phase HPLC Method for Quantification of Human Recombinant Insulin

Iyrie, A., Russell, C., Dennision, T., Rajoli, R., Saleem, I. Y., Rahman, A. S. & Mohammed, A., 30 Mar 2018, In : Journal of Advance in Biotechnology.

Research output: Contribution to journalArticle

Open Access
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Dry particle coating a unique solution for pharmaceutical formulation

Koner, J. S., Dahmash, E. Z., Wyatt, D. A. & Mohammed, A., 1 Mar 2018, In : Pharmaceutical Technology Europe. 30, 3, p. 20-23 4 p.

Research output: Contribution to journalArticle

Dry particle coating-a unique solution for pharmaceutical formulation

Koner, J. S., Dahmash, E. Z., Wyatt, D. A. & Mohammed, A., 1 Mar 2018, In : Pharmaceutical Technology. 42, 3, p. 26-30 5 p.

Research output: Contribution to journalArticle

Open Access
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Quality by Design (QbD) based process optimisation to develop functionalised particles with modified release properties using novel dry particle coating technique

Dahmash, E. Z., Al-Khattawi, A., Iyire, A., Al-Yami, H., Dennison, T. J. & Mohammed, A. R., 1 Nov 2018, In : PLoS ONE. 13, 11, e0206651.

Research output: Contribution to journalArticle

Open Access
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Understanding the compaction behaviour of low-substituted HPC: macro, micro, and nano-metric evaluations

ElShaer, A., Al-Khattawi, A., Mohammed, A. R., Warzecha, M., Lamprou, D. A. & Hassanin, H., 2018, In : Pharmaceutical Development and Technology. 23, 5, p. 442-453

Research output: Contribution to journalArticle

Open Access
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2017
Open Access
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Colonic delivery of indometacin loaded PGA-co-PDL microparticles coated with Eudragit L100-55 from fast disintegrating tablets

Tawfeek, H. M., Abdellatif, A. A. H., Dennison, T. J., Mohammed, A. R., Sadiq, Y. & Saleem, I. Y., 5 Oct 2017, In : International Journal of Pharmaceutics. in press, p. 80-89 10 p.

Research output: Contribution to journalArticle

Open Access
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Open Access
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Environmental scanning electron microscope imaging of vesicle systems

Perrie, Y., Ali, H., Kirby, D. J., Mohammed, A. U. R., McNeil, S. E. & Vangala, A., 2017, Liposomes: methods and protocols. d'Souza, G. G. M. (ed.). New York (US): Springer, p. 131-143 13 p. (Methods in Molecular Biology; vol. 1522).

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access
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Multiparticulate systems for paediatric drug delivery

Iyrie, A. & Mohammed, A. R., 2017, Multiparticulate drug delivery: formulation, processing and manufacture. Rajabi-Siahboomi, A. R. (ed.). New York< NY (US): Springer, p. 213-236 24 p. (Advances in Delivery Science Technology).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

2016

Characterisation and surface-profiling techniques for composite particles produced by dry powder coating in pharmaceutical drug delivery

Dahmash, E. Z. & Mohammed, A. R., Apr 2016, In : Drug Discovery Today. 21, 4, p. 550-561 12 p.

Research output: Contribution to journalReview article

Open Access
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Design of experiments to study the impact of process parameters on droplet size and development of non-invasive imaging techniques in tablet coating

Dennison, T. J., Smith, J., Hofmann, M. P., Bland, C. E., Badhan, R. K., Al-Khattawi, A. & Mohammed, A. R., 22 Aug 2016, In : PLoS ONE. 11, 8, 17 p., e0157267.

Research output: Contribution to journalArticle

Open Access
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Open Access
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Open Access
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2015

A holistic multi evidence approach to study the fragmentation behaviour of crystalline mannitol

Koner, J. S., Rajabi-Siahboomi, A., Bowen, J., Perrie, Y., Kirby, D. & Mohammed, A. R., 10 Nov 2015, In : Scientific Reports. 5, 12 p., 16352.

Research output: Contribution to journalArticle

Open Access
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A methodological evaluation and predictive in silico investigation into the multi-functionality of arginine in directly compressed tablets

ElShaer, A., Kaialy, W., Akhtar, N., Iyrie, A., Hussain, T., Alany, R. & Mohammed, A. R., Oct 2015, In : European Journal of Pharmaceutics and Biopharmaceutics. 96, p. 272–281 10 p.

Research output: Contribution to journalArticle

Open Access
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A pragmatic approach for engineering porous mannitol and mechanistic evaluation of particle performance

Al-Khattawi, A., Koner, J., Rue, P., Kirby, D., Perrie, Y., Rajabi-Siahboomi, A. & Mohammed, A. R., 7 May 2015, In : European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
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Functionalised particles using dry powder coating in pharmaceutical drug delivery: promises and challenges

Dahmash, E. Z. & Mohammed, A. R., 2015, In : Expert Opinion on Drug Delivery. 12, 12, p. 1867-1879 13 p.

Research output: Contribution to journalArticle

Open Access
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Paediatric drug development of ramipril: reformulation, in vitro and in vivo evaluation

Russell, C., Begum, S., Hussain, Y., Hussain, M., Huen, D., Rahman, A. S., Perrie, Y. & Mohammed, A. R., 2015, In : Journal of Drug Targeting. 23, 9, p. 854-863 10 p.

Research output: Contribution to journalArticle

Open Access
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2014

Drug bioavailability and gene profiling: challenges and opportunities for pharmaceutics and personalized medicine

Mohammed, A. R., ElShaer, A. M., Jones, R. J., Khan, S. & Russell, C. A., 12 Feb 2014, Handbook of personalized medicine: advances in nanotechnology, drug delivery and therapy. Vizirianakis, I. S. (ed.). Boca Raton, FL (US): CRC Press, p. 141-190 50 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Evidence-based nanoscopic and molecular framework for excipient functionality in compressed orally disintegrating tablets

Al-Khattawi, A., Alyami, H., Townsend, B., Ma, X. & Mohammed, A. R., 15 Jul 2014, In : PLoS ONE. 9, 7, 13 p., e101369.

Research output: Contribution to journalArticle

Open Access
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Excipients in medicines for children: scientific and regulatory paradigms

Al-Khattawi, A. & Mohammed, A. R., 15 Apr 2014, In : European Pharmaceutical Review. 19, 2, p. 67-70 4 p.

Research output: Contribution to journalArticle

Investigating buccal cell cultures to enhance in vitro assessment of transmucosal drug delivery

Iyrie, A., Russell, C., Bailey, C. J. & Mohammed, A., 2014, UKICRS Newsletter, p. 38-40 3 p.

Research output: Contribution to specialist publicationFeatured article

Open Access

Systematic screening of compressed ODT excipients: cellulosic versus non-cellulosic

Al-Khattawi, A., Iyrie, A., Dennison, T., Dahmash, E., Bailey, C. J., Smith, J., Rue, P. & Mohammed, A. R., 23 Mar 2014, In : Current Drug Delivery. 11, 4, p. 486-500 15 p.

Research output: Contribution to journalArticle

2013

Application of genomics, proteomics and metabolomics in drug discovery, development and clinic

Russell, C., Rahman, A. & Mohammed, A. R., Mar 2013, In : Therapeutic Delivery. 4, 3, p. 395-413 19 p.

Research output: Contribution to journalReview article

A Systematic Investigation of D-Mannitol Functionality in the Development of Age-Appropriate Formulations

Al-Khattawi, A. A., Alyami, H. & Mohammed, A., 2013, Controlled Release Society Newsletter, 30, 3, p. 20-21.

Research output: Contribution to specialist publicationArticle

Designing nonionic surfactant vesicles for the delivery of antigens for systemic and alternative delivery routes

Wilkhu, J., Vangala, A., Mohammed, A. R. & Perrie, Y., 2013, Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines. Springer, p. 205-232 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dissolution rate enhancement, in vitro evaluation and investigation of drug release kinetics of chloramphenicol and sulphamethoxazole solid dispersions

Khan, S., Batchelor, H., Hanson, P., Saleem, I. Y., Perrie, Y. & Mohammed, A. R., May 2013, In : Drug Development and Industrial Pharmacy. 39, 5, p. 704-715 12 p.

Research output: Contribution to journalArticle

Dry powder inhalation of macromolecules using novel PEG-co-polyester microparticle carriers

Tawfeek, H. M., Evans, A. R., Iftikhar, A., Mohammed, A. R., Shabir, A., Somavarapu, S., Hutcheon, G. A. & Saleem, I. Y., 30 Jan 2013, In : International Journal of Pharmaceutics. 441, 1-2, p. 611-619 9 p.

Research output: Contribution to journalArticle

The role of lipid geometry in designing liposomes for the solubilisation of poorly water soluble drugs

Ali, M. H., Moghaddam, B., Kirby, D. J., Mohammed, A. R. & Perrie, Y., 30 Aug 2013, In : International Journal of Pharmaceutics. 453, 1, p. 225-232 8 p.

Research output: Contribution to journalArticle

Open Access
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2012

Preparation and characterisation of amino acids based trimethoprim salts

ElShaer, A., Hanson, P., Worthington, T., Lambert, P. & Mohammed, A. R., 16 Feb 2012, In : Pharmaceutics. 4, 1, p. 179-196 17 p., 4.

Research output: Contribution to journalArticle

File

The impact of ageing on the barriers to drug delivery

Perrie, Y., Singh Badhan, R., Kirby, D. J., Lowry, D., Mohammed, A-U-R. & Ouyang, D., 20 Jul 2012, In : Journal of Controlled Release. 161, 2, p. 389-398 10 p.

Research output: Contribution to journalArticle

Trigger release liposome systems: local and remote controlled delivery?

Bibi, S., Lattmann, E., Mohammed, A-U-R. & Perrie, Y., May 2012, In : Journal of Microencapsulation. 29, 3, p. 262-276 15 p.

Research output: Contribution to journalArticle

2011

Effects of ball-milling on PLGA polymer and its implication on lansoprazole-loaded nanoparticles

Shabir, A., Alhusban, F., Perrie, Y. & Mohammed, A. R., Mar 2011, In : Journal of Basic and Clinical Pharmacy. 2, 2, p. 71-82 12 p.

Research output: Contribution to journalArticle

Open Access
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Exploring the correlation between lipid packaging in lipoplexes and their transfection efficacy

Moghaddam, B., McNeil, S. E., Zheng, Q., Mohammed, A. R. & Perrie, Y., 18 Nov 2011, In : Pharmaceutics. 3, 4, p. 848-864 17 p.

Research output: Contribution to journalArticle

Open Access
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Formulation of multiparticulate systems as lyophilised orally disintegrating tablets

Al Husban, F., Perrie, Y. & R. Mohammed, A-U-R., Nov 2011, In : European Journal of Pharmaceutics and Biopharmaceutics. 79, 3, p. 627-634 7 p.

Research output: Contribution to journalArticle

Genomic evaluation during permeability of indomethacin and its solid dispersion

Khan, S., Elshaer, A., Rahman, A. S., Hanson, P., Perrie, Y. & Mohammed, A-U-R., Sep 2011, In : Journal of Drug Targeting. 19, 8, p. 615-623 9 p.

Research output: Contribution to journalArticle