Research Output per year
Personal profile
General
I am currently a research fellow with the multidisciplinary Biomaterials Research Unit (BRU). My research focuses on biomaterial/host interaction studies and biocompatibility testing of existing and new biomaterials including the assessment of soft contact lenses, wound dressings and an array of new hydrogel based polymers. This post followed on from my PhD with BRU which was entitled ‘Immunological and biochemical techniques in the analysis of tear proteins’.
Prior to my PhD I took a post as a Clinical Scientist in tissue typing with the National Blood Service. In 1992 I worked in a rheumatic diseases diagnostic laboratory based in Birmingham University in conjunction with the Binding Site Ltd, as part of my MSc in Immunology. I gained my first degree in Microbiology from the University College Galway in Ireland (now NUIG) in 1991.
Research Interests
During my time at Aston University I have developed expertise in a wide range of aspects of immunological, biochemical and cell culture techniques in the characterisation of novel biomaterials, in addition to tear and wound fluid analysis. My work has focused on the identification of key immunoregulatory markers in the ocular environment in response to, the insertion and wear of, a variety hydrogel contact lens materials. I am currently interested in the determination of individual tear protein profiles by lab-a-on-chip protein sizing separation microfluidics, which can monitor the ever changing tear specifically in relation to affects of contact lens wear and ocular dysfunction on the normal tear chemistry.
Membership of Professional Bodies
- British Contact Lens Association
Contact Details
Phone number: 0121 204 3408
Email: mannam@aston.ac.uk
Room number: CE318
Education/Academic qualification
PhD
MSc
BSc, National University of Ireland Galway
External positions
Editorial Board
May 2019 → …Fingerprint Dive into the research topics where Aisling Mann is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Research Output 2002 2019
Clinical and biochemical analysis of the ageing tear film
Mann, A., Campbell, D., Mirza, Z., Hunt, O., Wolffsohn, J. S. & Tighe, B. J., 11 May 2019, In : British Journal of Ophthalmology.Research output: Contribution to journal › Article
Investigating the permeation properties of contact lenses and its influence on tear electrolyte composition
Mann, A., Sáez-martinez, V., Lydon, F. & Tighe, B., 19 Dec 2018, In : Journal of biomedical materials research: part B.Research output: Contribution to journal › Article
The potential influence of Schirmer strip variables on dry eye disease characterisation, and on tear collection and analysis
García-Porta, N., Mann, A., Sáez-Martínez, V., Franklin, V., Wolffsohn, J. S. & Tighe, B., 1 Feb 2018, In : Contact Lens and Anterior Eye. 41, 1, p. 47-53Research output: Contribution to journal › Article
The nature and consequence of vitronectin interaction in the non-compromised contact lens wearing eye
Cooner, M., Mann, A. & Tighe, B., 1 Aug 2017, In : Contact Lens and Anterior Eye. 40, 4, p. 228-235Research output: Contribution to journal › Article
Ocular biotribology and the contact lens: Surface interactions and ocular response
Mann, A. & Tighe, B. J., 21 Apr 2016, Biomaterials and regenerative medicine in ophthalmology. Chirila, T. V. & Harkin, D. G. (eds.). 2nd ed. London (UK): Woodhead, p. 45-74 30 p. (Woodhead Publishing Series in Biomaterials; no. 112).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Thesis
Biomaterial interactions with compromised tissue surfaces
Author: Cooner, M., 18 May 2015Supervisor: Tighe, B. J. (Supervisor) & Mann, A. M. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
Immunological and biochemical techniques in the analysis of tear proteins
Author: Mann, A. M., May 1998Supervisor: Tighe, B. J. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
Activities 2010 2010
- 1 Participation in workshop, seminar, course
British Contact Lens Association
Aisling Mann (Speaker)Activity: Participating in or organising an event types › Participation in workshop, seminar, course