Alan Goddard

2024

Insights into membrane interactions and their therapeutic potential

Upton, C., Healey, J., Rothnie, A. J. & Goddard, A. D., May 2024, In: Archives of Biochemistry and Biophysics. 755, 18 p., 109939.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2023

Business Teaching Beyond Silos: Interdisciplinary and Multidisciplinary Learning

Traczykowski, L. (Editor), Goddard, A. (Editor), Knight, G. (Editor) & Vettraino, E. (Editor), 14 Feb 2023, Edward Elgar. 244 p.

Research output: Book/Report › Edited Book

Embedding business skills through the bioscience placement year

Goddard, A. D., Greenhill, S. D., Rothnie, A. J., Heritage, J., Holder, L. & Gough, J. R., 10 Feb 2023, Business Teaching Beyond Silos: Interdisciplinary and Multidisciplinary Learning. Traczykowski, L., Goddard, A. D., Knight, G. & Vettraino, E. (eds.). Edward Elgar, p. 37-48 12 p.

Research output: Chapter in Book/Published conference output › Chapter

Identification of membrane engineering targets for increased butanol tolerance in Clostridium saccharoperbutylacetonicum

Linney, J. A., Routledge, S. J., Connell, S. D., Larson, T. R., Pitt, A. R., Jenkinson, E. R. & Goddard, A. D., Dec 2023, In: Biochimica et Biophysica Acta - Biomembranes. 1865, 8, 184217.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Introduction to Business Teaching Beyond Silos

Traczykowski, L., Goddard, A., Knight, G. & Vettraino, E., 10 Feb 2023, Business Teaching Beyond Silos: Interdisciplinary and Multidisciplinary Learning. Edward Elgar, p. 1-11 11 p.

Research output: Chapter in Book/Published conference output › Chapter

Membrane manipulation by free fatty acids improves microbial plant polyphenol synthesis

Tharmasothirajan, A., Melcr, J., Linney, J., Gensch, T., Krumbach, K., Ernst, K. M., Brasnett, C., Poggi, P., Pitt, A. R., Goddard, A. D., Chatgilialoglu, A., Marrink, S. J. & Marienhagen, J., 12 Sept 2023, In: Nature Communications. 14, 1, 5619.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2022

Bioinformatic characterization of a triacylglycerol lipase produced by Aspergillus flavus isolated from the decaying seed of Cucumeropsis mannii

Ezema, B. O., Omeje, K. O., Bill, R. M., Goddard, A. D., O. Eze, S. O. & Fernandez-Castane, A., 11 Feb 2022, (E-pub ahead of print) In: Journal of Biomolecular Structure and Dynamics. 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Detergent-Free Membrane Protein Purification Using SMA Polymer

Broadbent, L., Depping, P., Lodé, A., Vaitsopoulou, A., Hardy, D., Ayub, H., Mitchell-White, J., Kerr, I. D., Goddard, A. D., Bill, R. M. & Rothnie, A. J., 1 Jul 2022, Methods in Molecular Biology. Mus-Veteau, I. (ed.). Springer, Vol. 2507. p. 389-404 16 p. (Methods in Molecular Biology; vol. 2507).

Research output: Chapter in Book/Published conference output › Chapter (peer-reviewed) › peer-review

Open Access

File

Heterologous Expression of Membrane Proteins in E. coli

Depping, P., Román Lara, M. M., Kesidis, A., Bill, R. M., Rothnie, A. J., Browning, D. F. & Goddard, A. D., 1 Jul 2022, Heterologous Expression of Membrane Proteins: Methods in Molecular Biology. Mus-Veteau, I. (ed.). Springer, Vol. 2507. p. 59-78 20 p. (Methods in Molecular Biology; vol. 2507).

Research output: Chapter in Book/Published conference output › Chapter (peer-reviewed) › peer-review

Open Access

File

Membrane Protein Production in Insect Cells

Vaitsopoulou, A., Depping, P., Bill, R. M., Goddard, A. D. & Rothnie, A. J., 1 Jul 2022, Methods in Molecular Biology. Mus-Veteau, I. (ed.). Springer, Vol. 2507. p. 223-240 18 p. (Methods in Molecular Biology; vol. 2507).

Research output: Chapter in Book/Published conference output › Chapter (peer-reviewed) › peer-review

Open Access

File

Membrane Protein Production in the Yeast P. pastoris

Ayub, H., Clare, M., Broadbent, L., Simms, J., Goddard, A. D., Rothnie, A. J. & Bill, R. M., 1 Jul 2022, Methods in Molecular Biology. Mus-Veteau, I. (ed.). Springer, Vol. 2507. p. 187-199 13 p. (Methods in Molecular Biology; vol. 2507).

Research output: Chapter in Book/Published conference output › Chapter (peer-reviewed) › peer-review

2021

Adaptive response to wine selective pressures shapes the genome of a Saccharomyces interspecies hybrid

Lairón-Peris, M., Castiglioni, G. L., Routledge, S., Alonso-del-Real, J., Linney, J. A., Pitt, A. R., Melcr, J., Goddard, A. D., Barrio, E. & Querol, A., 27 Aug 2021, In: Microbial Genomics. 7, 8, 17 p., 000628.

Research output: Contribution to journal › Article › peer-review

Open Access

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Lignocellulosic biorefineries: The current state of challenges and strategies for efficient commercialization

Usmani, Z., Sharma, M., Awasthi, A. K., Lukk, T., Tuohy, M. G., Gong, L., Nguyen-Tri, P., Goddard, A. D., Bill, R. M., Nayak, S. C. & Gupta, V. K., 1 Sept 2021, In: Renewable and sustainable energy reviews. 148, 111258.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Lipid Composition Analysis Reveals Mechanisms of Ethanol Tolerance in the Model Yeast Saccharomyces cerevisiae

Lairón-Peris, M., Routledge, S. J., Linney, J. A., Alonso-Del-Real, J., Spickett, C. M., Pitt, A. R., Guillamon, J. M., Barrio, E., Goddard, A. D. & Querol, A., 26 May 2021, In: Applied and Environmental Microbiology. 87, 12, 22 p., e0044021.

Research output: Contribution to journal › Article › peer-review

Open Access

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Membrane protein extraction and purification using partially-esterified SMA polymers

Hawkins, O. P., Jahromi, C. P. T., Gulamhussein, A. A., Nestorow, S., Bahra, T., Shelton, C., Owusu-mensah, Q. K., Mohiddin, N., O'rourke, H., Ajmal, M., Byrnes, K., Khan, M., Nahar, N. N., Lim, A., Harris, C., Healy, H., Hasan, S. W., Ahmed, A., Evans, L. & Vaitsopoulou, A. & 17 others, Akram, A., Williams, C., Binding, J., Thandi, R. K., Joby, A., Guest, A., Tariq, M. Z., Rasool, F., Cavanagh, L., Kang, S., Asparuhov, B., Jestin, A., Dafforn, T. R., Simms, J., Bill, R. M., Goddard, A. D. & Rothnie, A. J., 1 Dec 2021, In: BBA -Biomembranes. 1863, 12, 183758.

Research output: Contribution to journal › Article › peer-review

Open Access

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The Novel Application of Geometric Morphometrics with Principal Component Analysis to Existing G Protein-Coupled Receptor (GPCR) Structures

Wiseman, D., Samra, N., Román Lara, M. M., Penrice, S. C. & Goddard, A., 23 Sept 2021, In: Pharmaceuticals. 14, 10, 953.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2020

Biophysical analysis of lipidic nanoparticles

Rozo, A. J., Cox, M. H., Devitt, A., Rothnie, A. J. & Goddard, A. D., 1 Aug 2020, In: Methods. 180, p. 45-55 11 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

Expression and purification of recombinant G protein-coupled receptors: A review

Wiseman, D. N., Otchere, A., Patel, J. H., Uddin, R., Pollock, N. L., Routledge, S. J., Rothnie, A. J., Slack, C., Poyner, D. R., Bill, R. M. & Goddard, A. D., 1 Mar 2020, In: Protein Expression and Purification. 167, 105524.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Expression of eukaryotic membrane proteins in eukaryotic and prokaryotic hosts

Kesidis, A., Depping, P., Lodé, A., Vaitsopoulou, A., Bill, R. M., Goddard, A. D. & Rothnie, A. J., 1 Aug 2020, In: Methods. 180, p. 3-18 16 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

Membrane Protein Function

Goddard, A., Román Lara, M. M., Depping, P., Oates, J. & Watts, A., 15 Jul 2020, Encyclopedia of Biophysics. Roberts, G. & Watts, A. (eds.). Springer, p. 1-7 7 p.

Research output: Chapter in Book/Published conference output › Entry for encyclopedia/dictionary

Open Access

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Membrane Proteins: Structure and Organization

Goddard, A. D., Linney, J. A., Rozo, A. J., Oates, J. & Watts, A., 28 Jun 2020, Encyclopedia of Biophysics. Roberts, G. & Watts, A. (eds.). Springer, p. 1-4 4 p.

Research output: Chapter in Book/Published conference output › Entry for encyclopedia/dictionary

Open Access

File

2019

Liposomes as models for membrane integrity

Routledge, S. J., Linney, J. A. & Goddard, A. D., 28 Jun 2019, In: Biochemical Society Transactions. 47, 3, p. 919-932 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

2018

Dynamic tuneable G protein-coupled receptor monomer-dimer populations

Dijkman, P. M., Castell, O. K., Goddard, A., Munoz-Garcia, J. C., de Graaf, C., Wallace, M. I. & Watts, A., 27 Apr 2018, In: Nature Communications. 9, 1710.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Mechanistic and phenotypic studies of bicarinalin, BP100 and colistin action on Acinetobacter baumannii

Eales, M. G., Ferrari, E., Goddard, A., Lancaster, L., Sanderson, P. & Miller, C., Jul 2018, In: Research in Microbiology. 169, 6, p. 296-302 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Recombinant Membrane Protein Methods

Bill, R. M., Goddard, A. D. & Rothnie, A. J., 1 Sept 2018, In: Methods. 147, p. 1-2 2 p.

Research output: Contribution to journal › Editorial

Single molecule fluorescence for membrane proteins

Castell, O. K., Dijkman, P. M., Wiseman, D. & Goddard, A., 1 Sept 2018, In: Methods. 147, p. 221-228 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2017

Neurotensin receptor 1 facilitates intracellular and transepithelial delivery of macromolecules

Bird, J. L., Simpson, R., Vllasaliu, D. & Goddard, A. D., 1 Oct 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 119, p. 300-309 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

The Paracoccus denitrificans NarK-like nitrate and nitrite transporters—probing nitrate uptake and nitrate/nitrite exchange mechanisms

Goddard, A. D., Bali, S., Mavridou, D. A. I., Luque-Almagro, V. M., Gates, A. J., Roldán, M. D., Newstead, S., Richardson, D. J. & Ferguson, S. J., Jan 2017, In: Molecular Microbiology. 103, 1, p. 117-133 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2015

Reconstitution of membrane proteins: a GPCR as an example

Goddard, A. D., Dijkman, P. M., Adamson, R. J., dos Reis, R. I. & Watts, A., 2015, In: Methods in Enzymology. 556, p. 405-424 20 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

2013

Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists

Basu, S., Leonard, J. C., Desai, N., Mavridou, D. A. I., Tang, K. H., Goddard, A. D., Ginger, M. L., Lukeš, J. & Allen, J. W. A., Feb 2013, In: Eukaryotic Cell. 12, 2, p. 343-355 13 p.

Research output: Contribution to journal › Article › peer-review

Lipid-dependent GPCR dimerization

Goddard, A. D., Dijkman, P. M., Adamson, R. J. & Watts, A., 2013, Receptor-receptor interactions. Conn, P. M. (ed.). London (UK): Academic Press, Vol. 117. p. 341-357 17 p. (Methods in Cell Biology; vol. 117).

Research output: Chapter in Book/Published conference output › Chapter (peer-reviewed) › peer-review

2012

Contributions of fluorescence techniques to understanding G protein-coupled receptor dimerisation

Goddard, A. D. & Watts, A., Dec 2012, In: Biophysical Reviews. 4, 4, p. 291-298 8 p.

Research output: Contribution to journal › Review article › peer-review

Regulation of G protein-coupled receptors by palmitoylation and cholesterol

Goddard, A. D. & Watts, A., 19 Mar 2012, In: BMC Biology. 10, 3 p., 27.

Research output: Contribution to journal › Letter, comment/opinion or interview › peer-review

Open Access

File

2011

A composite biochemical system for bacterial nitrate and nitrite assimilation as exemplified by Paracoccus denitrificans

Gates, A. J., Luque-Almagro, V. M., Goddard, A. D., Ferguson, S. J., Roldán, M. D. & Richardson, D. J., 1 May 2011, In: Biochemical Journal. 435, 3, p. 743-753 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Cytochrome c biogenesis System I

Stevens, J. M., Mavridou, D. A. I., Hamer, R., Kritsiligkou, P., Goddard, A. D. & Ferguson, S. J., Nov 2011, In: FEBS journal. 278, 22, p. 4170-4178 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2010

Comparing the substrate specificities of cytochrome c biogenesis Systems I and II

Goddard, A. D., Stevens, J. M., Rondelet, A., Nomerotskaia, E., Allen, J. W. A. & Ferguson, S. J., Feb 2010, In: FEBS journal. 277, 3, p. 726-737 12 p.

Research output: Contribution to journal › Article › peer-review

c-Type cytochrome biogenesis can occur via a natural Ccm system lacking CcmH, CcmG, and the heme-binding histidine of CcmE

Goddard, A. D., Stevens, J. M., Rao, F., Mavridou, D. A. I., Chan, W., Richardson, D. J., Allen, J. W. A. & Ferguson, S. J., 23 Jul 2010, In: Journal of Biological Chemistry. 285, 30, p. 22882-22889 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2009

Control of periplasmic interdomain thiol: disulfide exchange in the transmembrane oxidoreductase DsbD

Mavridou, D. A. I., Stevens, J. M., Goddard, A. D., Willis, A. C., Ferguson, S. J. & Redfield, C., 30 Jan 2009, In: Journal of Biological Chemistry. 284, 5, p. 3219-3226 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

The cationic region of Rhes mediates its interactions with specific Gβ subunits

Hill, C., Goddard, A., Ladds, G. & Davey, J., Feb 2009, In: Cellular Physiology and Biochemistry. 23, 1-3, p. 1-8 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2008

Interdependence of two NarK domains in a fused nitrate/nitrite transporter

Goddard, A. D., Moir, J. W. B., Richardson, D. J. & Ferguson, S. J., Nov 2008, In: Molecular Microbiology. 70, 3, p. 667-681 15 p.

Research output: Contribution to journal › Article › peer-review

2007

Differential effects of RGS proteins on Gαq and Gα11 activity

Ladds, G., Goddard, A., Hill, C., Thornton, S. & Davey, J., 1 Jan 2007, In: Cellular Signalling. 19, 1, p. 103-113 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2006

Identification of Gnr1p, a negative regulator of Gα signalling in Schizosaccharomyces pombe, and its complementation by human Gβ subunits

Goddard, A., Ladds, G., Forfar, R. & Davey, J., Dec 2006, In: Fungal Genetics and Biology. 43, 12, p. 840-851 12 p.

Research output: Contribution to journal › Article › peer-review

Investigating RGS proteins in yeast

Hill, C., Goddard, A., Davey, J. & Ladds, G., Jun 2006, In: Seminars in Cell and Developmental Biology. 17, 3, p. 352-362 11 p.

Research output: Contribution to journal › Review article › peer-review

2005

Development of a semi-quantitative plate-based α-galactosidase gene reporter for Schizosaccharomyces pombe and its use to isolate a constitutively active Mam2

Goddard, A., Ladds, G. & Davey, J., 15 Jan 2005, In: Yeast. 22, 1, p. 31-41 11 p.

Research output: Contribution to journal › Article › peer-review

Functional analysis of heterologous GPCR signalling pathways in yeast

Ladds, G., Goddard, A. & Davey, J., Jul 2005, In: Trends in Biotechnology. 23, 7, p. 367-373 7 p.

Research output: Contribution to journal › Review article › peer-review

Professor Alan Goddard

Research output

Search results