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Andrew Devitt

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Andrew Devitt

Prof, Professor

 https://orcid.org/0000-0002-4651-6761

    • United Kingdom

    Personal profile

    Contact Details

    email: [email protected] 
    tel:     +44 (0) 121 204 4165 
    fax:     +44 (0) 121 204 4187
    Book an appointment here

    Research Interests

    As an inflammatory cell biologist, my research over 20 years has focused on the innate immune system and its role in protection and tissue repair through the study of phagocyte clearance of dying (apoptotic) cells and microbial challenge. Research within my research group addresses membrane receptors/ligands and cell communication in this phagocytic clearance process.  Current work aims to define the mechanisms by which apoptotic cells communicate via extracellular vesicles (EV).  This BBSRC-funded work is revealing novel EV structure-function relationships that underpin tissue repair and regeneration capacity of EV from both apoptotic and viable cells, including mesenchymal stem cells.  This research has introduced the concept that EV are an active extracellular metabolic compartment capable of modulating inflammation.  The ultimate aim of my group’s research is to modify inflammation for therapeutic gain either through the inhibition of inflammation (e.g. in cardiovascular disease and regenerative medicine applications) or promoting inflammation (e.g. in tumours).

    Teaching Activity

    Undergraduate:

    Year 2 (level 5) Immunology & microbiology

    Year F (level 6) Immunology

    Postgraduate:

    Level 7 Immunology and Cell Biology

    Employment

    Membership of Professional Bodies

    • Fellow of the Royal Society of Biology
    • Fellow of the Higher Education Academy 
    • Member - UKEV: UK Extracellular Vesicle Society
    • Member - British Society for Immunology
    • Member - International Society for Extracellular Vesicles
    • Member - The Biochemical Society 
    • Member - The Society For Leukocyte Biology 
    • Member - European Cell Death Organization

    Education/Academic qualification

    PhD, Host cell responses to chlamydial infection, University of Birmingham

    Award Date: 1 Jun 1995

    BSc, Microbiology, University of Manchester

    Award Date: 1 Jul 1991

    External positions

    Member -Dunhill Medical Trust Research Grants Committee, The Dunhill Medical Trust

    Chair BBSRC Committee A, UKRI-BBSRC

    External Examiner, University of Edinburgh

    External Examiner, York St John, York St John University

    Keywords

    • QR180 Immunology
    • Intercellular Communication
    • Extracellular Vesicles (EV)

    Expertise related to UN Sustainable Development Goals

    In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being
    2. SDG 12 - Responsible Consumption and Production
      SDG 12 Responsible Consumption and Production

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