19982019

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2019

Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein

Teo, A. C. K., Lee, S. C., Pollock, N. L., Stroud, Z., Hall, S., Thakker, A., Pitt, A. R., Dafforn, T. R., Spickett, C. M. & Roper, D. I., 12 Feb 2019, In : Scientific Reports. 9, 1, 1813.

Research output: Contribution to journalArticle

Open Access
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Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies

Campos-pinto, I., Méndez, L., Schouten, J., Wilkins, J., Fedorova, M., Pitt, A., Davis, P. & Spickett, C., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 234-244 11 p.

Research output: Contribution to journalArticle

Open Access
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Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS

Ni, Z., Sousa, B. C., Colombo, S., Afonso, C. B., Melo, T., Pitt, A. R., Spickett, C. M., Domingues, P., Domingues, M. R., Fedorova, M. & Criscuolo, A., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 156-166 11 p.

Research output: Contribution to journalArticle

Open Access
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Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration

Rossin, D., Dias, I. H. K., Solej, M., Milic, I., Pitt, A. R., Iaia, N., Scoppapietra, L., Devitt, A., Nano, M., Degiuli, M., Volante, M., Caccia, C., Leoni, V., Griffiths, H. R., Spickett, C. M., Poli, G. & Biasi, F., 20 May 2019, In : Free Radical Biology and Medicine. 136, p. 35-44 10 p.

Research output: Contribution to journalArticle

Open Access
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PARP1 Co-regulates EP300–BRG1-dependent transcription of genes involved in breast cancer cell proliferation and DNA repair

Sobczak, M., Pitt, A. R., Spickett, C. M. & Robaszkiewicz, A., 11 Oct 2019, In : Cancers. 11, 10, 1539.

Research output: Contribution to journalArticle

Open Access
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Short-chain lipid peroxidation products form covalent adducts with pyruvate kinase and inhibit its activity in vitro and in breast cancer cells

Costa Sousa, B., Ahmed, T., Dann, W. L., Ashman, J., Guy, A., Durand, T., Pitt, A. R. & Spickett, C. M., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 223-233 11 p.

Research output: Contribution to journalArticle

Open Access
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2018

A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells

Knight, A. R., Taylor, E., Lukaszewski, R., Tveen Jensen, K., Jones, H. E., Carré, J. E., supov, M. N. I., Littlechild, J. A., Bailey, S. J., Brewer, E., McDonald, T. J., Pitt, A. R., Spickett, C. M. & Winyard, P. G., 20 May 2018, In : Free Radical Biology and Medicine. 120, p. 246-254

Research output: Contribution to journalArticle

Open Access
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Open Access
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Open Access
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2017
Open Access
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Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162]

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçin, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., 26 Oct 2017, In : Redox Biology. In press

Research output: Contribution to journalArticle

Open Access
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European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST Action BM1203 (EU-ROS)

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec–butuner, B., Dias, I., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L-O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K-H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., Mcbean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P-A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., di Lisa, F. & Daiber, A., 1 Oct 2017, In : Redox biology. 13, p. 94-162 69 p.

Research output: Contribution to journalArticle

Open Access
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2016
Open Access
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2015

Interfacing low-energy SAW nebulization with liquid chromatography-mass spectrometry for the analysis of biological samples

Tveen Jensen, K., Gesellchen, F., Wilson, R., Spickett, C., Cooper, J. M. & Pitt, A., 15 May 2015, In : Scientific Reports. 5, 5 p., 9736.

Research output: Contribution to journalArticle

Open Access
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Open Access
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Top-down lipidomics of low density lipoprotein reveal altered lipid profiles in advanced chronic kidney disease

Reis, A., Rudnitskaya, A., Chariyavilaskul, P., Dhaun, N., Melville, V., Goddard, J., Webb, D. J., Pitt, A. R. & Spickett, C. M., 1 Feb 2015, In : Journal of Lipid Research. 56, 2, p. 413-422 10 p.

Research output: Contribution to journalArticle

Open Access
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2014

Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH

Maciel, E., Neves, B. M., Santinha, D., Reis, A., Domingues, P., Cruz, M. T., Pitt, A. R., Spickett, C. M. & Domingues, M. R. M., 15 Apr 2014, In : Archives of Biochemistry and Biophysics. 548, p. 38–45 8 p.

Research output: Contribution to journalArticle

Open Access
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HOCl-modified phosphatidylcholines induce apoptosis and redox imbalance in HUVEC-ST cells

Robaszkiewicz, A., Bartosz, G., Pitt, A. R., Thakker, A., Armstrong, R. A., Spickett, C. M. & Soszyński, M., 15 Apr 2014, In : Archives of Biochemistry and Biophysics. 548, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
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Identification and relative quantification of tyrosine nitration in a model peptide using two-dimensional infrared spectroscopy

Rezende Valim, L., Davies, J. A., Tveen Jensen, K., Guo, R., Willison, K. R., Spickett, C. M., Pitt, A. R. & Klug, D. R., 13 Nov 2014, In : Journal of Physical Chemistry: Part B. 118, 45, p. 12855-12864 10 p.

Research output: Contribution to journalArticle

Open Access
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Magnetite-doped polydimethylsiloxane (PDMS) for phosphopeptide enrichment

Sandison, M. E., Tveen Jensen, K., Gesellchen, F., Cooper, J. M. & Pitt, A. R., 7 Oct 2014, In : Analyst. 139, 19, p. 4974-4981 8 p.

Research output: Contribution to journalArticle

Open Access
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Quantification of functionalised gold nanoparticle-targeted knockdown of gene expression in HeLa cells

Jiwaji, M., Sandison, M. E., Reboud, J., Stevenson, R., Daly, R., Barkess, G., Faulds, K., Kolch, W., Graham, D., Girolami, M. A., Cooper, J. M. & Pitt, A., 13 Jun 2014, In : PLoS ONE. 9, 6, 10 p., e99458.

Research output: Contribution to journalArticle

Open Access
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2013

A comparison of five lipid extraction solvent systems for lipidomic studies of human LDL

Reis, A., Rudnitskaya, A., Blackburn, G. J., Fauzi, N. M., Pitt, A. R. & Spickett, C. M., Jul 2013, In : Journal of Lipid Research. 54, 7, p. 1812-1824 13 p.

Research output: Contribution to journalArticle

2012

Eukaryotic translation initiation factor 3, subunit a, regulates the extracellular signal-regulated kinase pathway

Xu, T-R., Lu, R-F., Romano, D., Pitt, A., Houslay, M. D., Milligan, G. & Kolch, W., Jan 2012, In : Molecular and Cellular Biology. 32, 1, p. 88-95 8 p.

Research output: Contribution to journalArticle

Open Access

Generation of primary hepatocyte microarrays by piezoelectric printing

Zarowna-Dabrowska, A., McKenna, E. O., Schütte, M. E., Glidle, A., Chen, L., Cuestas-Ayllon, C., Marshall, D., Pitt, A., Dawson, M. D., Gu, E., Cooper, J. M. & Yin, H., 1 Jan 2012, In : Colloids and Surface B: Biointerfaces. 89, 1, p. 126-132 7 p.

Research output: Contribution to journalArticle

Protein oxidation: role in signalling and detection by mass spectrometry

Spickett, C. M. & Pitt, A. R., Jan 2012, In : Amino Acids. 42, 1, p. 5-21 17 p.

Research output: Contribution to journalArticle

Shaping acoustic fields as a toolset for microfluidic manipulations in diagnostic technologies

Reboud, J., Bourquin, Y., Wilson, R., Pall, G. S., Jiwaji, M., Pitt, A. R., Graham, A., Waters, A. P. & Cooper, J. M., 18 Sep 2012, In : Proceedings of the National Academy of Sciences. 109, 38, p. 15162-15167 6 p.

Research output: Contribution to journalArticle

Open Access

Unique reporter-based sensor platforms to monitor signalling in cells

Jiwaji, M., Daly, R., Gibriel, A., Barkess, G., McLean, P., Yang, J., Pansare, K., Cumming, S. A., McLauchlan, A., Kamola, P. J., Bhutta, M. S., West, A. G., West, K. L., Kolch, W., Girolami, M. A. & Pitt, A. R., 29 Nov 2012, In : PLoS ONE. 7, 11, 10 p., e50521.

Research output: Contribution to journalArticle

File
2011

Intracellular protein determination using droplet-based immunoassays

Martino, C., Zagnoni, M., Sandison, M. E., Chanasakulniyom, M., Pitt, A. & Cooper, J. M., 16 May 2011, In : Analytical Chemistry. 83, 13, p. 5361-5368 8 p.

Research output: Contribution to journalArticle

Open Access

Matrix-free mass spectrometric imaging using laser desorption ionisation Fourier transform ion cyclotron resonance mass spectrometry

Goodwin, R. J. A., Pitt, A. R., Harrison, D., Weidt, S. K., Langridge-Smith, P. R. R., Barrett, M. P. & Mackay, C. L., 15 Apr 2011, In : Rapid communications in mass spectrometry. 25, 7, p. 969-72 4 p.

Research output: Contribution to journalArticle

Open Access

Microscale mesoarrays created by dip-pen nanolithography for screening of protein-protein interactions

Thompson, D. G., McKenna, E. O., Pitt, A. & Graham, D., 15 Aug 2011, In : Biosensors and Bioelectronics. 26, 12, p. 4667-4673 7 p.

Research output: Contribution to journalArticle

Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3β

Al-Mulla, F., Bitar, M. S., Al-Maghrebi, M., Behbehani, A. I., Al-Ali, W., Rath, O., Doyle, B., Tan, K. Y., Pitt, A. & Kolch, W., 15 Feb 2011, In : Cancer Research. 71, 4, p. 1334-1343 10 p.

Research output: Contribution to journalArticle

The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Li, Y., McKenna, E. O., Parkes, W., Pitt, A. R. & Walton, A. J., 15 Aug 2011, In : Applied Physics Letters. 99, 7, 3 p., 073703.

Research output: Contribution to journalArticle

Open Access
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2010

A solvent-free matrix application method for matrix-assisted laser desorption/ionization imaging of small molecules

Goodwin, R. J., Macintyre, L., Watson, D. G., Scullion, S. P. & Pitt, A., 15 Jun 2010, In : Rapid communications in mass spectrometry. 24, 11, p. 1682-1686 5 p.

Research output: Contribution to journalArticle

Comprehensive human urine standards for comparability and standardization in clinical proteome analysis

Mischak, H., Kolch, W., Aivaliotis, M., Bouyssié, D., Court, M., Dihazi, H., Dihazi, G. H., Franke, J., Garin, J., Gonzalez de Peredo, A., Iphöfer, A., Jänsch, L., Lacroix, C., Makridakis, M., Masselon, C., Metzger, J., Monsarrat, B., Mrug, M., Norling, M., Novak, J. & 11 others, Pich, A., Pitt, A., Bongcam-Rudloff, E., Siwy, J., Suzuki, H., Thongboonkerd, V., Wang, L-S., Zoidakis, J., Zürbig, P., Schanstra, J. P. & Vlahou, A., Apr 2010, In : Proteomics. 4, 4, p. 464-78 15 p.

Research output: Contribution to journalArticle

Effect of phosphatidylcholine chlorohydrins on human erythrocytes

Robaszkiewicz, A., Greig, F. H., Pitt, A. R., Spickett, C. M., Bartosz, G. & Soszyński, M., Sep 2010, In : Chemistry and Physics of Lipids. 163, 7, p. 639-647 9 p.

Research output: Contribution to journalArticle

Mass spectrometry imaging of pharmacological compounds in tissue sections

Goodwin, R. J. A. & Pitt, A. R., Feb 2010, In : Bioanalysis. 2, 2, p. 279-293 15 p.

Research output: Contribution to journalArticle

On-chip immunoprecipitation for protein purification

Sandison, M. E., Cumming, S. A., Kolch, W. & Pitt, A. R., 17 Aug 2010, In : Lab on a Chip. 2010, 20, p. 2805-2813 9 p.

Research output: Contribution to journalArticle

Stopping the clock on proteomic degradation by heat treatment at the point of tissue excision

Goodwin, R. J. A., Lang, A. M., Allingham, H., Borén, M. & Pitt, A. R., 9 May 2010, In : Proteomics. 10, 9, p. 1751-1761 11 p.

Research output: Contribution to journalArticle

The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier

Sturm, O. E., Orton, R., Grindlay, J., Birtwistle, M., Vyshemirsky, V., Gilbert, D., Calder, M., Pitt, A., Kholodenko, B. & Kolch, W., 21 Dec 2010, In : Science Signaling. 3, 153, p. ra90

Research output: Contribution to journalArticle

Open Access

The Renilla luciferase gene as a reference gene for normalization of gene expression in transiently transfected cells

Jiwaji, M., Daly, R., Pansare, K., McLean, P., Yang, J., Kolch, W. & Pitt, A., 31 Dec 2010, In : BMC Molecular Biology. 11, p. 103

Research output: Contribution to journalArticle

Open Access
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2009

Development of novel mass spectrometric methods for identifying HOCl-induced modifications to proteins

Mouls, L., Silajdzic, E., Haroune, N., Spickett, C. M. & Pitt, A. R., 1 Mar 2009, In : Proteomics. 9, 6, p. 1617-1631 15 p.

Research output: Contribution to journalArticle

Performance of five different electrospray ionisation sources in conjunction with rapid monolithic column liquid chromatography and fast MS/MS scanning

Burgess, K. E. V., Lainson, A., Imrie, L., Fraser-Pitt, D., Yaga, R., Smith, D. G. E., Swart, R., Pitt, A. R. & Inglis, N. F., Mar 2009, In : Proteomics. 9, 6, p. 1720-1726 7 p.

Research output: Contribution to journalArticle

The C-terminus of Raf-1 acts as a 14-3-3-dependent activation switch

Dhillon, A. S., Yip, Y. Y., Grindlay, G. J., Pakay, J. L., Dangers, M., Hillmann, M., Clark, W., Pitt, A., Mischak, H. & Kolch, W., Nov 2009, In : Cellular Signalling. 21, 11, p. 1645-1651 7 p.

Research output: Contribution to journalArticle

2008

Characterisation of the plasma membrane subproteome of bloodstream form Trypanosoma brucei

Bridges, D. J., Pitt, A. R., Hanrahan, O., Brennan, K., Voorheis, H. P., Herzyk, P., de Koning, H. P. & Burchmore, R. J. S., Jan 2008, In : Proteomics. 8, 1, p. 83-99 17 p.

Research output: Contribution to journalArticle