19982019
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Research Output 1998 2019

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2019

Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein

Teo, A. C. K., Lee, S. C., Pollock, N. L., Stroud, Z., Hall, S., Thakker, A., Pitt, A. R., Dafforn, T. R., Spickett, C. M. & Roper, D. I., 12 Feb 2019, In : Scientific Reports. 9, 1, 1813.

Research output: Contribution to journalArticle

Open Access
File
Bacterial Proteins
Phospholipids
Membrane Proteins
Lipids
Styrene

Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies

Campos-pinto, I., Méndez, L., Schouten, J., Wilkins, J., Fedorova, M., Pitt, A., Davis, P. & Spickett, C., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 234-244 11 p.

Research output: Contribution to journalArticle

Open Access
File
Epitope Mapping
Serum Albumin
Epitopes
Antibodies
Peptides

Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS

Ni, Z., Sousa, B. C., Colombo, S., Afonso, C. B., Melo, T., Pitt, A. R., Spickett, C. M., Domingues, P., Domingues, M. R., Fedorova, M. & Criscuolo, A., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 156-166 11 p.

Research output: Contribution to journalArticle

Open Access
File
Air
Lipids
Lipid Peroxidation
Oxidation
Arachidonic Acids

Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration

Rossin, D., Dias, I. H. K., Solej, M., Milic, I., Pitt, A. R., Iaia, N., Scoppapietra, L., Devitt, A., Nano, M., Degiuli, M., Volante, M., Caccia, C., Leoni, V., Griffiths, H. R., Spickett, C. M., Poli, G. & Biasi, F., 20 May 2019, In : Free Radical Biology and Medicine. 136, p. 35-44 10 p.

Research output: Contribution to journalArticle

Infiltration
Colorectal Neoplasms
Cell Survival
Cells
Tumors

PARP1 Co-regulates EP300–BRG1-dependent transcription of genes involved in breast cancer cell proliferation and DNA repair

Sobczak, M., Pitt, A. R., Spickett, C. M. & Robaszkiewicz, A., 11 Oct 2019, In : Cancers. 11, 10, 1539.

Research output: Contribution to journalArticle

Open Access
File
DNA Repair
Cell Proliferation
Breast Neoplasms
Genes
Adenosine Diphosphate

Short-chain lipid peroxidation products form covalent adducts with pyruvate kinase and inhibit its activity in vitro and in breast cancer cells

Costa Sousa, B., Ahmed, T., Dann, W. L., Ashman, J., Guy, A., Durand, T., Pitt, A. R. & Spickett, C. M., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 223-233 11 p.

Research output: Contribution to journalArticle

Open Access
File
Pyruvate Kinase
Aldehydes
Lipid Peroxidation
Cells
Breast Neoplasms
2018

A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells

Knight, A. R., Taylor, E., Lukaszewski, R., Tveen Jensen, K., Jones, H. E., Carré, J. E., supov, M. N. I., Littlechild, J. A., Bailey, S. J., Brewer, E., McDonald, T. J., Pitt, A. R., Spickett, C. M. & Winyard, P. G., 20 May 2018, In : Free Radical Biology and Medicine. 120, p. 246-254

Research output: Contribution to journalArticle

Open Access
File
Immunosorbents
Oxidative stress
Biomarkers
Assays
Blood Cells
Open Access
File
Acrolein
Aldehydes
Mass spectrometry
Mass Spectrometry
Muramidase
Open Access
File
Hypochlorous Acid
Phosphoric Monoester Hydrolases
Oxidation
Tyrosine
Proteins
2017
Open Access
File
Aldehydes
Lipids
Oxidation
Phospholipids
2-butenal

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162]

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçin, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., 26 Oct 2017, In : Redox Biology. In press

Research output: Contribution to journalArticle

Open Access
File

European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST Action BM1203 (EU-ROS)

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec–butuner, B., Dias, I., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L-O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K-H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., Mcbean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P-A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., di Lisa, F. & Daiber, A., 1 Oct 2017, In : Redox biology. 13, p. 94-162 69 p.

Research output: Contribution to journalArticle

Open Access
File
Reactive Nitrogen Species
Oxidation-Reduction
Oxidative stress
Technology
Reactive Oxygen Species
2016
Open Access
File
Phosphoric Monoester Hydrolases
Oxidation
Oxidation-Reduction
Proteins
Dual-Specificity Phosphatases
2015

Interfacing low-energy SAW nebulization with liquid chromatography-mass spectrometry for the analysis of biological samples

Tveen Jensen, K., Gesellchen, F., Wilson, R., Spickett, C., Cooper, J. M. & Pitt, A., 15 May 2015, In : Scientific Reports. 5, 5 p., 9736.

Research output: Contribution to journalArticle

Open Access
File
Liquid chromatography
Surface waves
Mass spectrometry
Mass spectrometers
Acoustic waves
Open Access
File
Physiology
Pathology
Mass spectrometry
Mass Spectrometry
Phospholipids

Top-down lipidomics of low density lipoprotein reveal altered lipid profiles in advanced chronic kidney disease

Reis, A., Rudnitskaya, A., Chariyavilaskul, P., Dhaun, N., Melville, V., Goddard, J., Webb, D. J., Pitt, A. R. & Spickett, C. M., 1 Feb 2015, In : Journal of Lipid Research. 56, 2, p. 413-422 10 p.

Research output: Contribution to journalArticle

Open Access
File
Chronic Renal Insufficiency
LDL Lipoproteins
Lipids
Ethanolamines
Sulfoglycosphingolipids
2014

Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH

Maciel, E., Neves, B. M., Santinha, D., Reis, A., Domingues, P., Cruz, M. T., Pitt, A. R., Spickett, C. M. & Domingues, M. R. M., 15 Apr 2014, In : Archives of Biochemistry and Biophysics. 548, p. 38–45 8 p.

Research output: Contribution to journalArticle

Open Access
File
Phosphatidylserines
Keratinocytes
Oxidation
Serine
Derivatives

HOCl-modified phosphatidylcholines induce apoptosis and redox imbalance in HUVEC-ST cells

Robaszkiewicz, A., Bartosz, G., Pitt, A. R., Thakker, A., Armstrong, R. A., Spickett, C. M. & Soszyński, M., 15 Apr 2014, In : Archives of Biochemistry and Biophysics. 548, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
File
Human Umbilical Vein Endothelial Cells
Phosphatidylcholines
Oxidation-Reduction
Caspase 7
Phospholipids

Identification and relative quantification of tyrosine nitration in a model peptide using two-dimensional infrared spectroscopy

Rezende Valim, L., Davies, J. A., Tveen Jensen, K., Guo, R., Willison, K. R., Spickett, C. M., Pitt, A. R. & Klug, D. R., 27 Oct 2014, In : Journal of Physical Chemistry: Part B. 118, 45, p. 12855-12864 10 p.

Research output: Contribution to journalArticle

Open Access
File
nitration
Nitration
tyrosine
Peptides
peptides

Magnetite-doped polydimethylsiloxane (PDMS) for phosphopeptide enrichment

Sandison, M. E., Tveen Jensen, K., Gesellchen, F., Cooper, J. M. & Pitt, A. R., 7 Oct 2014, In : Analyst. 139, 19, p. 4974-4981 8 p.

Research output: Contribution to journalArticle

Open Access
File
Ferrosoferric Oxide
Phosphopeptides
Phosphorylation
Magnetite
Polydimethylsiloxane

Quantification of functionalised gold nanoparticle-targeted knockdown of gene expression in HeLa cells

Jiwaji, M., Sandison, M. E., Reboud, J., Stevenson, R., Daly, R., Barkess, G., Faulds, K., Kolch, W., Graham, D., Girolami, M. A., Cooper, J. M. & Pitt, A., 13 Jun 2014, In : PLoS ONE. 9, 6, 10 p., e99458.

Research output: Contribution to journalArticle

Open Access
File
single-stranded DNA
transfection
HeLa Cells
Gene expression
Gold
2013

A comparison of five lipid extraction solvent systems for lipidomic studies of human LDL

Reis, A., Rudnitskaya, A., Blackburn, G. J., Fauzi, N. M., Pitt, A. R. & Spickett, C. M., Jul 2013, In : Journal of Lipid Research. 54, 7, p. 1812-1824 13 p.

Research output: Contribution to journalArticle

Solvent extraction
Lipids
2-Propanol
Hexanes
oxidized low density lipoprotein
Mass spectrometry
Mass Spectrometry
Ions
Proteins
Oxidation
LDL Lipoproteins
Glycosylation
Ions
Proteins
Biomarkers
2012

Eukaryotic translation initiation factor 3, subunit a, regulates the extracellular signal-regulated kinase pathway

Xu, T-R., Lu, R-F., Romano, D., Pitt, A., Houslay, M. D., Milligan, G. & Kolch, W., Jan 2012, In : Molecular and Cellular Biology. 32, 1, p. 88-95 8 p.

Research output: Contribution to journalArticle

Open Access
Prokaryotic Initiation Factor-3
Eukaryotic Initiation Factor-3
Eukaryotic Initiation Factors
Extracellular Signal-Regulated MAP Kinases
Epidermal Growth Factor

Generation of primary hepatocyte microarrays by piezoelectric printing

Zarowna-Dabrowska, A., McKenna, E. O., Schütte, M. E., Glidle, A., Chen, L., Cuestas-Ayllon, C., Marshall, D., Pitt, A., Dawson, M. D., Gu, E., Cooper, J. M. & Yin, H., 1 Jan 2012, In : Colloids and Surface B: Biointerfaces. 89, 1, p. 126-132 7 p.

Research output: Contribution to journalArticle

Printing
collagens
Microarrays
Collagen
printing

Protein oxidation: role in signalling and detection by mass spectrometry

Spickett, C. M. & Pitt, A. R., Jan 2012, In : Amino Acids. 42, 1, p. 5-21 17 p.

Research output: Contribution to journalArticle

Post Translational Protein Processing
Mass spectrometry
Mass Spectrometry
Disulfides
Oxidation

Shaping acoustic fields as a toolset for microfluidic manipulations in diagnostic technologies

Reboud, J., Bourquin, Y., Wilson, R., Pall, G. S., Jiwaji, M., Pitt, A. R., Graham, A., Waters, A. P. & Cooper, J. M., 18 Sep 2012, In : Proceedings of the National Academy of Sciences. 109, 38, p. 15162-15167 6 p.

Research output: Contribution to journalArticle

Open Access
Microfluidics
Acoustics
Technology
Ultrasonics
Polymerase Chain Reaction

Unique reporter-based sensor platforms to monitor signalling in cells

Jiwaji, M., Daly, R., Gibriel, A., Barkess, G., McLean, P., Yang, J., Pansare, K., Cumming, S. A., McLauchlan, A., Kamola, P. J., Bhutta, M. S., West, A. G., West, K. L., Kolch, W., Girolami, M. A. & Pitt, A. R., 29 Nov 2012, In : PLoS ONE. 7, 11, 10 p., e50521.

Research output: Contribution to journalArticle

File
Transcription Factors
transcription factors
monitoring
Transcriptional Activation
Sensors
2011
Electrospray ionization
Electrospray Ionization Mass Spectrometry
Mass spectrometry
Phospholipids
Oxidation

Intracellular protein determination using droplet-based immunoassays

Martino, C., Zagnoni, M., Sandison, M. E., Chanasakulniyom, M., Pitt, A. & Cooper, J. M., 16 May 2011, In : Analytical Chemistry. 83, 13, p. 5361-5368 8 p.

Research output: Contribution to journalArticle

Open Access
Proteins
Actins
Suspensions
Oils
Water

Matrix-free mass spectrometric imaging using laser desorption ionisation Fourier transform ion cyclotron resonance mass spectrometry

Goodwin, R. J. A., Pitt, A. R., Harrison, D., Weidt, S. K., Langridge-Smith, P. R. R., Barrett, M. P. & Mackay, C. L., 15 Apr 2011, In : Rapid communications in mass spectrometry. 25, 7, p. 969-72 4 p.

Research output: Contribution to journalArticle

Open Access
Cyclotron resonance
Ionization
Mass spectrometry
Desorption
Fourier transforms

Microscale mesoarrays created by dip-pen nanolithography for screening of protein-protein interactions

Thompson, D. G., McKenna, E. O., Pitt, A. & Graham, D., 15 Aug 2011, In : Biosensors and Bioelectronics. 26, 12, p. 4667-4673 7 p.

Research output: Contribution to journalArticle

Nanolithography
Screening
Proteins
Microarrays
Protein Array Analysis

Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3β

Al-Mulla, F., Bitar, M. S., Al-Maghrebi, M., Behbehani, A. I., Al-Ali, W., Rath, O., Doyle, B., Tan, K. Y., Pitt, A. & Kolch, W., 15 Feb 2011, In : Cancer Research. 71, 4, p. 1334-1343 10 p.

Research output: Contribution to journalArticle

Phosphatidylethanolamine Binding Protein
raf Kinases
Glycogen Synthase Kinase 3
Protein Kinases
Proteins

The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Li, Y., McKenna, E. O., Parkes, W., Pitt, A. R. & Walton, A. J., 15 Aug 2011, In : Applied Physics Letters. 99, 7, 3 p., 073703.

Research output: Contribution to journalArticle

Open Access
File
aqueous solutions
proteins
fabrication
thin films
2010
Quantum Dots
Semiconductor quantum dots
Western Blotting
Fluorescent Dyes
Color

A solvent-free matrix application method for matrix-assisted laser desorption/ionization imaging of small molecules

Goodwin, R. J., Macintyre, L., Watson, D. G., Scullion, S. P. & Pitt, A., 15 Jun 2010, In : Rapid communications in mass spectrometry. 24, 11, p. 1682-1686 5 p.

Research output: Contribution to journalArticle

Ionization
Desorption
Imaging techniques
Molecules
Lasers

Comprehensive human urine standards for comparability and standardization in clinical proteome analysis

Mischak, H., Kolch, W., Aivaliotis, M., Bouyssié, D., Court, M., Dihazi, H., Dihazi, G. H., Franke, J., Garin, J., Gonzalez de Peredo, A., Iphöfer, A., Jänsch, L., Lacroix, C., Makridakis, M., Masselon, C., Metzger, J., Monsarrat, B., Mrug, M., Norling, M., Novak, J. & 11 others, Pich, A., Pitt, A., Bongcam-Rudloff, E., Siwy, J., Suzuki, H., Thongboonkerd, V., Wang, L-S., Zoidakis, J., Zürbig, P., Schanstra, J. P. & Vlahou, A., Apr 2010, In : Proteomics. 4, 4, p. 464-78 15 p.

Research output: Contribution to journalArticle

Proteome
Proteomics
Standardization
Urine
Biomarkers

Effect of phosphatidylcholine chlorohydrins on human erythrocytes

Robaszkiewicz, A., Greig, F. H., Pitt, A. R., Spickett, C. M., Bartosz, G. & Soszyński, M., Sep 2010, In : Chemistry and Physics of Lipids. 163, 7, p. 639-647 9 p.

Research output: Contribution to journalArticle

Chlorohydrins
Phosphatidylcholines
Erythrocytes
Liposomes
Lipids

Mass spectrometry imaging of pharmacological compounds in tissue sections

Goodwin, R. J. A. & Pitt, A. R., Feb 2010, In : Bioanalysis. 2, 2, p. 279-293 15 p.

Research output: Contribution to journalArticle

Mass spectrometry
Mass Spectrometry
Pharmacology
Tissue
Imaging techniques

On-chip immunoprecipitation for protein purification

Sandison, M. E., Cumming, S. A., Kolch, W. & Pitt, A. R., 17 Aug 2010, In : Lab on a Chip. 2010, 20, p. 2805-2813 9 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Immunoprecipitation
Purification
Proteins
Antibodies

Stopping the clock on proteomic degradation by heat treatment at the point of tissue excision

Goodwin, R. J. A., Lang, A. M., Allingham, H., Borén, M. & Pitt, A. R., 9 May 2010, In : Proteomics. 10, 9, p. 1751-1761 11 p.

Research output: Contribution to journalArticle

Proteomics
Clocks
Hot Temperature
Heat treatment
Tissue

The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier

Sturm, O. E., Orton, R., Grindlay, J., Birtwistle, M., Vyshemirsky, V., Gilbert, D., Calder, M., Pitt, A., Kholodenko, B. & Kolch, W., 21 Dec 2010, In : Science Signaling. 3, 153, p. ra90

Research output: Contribution to journalArticle

Open Access
Feedback amplifiers
MAP Kinase Signaling System
Feedback
Phosphotransferases
Extracellular Signal-Regulated MAP Kinases

The Renilla luciferase gene as a reference gene for normalization of gene expression in transiently transfected cells

Jiwaji, M., Daly, R., Pansare, K., McLean, P., Yang, J., Kolch, W. & Pitt, A., 31 Dec 2010, In : BMC Molecular Biology. 11, p. 103

Research output: Contribution to journalArticle

Open Access
File
Renilla Luciferases
Gene Expression
Genes
Real-Time Polymerase Chain Reaction
Plasmids
Ionization
Rats
Desorption
Brain
Tissue
2009

Development of novel mass spectrometric methods for identifying HOCl-induced modifications to proteins

Mouls, L., Silajdzic, E., Haroune, N., Spickett, C. M. & Pitt, A. R., 1 Mar 2009, In : Proteomics. 9, 6, p. 1617-1631 15 p.

Research output: Contribution to journalArticle

Ions
Pulse time modulation
Proteins
5-Hydroxytryptophan
Scanning

Performance of five different electrospray ionisation sources in conjunction with rapid monolithic column liquid chromatography and fast MS/MS scanning

Burgess, K. E. V., Lainson, A., Imrie, L., Fraser-Pitt, D., Yaga, R., Smith, D. G. E., Swart, R., Pitt, A. R. & Inglis, N. F., Mar 2009, In : Proteomics. 9, 6, p. 1720-1726 7 p.

Research output: Contribution to journalArticle

Electrospray ionization
Column chromatography
Liquid chromatography
Ion sources
Liquid Chromatography

The C-terminus of Raf-1 acts as a 14-3-3-dependent activation switch

Dhillon, A. S., Yip, Y. Y., Grindlay, G. J., Pakay, J. L., Dangers, M., Hillmann, M., Clark, W., Pitt, A., Mischak, H. & Kolch, W., Nov 2009, In : Cellular Signalling. 21, 11, p. 1645-1651 7 p.

Research output: Contribution to journalArticle

14-3-3 Proteins
Phosphorylation
Mitogen-Activated Protein Kinase Kinases
Adenosine Triphosphate
Proto-Oncogene Proteins c-raf
2008

Characterisation of the plasma membrane subproteome of bloodstream form Trypanosoma brucei

Bridges, D. J., Pitt, A. R., Hanrahan, O., Brennan, K., Voorheis, H. P., Herzyk, P., de Koning, H. P. & Burchmore, R. J. S., Jan 2008, In : Proteomics. 8, 1, p. 83-99 17 p.

Research output: Contribution to journalArticle

Trypanosoma brucei brucei
Cell membranes
Proteome
Cell Membrane
Membrane Proteins
Hypochlorous Acid
Free Radicals
Phospholipids
Lipids
Chlorohydrins