Research output per year
Research output per year
Personal profile
Research Interests
Dr Kardeby is a cell signalling scientist with years of experience in drug target identification. Her research is in the field of Thrombosis in Inflammation with a focus on the effect of platelet and endothelial cell activation on vascular remodellling and neurodegeneration. In her work she uses novel pharmacological tools for understanding signalling mechanisms of cardiovascular disease.
Scholarship and Fellowship
Dr Kardeby is a Marie Curie Alumni, she held a Marie Skłodowska-Curie Actions Individual Fellowship funded by Horizon 2020 between 2020 and 2022 (#893262).
Clinical Experience
Dr Kardeby is a registered clinical Biomedical Scientist with the Swedish National Board of Health and Welfare. She has experience from working in clinical chemistry, histolgy and pathology, fertility laboratory, and a general practician surgery.
Education/Academic qualification
PhD, Medicine, specialisation Biomedicine
18 Nov 2014 → 29 May 2019
Award Date: 2 Jul 2019
MSc, Medicine, Örebro University
2011 → 2013
BSc, Biomedical laboratory science, Uppsala University
2008 → 2011
BSc, Medicine, Uppsala University
2008 → 2011
Keywords
- QP Physiology
- Thrombosis
- Platelets
- Endothelial cells
- Haemostasis
- Inflammation
- Glycosaminoglycans
- Neurodegeneration
- R Medicine (General)
- Parkinson's disease
- Aortic Aneurysms
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Heparin and heparin proteoglycan-mimetics activate platelets via PEAR1 and PI3Kβ
Kardeby, C., Evans, A., Campos, J., Al-Wahaibi, A. M., Smith, C. W., Slater, A., Martin, E. M., Severin, S., Brill, A., Pejler, G., Sun, Y. & Watson, S. P., 1 Jan 2023, In: Journal of Thrombosis and Haemostasis. 21, 1, p. 101-116 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Is the endogenous ligand for PEAR1 a proteoglycan: clues from the sea
Kardeby, C., Damaskinaki, F-N., Sun, Y. & Watson, S. P., 18 Aug 2021, In: Platelets. 32, 6, p. 779-785 7 p.Research output: Contribution to journal › Letter, comment/opinion or interview › peer-review
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Synthetic glycopolymers and natural fucoidans cause human platelet aggregation via PEAR1 and GPIbα
Kardeby, C., Fälker, K., Haining, E. J., Criel, M., Lindkvist, M., Barroso, R., Påhlsson, P., Ljungberg, L. U., Tengdelius, M., Rainger, G. E., Watson, S., Eble, J. A., Hoylaerts, M. F., Emsley, J., Konradsson, P., Watson, S. P., Sun, Y. & Grenegård, M., 12 Feb 2019, (E-pub ahead of print) In: Blood advances. 3, 3, p. 275-287 12 p.Research output: Contribution to journal › Article › peer-review
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Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2 and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand
Martin, E. M., Clark, J. C., Montague, S. J., Moran, L. A., Di, Y., Bull, L. J., Whittle, L., Raka, F., Buka, R. J., Zafar, I., Kardeby, C., Slater, A. & Watson, S. P., Jan 2024, In: Journal of Thrombosis and Haemostasis. 22, 1, p. 271-285 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Novel purine analogues regulate IL-1β release via inhibition of JAK activity in human aortic smooth muscle cells
Paramel, G. V., Lindkvist, M., Idosa, B. A., Sebina, L. S., Kardeby, C., Fotopoulou, T., Pournara, D., Kritsi, E., Ifanti, E., Zervou, M., Koufaki, M., Grenegård, M. & Fransén, K., 15 Aug 2022, In: European Journal of Pharmacology. 929, 10 p., 175128.Research output: Contribution to journal › Article › peer-review
Open AccessFile
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European Platelet Network Meeting
Caroline Kardeby (Chair)
4 Sept 2023 → 6 Sept 2023Activity: Participating in or organising an event types › Participation in conference
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Cells (Journal)
Caroline Kardeby (Peer reviewer)
2023 → …Activity: Peer-review and editorial work types › Publication peer-review
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International Society on Thrombosis And Haemostasis Congress
Caroline Kardeby (Participant)
9 Jul 2022 → 13 Jul 2022Activity: Participating in or organising an event types › Participation in conference
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Frontiers in Cardiovascular Medicine (Journal)
Caroline Kardeby (Peer reviewer)
2022 → …Activity: Peer-review and editorial work types › Publication peer-review
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Cancer Investigation (Journal)
Caroline Kardeby (Peer reviewer)
2021 → …Activity: Peer-review and editorial work types › Publication peer-review