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Personal profile

General

I joined the School of Life & Health Sciences in August 2016 as a Lecturer in Biosciences, after conducting postdoctoral research with Dame Prof. Linda Partridge (Institute of Healthy Ageing, University College London) and Prof. William Chia (MRC Centre for Developmental Neurobiology, Kings College London). My research background covers ageing biology, cell signalling and Drosophila genetics. 

Research Interests

My current research aims to understand the molecular and cellular mechanisms that govern how an animal ages using the fruit fly, Drosophila melanogaster, as a model system. Current key research topics of interest include:

  • Understanding the regulatory networks that control the activity of key proteins within the insulin signalling pathway.
  • Exploring the role of energy balance and metabolism in regulating lifespan.
  • Developing pharmacological interventions that extend lifespan and improve life-long health.

Qualifications

PhD Genetics, Imperial College London, 2002.

BSc(Hons) Biological Sciences, University of Southampton, 1998.

Employment

  • 2016 – date: Lecturer in Biosciences, School of Life & Health Sciences, Aston University.
  • 2005 – 2016: Senior Postdoctoral Research Associate/Max Planck Research Fellow, Institute of Healthy Ageing, University College London.
  • 2002 – 2005: Postdoctoral Research Associate, MRC Centre for Developmental Neurobiology, Kings College London.

Membership of Professional Bodies

  • Fellow of the Higher Eduation Academy (FHEA).
  • Member of the Biochemical Society.
  • Member of the British Society for Research on Ageing (BSRA).

Teaching Activity

Undergraduate

  • BC1005 Genetics
  • BY2EN2 Endocrinology

Postgraduate

  • BI4014 Cellular Differentiation in Developmental Biology
  • BI4018 Ageing and Regenerative Medicine

Programme Director: MRes in Biosciences

Professional/editorial offices

  • Trustee for the British Society for Research on Ageing (BSRA).

Contact Details

Room: MB438U
Tel: +44 (0) 121 204 4017
Email: c.slack@aston.ac.uk

Fingerprint Dive into the research topics where Cathy Slack is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Drosophila Medicine & Life Sciences
Insulin Medicine & Life Sciences
Aging of materials Chemical Compounds
Diptera Medicine & Life Sciences
Drosophila melanogaster Medicine & Life Sciences
Caenorhabditis elegans Medicine & Life Sciences
insulin Agriculture & Biology
Chemical activation Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2006 2019

Signal Transduction Pathways in Ageing

Slack, C. & Tullet, J., 19 Feb 2019, Biochemistry and Cell Biology of Ageing: Part I Biomedical Science. Springer, Vol. 90. p. 323-350 28 p. (Sub-cellular biochemistry).

Research output: Chapter in Book/Report/Conference proceedingChapter

Signal transduction
Signal Transduction
Aging of materials
Cell signaling
Molecules

Ras signaling in aging and metabolic regulation

Slack, C., 7 Dec 2017, 4, 3, p. 195-205 11 p.

Research output: Contribution to journalReview article

Open Access
File
signal transduction
Signal Transduction
Signal transduction
Aging of materials
ras Proteins

Could cancer drugs provide ammunition against aging?

Slack, C., Alic, N. & Partridge, L., 17 Jan 2016, 15, 2, p. 153-155 3 p.

Research output: Contribution to journalEditorial

Lithium promotes longevity through GSK3/NRF2-dependent hormesis

Castillo-Quan, J. I., Li, L., Kinghorn, K. J., Ivanov, D. K., Tain, L. S., Slack, C., Kerr, F., Nespital, T., Thornton, J., Hardy, J., Bjedov, I. & Partridge, L., 19 Apr 2016, 15, 3, p. 638-650 13 p.

Research output: Contribution to journalArticle

Open Access
File
Hormesis
Lithium
Glycogen Synthase Kinase 3
NF-E2 Transcription Factor
Aging of materials

The Ras-Erk-ETS-signaling pathway is a drug target for longevity

Slack, C., Alic, N., Foley, A., Cabecinha, M., Hoddinott, M. P. & Partridge, L., 2 Jul 2015, In : Cell. 162, 1, p. 72-83 12 p.

Research output: Contribution to journalArticle

Open Access
File
Aging of materials
Pharmacology
Insulin-Like Growth Factor I
Pharmaceutical Preparations
Drosophila