If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
Article

Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in drosophila

Slack, C., Foley, A. & Partridge, L., 16 Oct 2012, In : PLoS ONE. 7, 10, 7 p., e47699.

Research output: Contribution to journalArticle

Open Access
File

A mosaic genetic screen for novel mutations affecting Drosophila neuroblast divisions

Slack, C., Somers, W. G., Sousa-Nunes, R., Chia, W. & Overton, P. M., 2006, In : Genetics. 7, 33.

Research output: Contribution to journalArticle

Open Access
File

Asymmetric localisation of Miranda and its cargo proteins during neuroblast division requires the anaphase-promoting complex/cyclosome

Slack, C., Overton, P. M., Tuxworth, R. I. & Chia, W., Nov 2007, In : Development. 134, 21, p. 3781-3787 7 p.

Research output: Contribution to journalArticle

Open Access
File

Cell-nonautonomous effects of dFOXO/DAF-16 in aging

Alic, N., Tullet, J. M., Niccoli, T., Broughton, S., Hoddinott, M. P., Slack, C., Gems, D. & Partridge, L., 27 Feb 2014, In : Cell Reports. 6, 4, p. 608-616 9 p.

Research output: Contribution to journalArticle

Open Access
File

Detrimental effects of RNAi: a cautionary note on its use in drosophila ageing studies

Alic, N., Hoddinott, M. P., Foley, A., Slack, C., Piper, M. D. W. & Partridge, L., 17 Sep 2012, In : PLoS ONE. 7, 9, 5 p., e45367.

Research output: Contribution to journalArticle

Open Access
File

dFOXO-independent effects of reduced insulin-like signaling in drosophila

Slack, C., Giannakou, M. E., Foley, A., Goss, M. & Partridge, L., Oct 2011, In : Aging Cell. 10, 5, p. 735-748 14 p.

Research output: Contribution to journalArticle

Open Access
File

DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition

Broughton, S. J., Slack, C., Alic, N., Metaxakis, A., Bass, T. M., Driege, Y. & Partridge, L., Jun 2010, In : Aging Cell. 9, 3, p. 336-346 11 p.

Research output: Contribution to journalArticle

Open Access

Expression and purification of recombinant G protein-coupled receptors: A review

Wiseman, D. N., Otchere, A., Patel, J. H., Uddin, R., Pollock, N. L., Routledge, S. J., Rothnie, A. J., Slack, C., Poyner, D. R., Bill, R. M. & Goddard, A. D., 1 Mar 2020, In : Protein Expression and Purification. 167, 105524.

Research output: Contribution to journalArticle

Open Access
File

Genes, pathways and metabolism in ageing

Slack, C. & Partridge, L., Jun 2013, In : Drug Discovery Today: Disease Models. 10, 2, p. e87–e93 13 p.

Research output: Contribution to journalArticle

Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling

Alic, N., Andrews, T. D., Giannakou, M. E., Papatheodorou, I., Slack, C., Hoddinott, M. P., Cochemé, H. M., Schuster, E. F., Thornton, J. M. & Partridge, L., 2011, In : Molecular Systems Biology. 7, 1, 17 p., 502.

Research output: Contribution to journalArticle

Open Access
File

Insulin signalling regulates remating in female drosophila

Wigby, S., Slack, C., Grönke, S., Martinez, P., Calboli, F. C. F., Chapman, T. & Partridge, L., 7 Feb 2011, In : Proceeding of the Royal Society: Series B. 278, 1704, p. 424-431 8 p.

Research output: Contribution to journalArticle

Open Access
File

Lithium promotes longevity through GSK3/NRF2-dependent hormesis

Castillo-Quan, J. I., Li, L., Kinghorn, K. J., Ivanov, D. K., Tain, L. S., Slack, C., Kerr, F., Nespital, T., Thornton, J., Hardy, J., Bjedov, I. & Partridge, L., 19 Apr 2016, In : Cell Reports. 15, 3, p. 638-650 13 p.

Research output: Contribution to journalArticle

Open Access
File

Mechanisms of life span extension by rapamycin in the fruit fly drosophila melanogaster

Bjedov, I., Toivonen, J. M., Kerr, F., Slack, C., Jacobson, J., Foley, A. & Partridge, L., 6 Jan 2010, In : Cell metabolism. 11, 1, p. 35-46 12 p.

Research output: Contribution to journalArticle

Open Access
File

Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs

Broughton, S., Alic, N., Slack, C., Bass, T., Ikeya, T., Vinti, G., Tommasi, A. M., Driege, Y., Hafen, E. & Partridge, L., 13 Nov 2008, In : PLoS ONE. 3, 11, e3721.

Research output: Contribution to journalArticle

Open Access
File

Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk

Slack, C., Werz, C., Wieser, D., Alic, N., Foley, A., Stocker, H., Withers, D. J., Thornton, J. M., Hafen, E. & Partridge, L., 19 Mar 2010, In : PLoS Genetics. 6, 3, 15 p., e1000881.

Research output: Contribution to journalArticle

Open Access
File

The Ras-Erk-ETS-signaling pathway is a drug target for longevity

Slack, C., Alic, N., Foley, A., Cabecinha, M., Hoddinott, M. P. & Partridge, L., 2 Jul 2015, In : Cell. 162, 1, p. 72-83 12 p.

Research output: Contribution to journalArticle

Open Access
File