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Personal profile

Research Interests

  • Behavioural Neuroscience
  • Learning and Memory
  • Memory Reconsolidation

Teaching Activity

  • Module coordinator for BY1HP1: Physiology for Biologists
  • Personal tutor
  • Final year project supervisor

General

I joined Aston as a Lecturer in Biosciences in January 2019, where I teach Physiology. Prior to this I was a Post-Doctoral Research Fellow in the Memory Persistence Lab at the University of Birmingham, where I investigated how memories are modified or updated via a process called memory reconsolidation. Understanding memory reconsolidation could be extremely important for the treatment of phobias, post-traumatic stress disorder (PTSD) and addiction. I love joining in with outreach events and getting to chat to people about how our brains work.

Education/Academic qualification

PhD, University of Bristol

1 Jan 20061 Jun 2009

Keywords

  • QP Physiology
  • Neuroscience
  • Memory
  • Reconsolidation
  • Behaviour
  • Learning
  • Neuronal pathways
  • Pharmacology

Fingerprint Dive into the research topics where Charlotte Law is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Fear Medicine & Life Sciences
Dizocilpine Maleate Medicine & Life Sciences
Long Noncoding RNA Medicine & Life Sciences
Brain-Derived Neurotrophic Factor Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Gene Expression Regulation Medicine & Life Sciences
Amygdala Medicine & Life Sciences
Cerebellum Medicine & Life Sciences

Research Output 2011 2019

Dopaminergic D1 receptor signalling is necessary, but not sufficient for cued fear memory destabilisation

Lee, J. & Flavell, C., 15 Jul 2019, (Accepted/In press) In : Psychopharmacology.

Research output: Contribution to journalArticle

Open Access
File
Fear
Mifepristone
Dopamine D1 Receptors
Pharmacology
Nootropic Agents

Postretrieval Relearning Strengthens Hippocampal Memories via Destabilization and Reconsolidation.

Rong Tay, K., Law, C., Cassini, L. F., Wimber, M. & Lee, J., 6 Feb 2019, In : Journal of Neuroscience. 39, 6, p. 1109-1118 10 p.

Research output: Contribution to journalArticle

Open Access
File
Paired-Associate Learning
Learning
Proteasome Endopeptidase Complex
Proteolysis
Fear

On the transition from reconsolidation to extinction of contextual fear memories.

Cassini, L. F., Law, C., Amaral, O. B. & Lee, J., 16 Aug 2017, 24, p. 392-399

Research output: Contribution to journalArticle

Open Access
File
Fear
Dizocilpine Maleate
Freezing
N-Methyl-D-Aspartate Receptors
Injections

Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated With Anxiety-like Behavior in Mice

Spadaro, P. A., Law, C. R., Widagdo, J., Ratnu, V. S., Troup, M., Ragan, C., Mattick, J. S. & Bredy, T. W., 15 Dec 2015, In : Biological Psychiatry. 78, 12, p. 848-859

Research output: Contribution to journalArticle

Open Access
File
Long Noncoding RNA
Gene Expression Regulation
Epigenomics
Anxiety
Prefrontal Cortex

Inhibition and enhancement of contextual fear memory destabilization.

Lee, J. & Law, C., 28 Apr 2014, 8, 144.

Research output: Contribution to journalArticle

Open Access
File
Fear
Sulfasalazine
Hippocampus
I-kappa B Kinase
Inhibition (Psychology)