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Research Output 1994 2019

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Meeting abstract
2018

Analysis of phospholipid peroxidation and protein lipoxidation products by LC-MS

Spickett, C. M., Sousa, B. C. & Pitt, A. R., 15 Aug 2018, In : Free Radical Biology and Medicine. 124, p. 560

Research output: Contribution to journalMeeting abstract

Phospholipids
Proteins
Bioactivity
Mass spectrometry
Apolipoprotein B-100

Detecting lipoxidation: diagnostic tools for the translation and commercial application

Campos-Pinto, I., Wilkins, J., Schouten, J., Davis, P. & Spickett, C. M., 15 Aug 2018, In : Free Radical Biology and Medicine. 124, p. 566

Research output: Contribution to journalMeeting abstract

Serum Albumin
Antibodies
Assays
Sheep
4-hydroxy-2-nonenal

Developing targeted mass spectrometry approaches for the identification of protein lipoxidation

Spickett, C. M., Bhurrut, E. J. B., Sousa, B. C., Afonso, C. B., Durand, T. & Pitt, A. R., 14 May 2018, In : Free Radical Biology and Medicine. 120, Suppl 1, p. S86-S87

Research output: Contribution to journalMeeting abstract

Effect of short-chain aldehydes on the enzymatic activity of pyruvate kinase

Sousa, B. C., Ashman, J., Spickett, C. M. & Pitt, A. R., 14 May 2018, In : Free Radical Biology and Medicine. 120, Suppl 1, p. S32

Research output: Contribution to journalMeeting abstract

Immunodetecting lipoxidation: epitope mapping of HNE-modified human serum albumin using two different anti-HNE pAbs

Campos-pinto, I., Wilkins, J., Schouten, J., Pitt, A., Spickett, C. & Davis, P., 20 May 2018, In : Free Radical Biology and Medicine. 120, Suppl 1, p. S50-S51

Research output: Contribution to journalMeeting abstract

YO-1 Synthesis and separation of peptide-oxidized phospholipid adducts, a potential lipoxidation marker

Afonso, C. B., Pitt, A. R. & Spickett, C. M., 14 May 2018, In : Free Radical Biology and Medicine. 120, Suppl 1, p. S27

Research output: Contribution to journalMeeting abstract

2015

Investigating the ability of antibodies to recognize specific oxidized protein epitopes

Meredith, S., Spickett, C., Parekh, G., Schouten, J., Griffiths, H. & Davis, P., Sep 2015, In : Free Radical Biology and Medicine. 86, Suppl.1, p. S31 1 p., PP36.

Research output: Contribution to journalMeeting abstract

Epitopes
Peptides
Antibodies
Proteins
Serum
Mass spectrometry
Mass Spectrometry
Phospholipids
divinyl benzene
Phosphatidylcholines

Uncovering changes in the redox protein interactome of PTEN

Spickett, C. M., Verrastro, I. & Pitt, A. R., Sep 2015, In : Free Radical Biology and Medicine. 86, Suppl.1, p. S9 1 p., OP15.

Research output: Contribution to journalMeeting abstract

Phosphoprotein Phosphatases
Phosphoric Monoester Hydrolases
Oxidation-Reduction
Tensins
Proteins
2014

Detection and quantification of protein oxidation in sarcopenic models: a mass spectrometry study

Pasha, S., Tveen Jensen, K., Pitt, A. R. & Spickett, C. M., Oct 2014, In : Free Radical Biology and Medicine. 75, Suppl.1, p. S44 1 p., P68.

Research output: Contribution to journalMeeting abstract

Tandem Mass Spectrometry
Mass spectrometry
Mass Spectrometry
Muscle
Oxidation

Mapping nitro-tyrosine modifications in fibrinogen by mass spectrometry as a biomarker for inflammatory disease

Meredith, S., Parekh, G., Towler, J., Schouten, J., Davis, P., Griffiths, H. & Spickett, C., Oct 2014, In : Free Radical Biology and Medicine. 75, Suppl.1, p. S50 1 p., P87.

Research output: Contribution to journalMeeting abstract

Biomarkers
Fibrinogen
Mass spectrometry
Tyrosine
Mass Spectrometry

Oxidised LDL lipids, statins and a blood-brain barrier

Griffiths, H., Dias, I., Lip, G. Y. H., Spickett, C. & Polidori, C., Oct 2014, In : Free Radical Biology and Medicine. 75, Suppl.1, p. S15-S16 2 p., OP2-3.

Research output: Contribution to journalMeeting abstract

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Blood-Brain Barrier
LDL Lipoproteins
Lipids
8-epi-prostaglandin F2alpha

Targeted mass spectrometry methods for detecting oxidative post-translational modifications

Tveen-Jensen, K., Reis, A., Spickett, C. M. & Pitt, A. R., 1 Oct 2014, In : Free Radical Biology and Medicine. 75, Suppl.1, p. S52-S53 2 p., P93.

Research output: Contribution to journalMeeting abstract

Post Translational Protein Processing
Apolipoprotein B-100
Mass spectrometry
Mass Spectrometry
Ions
2013

Protein modification and phospholipid oxidation

Spickett, C. M., Tveen-jensen, K., Reis, A. & Pitt, A. R., 20 Sep 2013, In : Free Radical Biology and Medicine. 65, Suppl.1, p. S15 1 p.

Research output: Contribution to journalMeeting abstract

Phospholipids
Ions
Apolipoprotein B-100
Oxidation
Proteins

Residue-specific investigation of the relationship between oxidation and activity of a dual specificity phosphatase by mass spectrometry

Calimport, S., Pitt, A. R. & Spickett, C. M., 5 Nov 2013, In : Free Radical Biology and Medicine. 65, Suppl.2, p. S57 1 p., PSS110.

Research output: Contribution to journalMeeting abstract

Dual-Specificity Phosphatases
Oxidation-Reduction
Mass spectrometry
Cysteine
Mass Spectrometry
2012

Effects of oxidized and chlorinated phospholipids on signaling pathways in endothelial cells

Fauzi, N. M., Torrance, E., Neamatallah, T., Ho, H. K., Spickett, C. M. & Plevin, R., May 2012, In : Vascular Pharmacology. 56, 5-6, p. 373 1 p., P.13.7.

Research output: Contribution to journalMeeting abstract

Phospholipids
Endothelial Cells
Lipids
Phosphorylcholine
Blood Vessels

Integrated Omics for the global mapping of biomolecules in LDL

Reis, A., Spickett, C. M. & Rudnitskaya, A., Sep 2012, In : Free Radical Biology and Medicine. 53, Supplement 1, p. S212 1 p., 0560.

Research output: Contribution to journalMeeting abstract

Biomolecules
LDL Lipoproteins
Apolipoprotein B-100
Pathology
Lipids

Mapping oxidative modifications of PTEN

Tveen Jensen, K., Calimport, S. R. G., Verrastro, I., Spickett, C. M. & Pitt, A. R., Sep 2012, In : Free Radical Biology and Medicine. 53, Supplement 1, p. S213 1 p., 0576.

Research output: Contribution to journalMeeting abstract

PTEN Phosphohydrolase
Proteins
Protein Interaction Domains and Motifs
Hypochlorous Acid
Chromosomes, Human, Pair 10

Mass spectrometry analysis of modified bee venom phospholipase A2 in correlation with increased activity

Pasha, S., Mahalka, A. K., Reis, A., Pitt, A. R., Kinnunen, P. K. J. & Spickett, C. M., 2 Sep 2012, In : Free Radical Biology and Medicine. 53, Supplement 1, p. S213-S214 2 p., 0578.

Research output: Contribution to journalMeeting abstract

Bee Venoms
Phospholipases A2
Mass spectrometry
Mass Spectrometry
Proteins

Mass spectrometry based strategies in the mapping of modified LDL

Reis, A. & Spickett, C. M., Sep 2012, In : Free Radical Biology and Medicine. 53, Supplement 1, p. S252 1 p., HNE.P.17 .

Research output: Contribution to journalMeeting abstract

Mass spectrometry
Mass Spectrometry
Apolipoprotein B-100
Proteins
Phospholipids

Proteomic and oxPTM analysis of neutrophil extracellular traps

Li, Y., Wright, H. J., Pitt, A. R., Chapple, I. L. C. & Spickett, C. M., Sep 2012, In : Free Radical Biology and Medicine. 53, Supplement 1, p. S170 1 p., 0583.

Research output: Contribution to journalMeeting abstract

Proteomics
Cell death
Proteins
Cell signaling
Serpins
2003

The biological effects of chlorohydrins and other products of HOCL attack: relevance to inflammation

Dever, G., Oliveira, C. P., Stewart, L. J. & Spickett, C. M., 2003, In : Free Radical Research. 37, p. 27 1 p.

Research output: Contribution to journalMeeting abstract

2002

Luminescent techniques for studying free radical production and cell viability in relation to cardiovascular disease and HRT

Lateef, S., Walker, J. J. & Spickett, C. M., 15 Jul 2002, In : Free Radical Biology and Medicine. 33, 2, Suppl.1, p. S28 1 p., 65.

Research output: Contribution to journalMeeting abstract

Luminescent Measurements
Hormone Replacement Therapy
Free Radicals
Cell Survival
Cardiovascular Diseases

Phagocyte oxidation of phospholipids: comparison of hydroperoxide, chlorohydrin and epoxyisoprostane formation by LC-MS

Spickett, C. M., Jerlich, A., Schaur, R. J. & Pitt, A. R., 15 Jul 2002, In : Free Radical Biology and Medicine. 33, 2, Suppl.1, p. S145 1 p., 379.

Research output: Contribution to journalMeeting abstract

Chlorohydrins
Phagocytes
Hydrogen Peroxide
Phospholipids
Lipids

The antioxidant potential of modified quercetins and quercetin-metal complexes

Spickett, C. M., Wojton, A., Kopacz, M. & Oleksyn, B., 15 Jul 2002, In : Free Radical Biology and Medicine. 33, 2, Suppl.1, p. S209-S210 2 p., 556.

Research output: Contribution to journalMeeting abstract

Coordination Complexes
Quercetin
Antioxidants
Polyphenols
Flavonoids
2000

A study into the effect of HRT on oxidative stress of erythrocytes

Homer, N. Z. M., Reglinski, J., Spickett, C. M., Wilson, R. & Walker, J. J., Dec 2000, In : Molecular Biology of the Cell. 11, Suppl, p. 402A-402A

Research output: Contribution to journalMeeting abstract