1994 …2020

Research output per year

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Research Output

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1994

Alteration of the erythrocyte glutathione redox balance by N-acetylcysteine, captopril and exogenous glutathione

Russell, J., Spickett, C. M., Reglinski, J., Smith, W. E., McMurray, J. & Abdullah, I. B., 27 Jun 1994, In : FEBS Letters. 347, 2-3, p. 215-220 6 p.

Research output: Contribution to journalArticle

The resolution of diterpene cyclase activities from Ricinus communis

Spickett, C. M., Ponnamperuma, K. & Abell, C., Nov 1994, In : Phytochemistry. 37, 4, p. 971-973 3 p.

Research output: Contribution to journalArticle

1998

Direct observation of lipid hydroperoxides in phospholipid vesicles by electrospray mass spectrometry

Spickett, C. M., Pitt, A. R. & Brown, A. J., Sep 1998, In : Free Radical Biology and Medicine. 25, 4-5, p. 613-620 8 p.

Research output: Contribution to journalArticle

Erythrocyte glutathione balance and membrane stability during preeclampsia

Spickett, C. M., Reglinski, J., Smith, W. E., Wilson, R., Walker, J. J. & McKillop, J., Apr 1998, In : Free Radical Biology and Medicine. 24, 6, p. 1049-1055 7 p.

Research output: Contribution to journalArticle

Oxidation of erythrocyte glutathione by monocytes stimulated with interleukin-6   : analysis by 1H spin echo NMR

Spickett, C. M., Smith, W. E., Reglinski, J., Wilson, R. & Walker, J. J., 23 Feb 1998, In : Clinica Chimica Acta. 270, 2, p. 115-124 10 p.

Research output: Contribution to journalArticle

1999

H-1 nmr as a non-invasive probe of amniotic fluid in insulin dependant diabetes mellitus

McGowan, P. E., Lawrie, W. C., Reglinski, J., Spickett, C. M., Wilson, R., Walker, J. J., Wisdom, S. & MacLean, M. A., 1999, In : Journal of Perinatal Medicine. 27, 5, p. 404-408 5 p.

Research output: Contribution to journalArticle

2000

Pathways of phospholipid oxidation by HOCL in human LDL detected by LC-MS

Jerlich, A., Pitt, A. R., Schaur, R. J. & Spickett, C. M., 1 Mar 2000, In : Free Radical Biology and Medicine. 28, 5, p. 673-682 10 p.

Research output: Contribution to journalArticle

The reactions of hypochlorous acid, the reactive oxygen species produced by myeloperoxidase, with lipids

Spickett, C. M., Jerlich, A., Panasenko, O. M., Arnhold, J., Pitt, A. R., Stelmaszynska, T. & Schaur, R. J., 2000, In : Acta Biochimica Polonica. 47, 4, p. 889-899 11 p.

Research output: Contribution to journalArticle

2001

Detection of phospholipid oxidation in oxidatively stressed cells by reversed-phase HPLC coupled with positive-ionization electrospray MS

Spickett, C. M., Rennie, N., Winter, H., Zambonin, L., Landi, L., Jerlich, A., Schaur, R. J. & Pitt, A. R., 15 Apr 2001, In : Biochemical Journal. 355, 2, p. 449-457 9 p.

Research output: Contribution to journalArticle

2003

Phospholipid chlorohydrins cause ATP depletion and toxicity in human myeloid cells

Dever, G., Stewart, L-J., Pitt, A. & Spickett, C. M., 10 Apr 2003, In : FEBS Letters. 540, 1-3, p. 245-250 6 p.

Research output: Contribution to journalArticle

Open Access
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The formation of phosphatidylcholine oxidation products by stimulated phagocytes

Jerlich, A., Schaur, R. J., Pitt, A. R. & Spickett, C. M., Jun 2003, In : Free Radical Research. 37, 6, p. 645-653 9 p.

Research output: Contribution to journalArticle

The interaction of sodium chlorite with phospholipids and glutathione: a comparison of effects in vitro, in mammalian and in microbial cells

Ingram, P. R., Homer, N. Z. M., Smith, R. A., Pitt, A. R., Wilson, C. G., Olejnik, O. & Spickett, C. M., 1 Feb 2003, In : Archives of Biochemistry and Biophysics. 410, 1, p. 121-133 13 p.

Research output: Contribution to journalArticle

The in vivo susceptibility of Leishmania donovani to sodium stibogluconate is drug specific and can be reversed by inhibiting glutathione biosynthesis

Carter, K. C., Sundar, S., Spickett, C., Pereira, O. C. & Mullen, A. B., May 2003, In : Antimicrobial Agents and Chemotherapy. 47, 5, p. 1529-1535 7 p.

Research output: Contribution to journalArticle

Open Access
File
2004

A comparison of the effects of ocular preservatives on mammalian and microbial ATP and glutathione levels

Ingram, P. R., Pitt, A. R., Wilson, C. G., Olejnik, O. & Spickett, C. M., Jul 2004, In : Free Radical Research. 38, 7, p. 739-750 12 p.

Research output: Contribution to journalArticle

Fatty acid composition, antioxidants and lipid oxidation in chicken breasts from different production regimes

Jahan, K., Paterson, A. & Spickett, C. M., Apr 2004, In : International Journal of Food Science and Technology. 39, 4, p. 443-453 11 p.

Research output: Contribution to journalArticle

2005

Chemometric modelling to relate antioxidants, neutral lipid fatty acids and flavour components in chicken breast

Jahan, K., Paterson, A., Piggott, J. & Spickett, C., 2005, In : Poultry Science. 84, 1, p. 158-166 9 p.

Research output: Contribution to journalArticle

Dimethylsulfoxide oxidizes glutathione in vitro and in human erythrocytes: kinetic analysis by 1H NMR

Homer, N. Z. M., Reglinski, J., Sowden, R., Spickett, C. M., Wilson, R. & Walker, J. J., Jun 2005, In : Cryobiology. 50, 3, p. 317-324 8 p.

Research output: Contribution to journalArticle

Studies of phospholipid oxidation by electrospray mass spectrometry: from analysis in cells to biological effects

Spickett, C. M. & Dever, G., Dec 2005, In : Biofactors. 24, 1-4, p. 17-31 15 p.

Research output: Contribution to journalArticle

Studies of potential atherogenic properties of phospholipid chlorohydrins

Spickett, C. M., Dever, G., Kennedy, S. & Wainwright, C. L., Mar 2005, In : Free Radical Research. 39, Suppl.1, p. S79 1 p.

Research output: Contribution to journalArticle

2006

Fatty acid and phospholipid chlorohydrins cause cell stress and endothelial adhesion

Dever, G., Wainwright, C. L., Kennedy, S. & Spickett, C. M., 2006, In : Acta Biochimica Polonica. 53, 4, p. 761-768 8 p.

Research output: Contribution to journalArticle

Proteomic analysis of phosphorylation, oxidation and nitrosylation in signal transduction

Spickett, C. M., Pitt, A. R., Morrice, N. & Kolch, W., Dec 2006, In : BBA - Proteins and Proteomics. 1764, 12, p. 1823-1841 19 p.

Research output: Contribution to journalArticle

2007

A high-fat meal induces low-grade endotoxemia: evidence of a novel mechanism of postprandial inflammation

Erridge, C., Attina, T., Spickett, C. M. & Webb, D. J., Nov 2007, In : American Journal of Clinical Nutrition. 86, 5, p. 1286-1292 7 p.

Research output: Contribution to journalArticle

Chlorinated lipids and fatty acids: an emerging role in pathology

Spickett, C. M., Sep 2007, In : Pharmacology and Therapeutics. 115, 3, p. 400-409 10 p.

Research output: Contribution to journalArticle

Non-enterobacterial endotoxins stimulate human coronary artery but not venous endothelial cell activation via toll-like receptor 2

Erridge, C., Spickett, C. M. & Webb, D. J., 1 Jan 2007, In : Cardiovascular Research. 73, 1, p. 181-189 9 p.

Research output: Contribution to journalArticle

Oxidised phospholipid regulation of toll-like receptor signalling

Erridge, C. & Spickett, C. M., 1 Feb 2007, In : Redox report. 12, 1-2, p. 76-80 5 p.

Research output: Contribution to journalArticle

Open Access
File

Toll-like receptor 4 signalling is neither sufficient nor required for oxidised phospholipids mediated induction of interleukin-8 expression

Erridge, C., Webb, D. J. & Spickett, C. M., Jul 2007, In : Atherosclerosis. 193, 1, p. 77-85 9 p.

Research output: Contribution to journalArticle

2008

Copper N2S2 Schiff base macrocycles: the effect of structure on redox potential

Taylor, M. K., Trotter, K. D., Reglinski, J., Berlouis, L. E. A., Kennedy, A. R., Spickett, C. M. & Sowden, R. J., 27 Jun 2008, In : Inorganica Chimica Acta. 361, 9-10, p. 2851-2862 12 p.

Research output: Contribution to journalArticle

Open Access
File

Phospholipid chlorohydrin induces leukocyte adhesion to Apoe(-/-) mouse arteries via upregulation of P-selectin

Dever, G., Benson, R., Wainwright, C. L., Kennedy, S. & Spickett, C. M., 1 Feb 2008, In : Free Radical Biology and Medicine. 44, 3, p. 452-463 12 p.

Research output: Contribution to journalArticle

Vascular cell responsiveness to toll-like receptor ligands in carotid atheroma

Erridge, C., Burdess, A., Jackson, A. J., Murray, C., Riggio, M., Lappin, D., Milligan, S., Spickett, C. M. & Webb, D. J., Oct 2008, In : European journal of clinical investigation. 38, 10, p. 713-720 8 p.

Research output: Contribution to journalArticle

2009

Development of novel mass spectrometric methods for identifying HOCl-induced modifications to proteins

Mouls, L., Silajdzic, E., Haroune, N., Spickett, C. M. & Pitt, A. R., 1 Mar 2009, In : Proteomics. 9, 6, p. 1617-1631 15 p.

Research output: Contribution to journalArticle

Modulation of SERCA in the chronic phase of adjuvant arthritis as a possible adaptation mechanism of redox imbalance

Strosova, M., Karlovska, J., Spickett, C. M., Orszagova, Z., Ponist, S., Bauerova, K., Mihalova, D. & Horakova, L., Sep 2009, In : Free Radical Research. 43, 9, p. 852-864 13 p.

Research output: Contribution to journalArticle

Oxidative injury induced by hypochlorous acid to Ca-ATPase from sarcoplasmic reticulum of skeletal muscle and protective effect of trolox

Strosova, M., Karlovska, J., Spickett, C. M., Grune, T., Orszagova, Z. & Horakova, Z., Jun 2009, In : General Physiology and Biophysics. 28, 2, p. 195-209 15 p.

Research output: Contribution to journalArticle

Structural studies of trans-N2S2 copper macrocycles

Trotter, K. D., Reglinski, J., Robertson, K., Forgie, J. C., Parkinson, J. A., Kennedy, A. R., Armstrong, D. R., Sowden, R. J. & Spickett, C. M., 15 Aug 2009, In : Inorganica Chimica Acta. 362, 11, p. 4065-4072 8 p.

Research output: Contribution to journalArticle

2010

Advances in methods for the determination of biologically relevant lipid peroxidation products

Spickett, C. M., Wiswedel, I., Siems, W., Zarkovic, K. & Zarkovic, N., Oct 2010, In : Free Radical Research. 44, 10, p. 1172-1202 31 p.

Research output: Contribution to journalArticle

An inter-laboratory validation of methods of lipid peroxidation measurement in UVA-treated human plasma samples

Breusing, N., Grune, T., Andrisic, L., Atalay, M., Bartosz, G., Biasi, F., Borovic, S., Bravo, L., Casals, I., Casillas, R., Dinischiotu, A., Drzewinska, J., Faber, H., Fauzi, N. M., Gajewska, A., Gambini, J., Gradinaru, D., Kokkola, T., Lojek, A., Łuczaj, W. & 16 others, Margina, D., Mascia, C., Mateos, R., Meinitzer, A., Mitjavila, M. T., Mrakovcic, L., Munteanu, M. C., Podborska, M., Poli, G., Sicinska, P., Skrzydlewska, E., Vina, J., Wiswedel, I., Zarkovic, N., Zelzer, S. & Spickett, C. M., Oct 2010, In : Free Radical Research. 44, 10, p. 1203-1215 13 p.

Research output: Contribution to journalArticle

Open Access

Effect of phosphatidylcholine chlorohydrins on human erythrocytes

Robaszkiewicz, A., Greig, F. H., Pitt, A. R., Spickett, C. M., Bartosz, G. & Soszyński, M., Sep 2010, In : Chemistry and Physics of Lipids. 163, 7, p. 639-647 9 p.

Research output: Contribution to journalArticle

The structural and electrochemical consequences of hydrogenating Copper N2S2 Schiff base macrocycles

Trotter, K. D., Taylor, M. K., Forgie, J. C., Reglinski, J., Berlouis, L. E. A., Kennedy, A. R., Spickett, C. M. & Sowden, R. J., 20 Apr 2010, In : Inorganica Chimica Acta. 363, 7, p. 1529-1538 10 p.

Research output: Contribution to journalArticle

2011

Analysis of oxidized and chlorinated lipids by mass spectrometry and relevance to signalling

Spickett, C. M. & Fauzi, N. M., Oct 2011, In : Biochemical Society Transactions. 39, 5, p. 1233-1239 7 p.

Research output: Contribution to journalArticle

Analysis of radicals and radical reaction products in cell signalling and biomolecular damage: the long hard road to gold-standard measures

Winyard, P. G., Spickett, C. M. & Griffiths, H. R., Oct 2011, In : Biochemical Society Transactions. 39, 5, p. 1217-1220 4 p.

Research output: Contribution to journalArticle

Modulation of sarcoplasmic/endoplasmic reticulum Ca(2+)-ATPase activity and oxidative modification during the development of adjuvant arthritis

Strosova, M. K., Karlovska, J., Zizkova, P., Kwolek-Mirek, M., Ponist, S., Spickett, C. M. & Horakova, L., Jul 2011, In : Archives of Biochemistry and Biophysics. 511, 1-2, p. 40-47 8 p.

Research output: Contribution to journalArticle

Sensitivity of antioxidant-deficient yeast to hypochlorite and chlorite

Kwolek-Mirek, M., Bartosz, G. & Spickett, C. M., Aug 2011, In : Yeast. 28, 8, p. 595-609 15 p.

Research output: Contribution to journalArticle

2012

Chemistry of phospholipid oxidation

Reis Pereira, A. & Spickett, C. M., Oct 2012, In : BBA -Biomembranes. 1818, 10, p. 2374–2387 14 p.

Research output: Contribution to journalArticle

Physiological effects of oxidized phospholipids and their cellular signaling mechanisms in inflammation

Greig, F. H., Kennedy, S. & Spickett, C. M., 15 Jan 2012, In : Free Radical Biology and Medicine. 52, 2, p. 266-280 15 p.

Research output: Contribution to journalArticle