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Research Output

2020
Open Access
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2019

Retinal and peripheral vascular function in healthy individuals with low cardiovascular risk

Karimzad, S. E., Shokr, H. & Gherghel, D., 1 Nov 2019, In : Microvascular Research. 126, 103908.

Research output: Contribution to journalArticle

Open Access
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2018

Partially Lazy Classification of Cardiovascular Risk via Multi-way Graph Cut Optimization

Fathalla, K. M., Ekárt, A. & Gherghel, D., 28 Aug 2018, In : Procedia Computer Science. 126, p. 576-585 10 p.

Research output: Contribution to journalConference article

Open Access
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Retinal vascular function in asymptomatic individuals with a positive family history of cardiovascular disease

Seshadri, S., Karimzad, S., Shokr, H. & Gherghel, D., 1 Dec 2018, In : Acta Ophthalmologica. 96, 8, p. e956-e962

Research output: Contribution to journalArticle

Open Access
File
2017

Cardiovascular risk prediction based on retinal vessel analysis using machine learning

Fathalla, K., Ekárt, A., Seshadri, S. & Gherghel, D., 6 Feb 2017, 2016 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2016 - Conference Proceedings. IEEE, p. 880-885 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference publication

2016

Ageing effect on flicker-induced diameter changes in retinal microvessels of healthy individuals

Seshadri, S., Ekart, A. & Gherghel, D., Feb 2016, In : Acta Ophthalmologica. 94, 1, p. e35-e42

Research output: Contribution to journalArticle

Open Access
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Overweight status is associated with extensive signs of microvascular dysfunction and cardiovascular risk

Patel, S. R., Bellary, S., Karimzad, S. & Gherghel, D., 31 Aug 2016, In : Scientific Reports. 6, 8 p., 32282.

Research output: Contribution to journalArticle

Open Access
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2015

Retinal microvascular dysfunction occurs similarly in Alzheimer's disease and primary open angle glaucoma patients

Mroczkowska, S., Benavente-Pérez, A., Patel, S. R., Negi, A., Sung, V., Bentham, P. & Gherghel, D., 30 Jun 2015, In : Investigative Ophthalmology and Visual Science. 56, 7, p. 2763 1 p.

Research output: Contribution to journalConference abstract

Open Access

Systemic circulatory influences on retinal microvascular function in middle-age individuals with low to moderate cardiovascular risk

Seshadri, S., Mroczkowska, S., Qin, L., Patel, S., Ekárt, A. & Gherghel, D., Jun 2015, In : Acta Ophthalmologica. 93, 4, p. e266-e274 9 p.

Research output: Contribution to journalArticle

Open Access
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2014

Patients with early age-related macular degeneration exhibit signs of macro- and micro-vascular disease and abnormal blood glutathione levels

Qin, L., Mroczkowska, S. A., Ekart, A., Patel, S. R., Gibson, J. M. & Gherghel, D., 31 Jan 2014, In : Graefe's Archive for Clinical and Experimental Ophthalmology. 252, 1, p. 23-30 8 p.

Research output: Contribution to journalArticle

Retinal vascular dysfunction relates to cognitive impairment in Alzheimer's disease

Mroczkowska, S., Benavente-Pérez, A., Patel, S., Qin, L., Bentham, P. & Gherghel, D., 31 Oct 2014, In : Alzheimer Disease and Associated Disorders. 28, 4, p. 366-367 2 p.

Research output: Contribution to journalArticle

2013

Primary open-angle glaucoma vs normal-tension glaucoma: the vascular perspective

Mroczkowska, S., Benavente-Pérez, A., Negi, A., Sung, V., Patel, S. R. & Gherghel, D., Jan 2013, In : JAMA Ophthalmology. 131, 1, p. 36-43 8 p.

Research output: Contribution to journalArticle

2012

Abnormal retinal vascular reactivity in individuals with impaired glucose tolerance: a preliminary study

Patel, S. R., Bellary, S., Qin, L., Balanos, G. M., McIntyre, D. & Gherghel, D., Aug 2012, In : Investigative Ophthalmology and Visual Science. 53, 9, p. 5102-5108 7 p., IOVS-12-9512.

Research output: Contribution to journalArticle

Open Access
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Coexistence of macro- and micro-vascular abnormalities in newly diagnosed normal tension glaucoma patients

Mroczkowska, S., Ekárt, A., Sung, V., Negi, A., Qin, L., Patel, S., Jacob, S., Atkins, C., Benavente-Pérez, A. & Gherghel, D., Nov 2012, In : Acta Ophthalmologica Scandinavica. 90, 7, p. e553-e559 7 p., Acta-12-01-0065.

Research output: Contribution to journalArticle

2011

Abnormal retinal vascular function and lipid levels in a sample of healthy UK South Asians

Patel, S., Bellary, S., Qin, L., Gill, P. S., Taheri, S., Heitmar, R., Gibson, J. M. & Gherghel, D., 1 Mar 2011, In : British Journal of Ophthalmology. 95, 11, p. 1573-1576 4 p.

Research output: Contribution to journalArticle

Altered blood vessel responses in the eye and finger in coronary artery disease

Heitmar, R., Cubbidge, R. P., Lip, G. Y. H., Gherghel, D. & Blann, A. D., 3 Aug 2011, In : Investigative Ophthalmology and Visual Science. 52, 9, p. 6199-6205 7 p.

Research output: Contribution to journalArticle

Open Access
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Open Access
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Macular pigment optical density is related to blood glutathione levels in healthy individuals

Qin, L., Bartlett, H. E., Griffiths, H. R., Eperjesi, F., Armstrong, R. A. & Gherghel, D., 23 Aug 2011, In : Investigative Ophthalmology and Visual Science. 52, 9, p. 5029-5033 5 p.

Research output: Contribution to journalArticle

Open Access
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2010

Continuous retinal vessel diameter m easurements: the future in retinal vessel assessment?

Heitmar, R., Blann, A. D., Cubbidge, R. P., Lip, G. Y. H. & Gherghel, D., 30 Apr 2010, In : Investigative Ophthalmology and Visual Science. 51, 11, p. 5833-5839 7 p.

Research output: Contribution to journalArticle

Open Access
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Transient cardiac ischaemia and abnormal variations in systemic blood pressure in unselected primary open angle glaucoma patients

Gherghel, D., Hosking, S. L., Cunliffe, I. A. & Heitmar, R., Mar 2010, In : Ophthalmic and Physiological Optics. 30, 2, p. 175-81 7 p.

Research output: Contribution to journalArticle

Use of the retinal vessel analyzer in ocular blood flow research

Garhofer, G., Bek, T., Boehm, A. G., Gherghel, D., Grunwald, J., Jeppesen, P., Kergoat, H., Kotliar, K., Lanzl, I., Lovasik, J. V., Nagel, E., Vilser, W., Orgül, S. & Schmetterer, L., Nov 2010, In : Acta Ophthalmologica. 88, 7, p. 717-722 6 p.

Research output: Contribution to journalArticle

2009

A novel chronotherapeutic system for the treatment of primary open-angle glaucoma

Gherghel, D. & Conway, B., 18 Jun 2009, Patent No. P715802EP/1196/ US 2009/0155338 A1

Research output: Patent

Open Access

Ocular and systemic endothelial function in the off spring of diabetics: a pilot study

Patel, S., Gherghel, D., Heitmar, R., Benavente-Perez, A., Qin, L., McIntyre, D., Balanos, G. M. & Gibson, J., Sep 2009.

Research output: Contribution to conferenceAbstract

2008

First-line therapy with latanoprost 0.005% results in improved ocular circulation in newly diagnosed primary open-angle glaucoma patients: a prospective, 6-month, open-label study

Gherghel, D., Hosking, S. L., Cunliffe, I. A. & Armstrong, R. A., Mar 2008, In : Eye. 22, 3, p. 363-369 7 p.

Research output: Contribution to journalArticle

The effect of voluntary fasting and dehydration on flicker-induced retinal vascular dilation in a healthy individual: a case report

Heitmar, R., Gherghel, D., Armstrong, R. A., Cubbidge, R. P. & Hosking, S., 13 May 2008, In : Journal of Medical Case Reports. 2, 153, p. 1-7 7 p., 153.

Research output: Contribution to journalArticle

Open Access
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2007

Autonomic dysfunction in unselected and untreated primary open angle glaucoma patients: A pilot study

Gherghel, D., Hosking, S. L., Armstrong, R. A. & Cunliffe, I. A., Jul 2007, In : Ophthalmic and Physiological Optics. 27, 4, p. 336-341 6 p.

Research output: Contribution to journalArticle

2005

Beneficial effects of small-incision cataract surgery in patients demonstrating reduced ocular blood flow characteristics

Hilton, E. J. R., Hosking, S. L., Gherghel, D., Embleton, S. & Cunliffe, I. A., 2005, In : Eye. 19, 6, p. 670-675 6 p.

Research output: Contribution to journalArticle

Systemic reduction in glutathione levels occurs in patients with primary open-angle glaucoma

Gherghel, D., Griffiths, H. R., Hilton, E. J., Cunliffe, I. A. & Hosking, S. L., Mar 2005, In : Investigative Ophthalmology and Visual Science. 46, 3, p. 877-883 7 p.

Research output: Contribution to journalArticle

Open Access
File
2004
Open Access
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Autonomic nervous system, circadian rhythms, and primary open-angle glaucoma

Gherghel, D., Hosking, S. L. & Orgül, S., Sep 2004, In : Survey of ophthalmology. 49, 5, p. 491-508 18 p.

Research output: Contribution to journalArticle

Corneal pachymetry in normal and keratoconic eyes: Orbscan II versus ultrasound

Gherghel, D., Hosking, S. L., Mantry, S., Banerjee, S., Naroo, S. A. & Shah, S., Jun 2004, In : Journal of Cataract and Refractive Surgery. 30, 6, p. 1272-1277 6 p.

Research output: Contribution to journalArticle

2003

Contrast sensitivity improves after brimonidine therapy in primary open angle glaucoma: a case for neuroprotection

Evans, D. W., Hosking, S. L., Gherghel, D. & Bartlett, J. D., Dec 2003, In : British Journal of Ophthalmology. 87, 12, p. 1463-1465 3 p.

Research output: Contribution to journalArticle

Nidek OPD-scan analysis of normal, keratoconic, and penetrating keratoplasty eyes

Shah, S., Naroo, S., Hosking, S., Gherghel, D., Mantry, S., Bannerjee, S., Pedwell, K. & Bains, H. S., Mar 2003, In : Journal of Refractive Surgery . 19, 2, March Suppl. , p. S255-S259 5 p.

Research output: Contribution to journalArticle

2000

Relationship between ocular perfusion pressure and retrobulbar blood flow in patients with glaucoma with progressive damage

Gherghel, D., Orgul, S., Gugleta, K., Gekkieva, M. & Flammer, J., Nov 2000, In : American Journal of Ophthalmology. 130, 5, p. 597-605 9 p.

Research output: Contribution to journalLetter