Photo of Eric Hill
  • Phone0121 204 5040
  • School of Life & Health Sciences, Aston Triangle

    B4 7ET Birmingham

    United Kingdom

20072019
If you made any changes in Pure these will be visible here soon.

Personal profile

Research Interests

My main research interests include the development of tissue engineering strategies to model stem cell behaviour in the development of neuronal networks and also during neurodegeneration.  I am currently engaged in developing stem cell derived models of the CNS in an attempt to study complex cellular interactions that occur in development and disease. 

Qualifications

2015                 Postgraduate certificate in professional practice, Aston University, Birmingham

2001-2004        PhD, Aston University, Birmingham

1997- 2000      BSc (Hons): Applied and Human Biology Aston University, Birmingham

Employment

  • 2018-Present Senior Lecturer, Aston University
  • 2014-2018 Lecturer, Aston University
  • 2010-2014 Postdoctoral research Fellow, ARCHA, Aston University
  • 2007-2010 Postdoctoral research fellow, Aston University
  • 2005-2007 Postdoctoral research fellow, Aston University
  • 2001-2004 PhD Aston University
  • 2000 Assistant forensic scientist, Forensic Science Service, Birmingham

Teaching Activity

Postgraduate teaching

Module Coordinator Stem cells and regenerative medicine

Module coordinator Ageing and regenerative medicine

 

Undergraduate teaching

Module coordinator Stem cell biology

Module coodinator Bioethics

 

PhD Supervision

2015-present                 Miss Sarah Alqattan, ‘Metabolic dysfunction in iPSC derived neurons and astrocytes’

2016-present                 Miss Marianne King, ‘Astrocyte dysfunction in Rett syndrome’.

Research Projects/Collaborations

Metabolic dysfunction in Alzheimer's disease

Astrocyte dysfunction in Rett syndrome

MESO-Brain: 3D Neural networks (https://www.mesobrain.eu/)

Seizure liability testing using iPSC derived neurons

Role of micorglia in Huntigton's disease

Professional/editorial offices

Associate editor Frontiers in Neuroscience, Neurodegeneration

Administrative Roles

Programme director Biosciences Postgraduate Programmes

Programme director MSc Stem cells and regenerative medicine

Contact Details

Email: hillej@aston.ac.uk
Tel: +44 (0) 1212045040

External positions

Chair of Equality Diversity Inclusion committee

Fingerprint Dive into the research topics where Eric Hill is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Astrocytes Medicine & Life Sciences
Neurons Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Poisons Medicine & Life Sciences
astrocytes Agriculture & Biology
Coculture Techniques Medicine & Life Sciences
Cells Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2007 2019

Distinct conformations, aggregation and cellular internalization of different tau strains

Karikari, T. K., Nagel, D. A., Grainger, A., Clarke-Bland, C., Crowe, J., Hill, E. J. & Moffat, K. G., 9 Jul 2019, In : Frontiers in Cellular Neuroscience. 13, 296.

Research output: Contribution to journalArticle

Open Access
File
Frontotemporal Dementia
Tauopathies
Induced Pluripotent Stem Cells
tau Proteins
Mutation

Preparation of stable tau oligomers for cellular and biochemical studies

Karikari, T. K., Nagel, D. A., Grainger, A., Clarke-bland, C., Hill, E. J. & Moffat, K. G., 1 Feb 2019, In : Analytical Biochemistry. 566, p. 67-74 8 p.

Research output: Contribution to journalArticle

Open Access
File
Oligomers
Tauopathies
Ethylmaleimide
Structure-Activity Relationship
Neuroblastoma

A closer look at neuron interaction with track-etched microporous membranes

George, J. H., Nagel, D., Waller, S., Hill, E., Parri, H. R., Coleman, M. D., Cui, Z. & Ye, H., 19 Oct 2018, In : Scientific Reports. 8, 1, 15552.

Research output: Contribution to journalArticle

Open Access
File
Neurites
Neurons
Membranes
Growth
Electron Scanning Microscopy

Downregulation of aquaporin 3 inhibits cellular proliferation, migration and invasion in the MDA‑MB‑231 breast cancer cell line

Arif, M., Kitchen, P., Conner, M., Hill, E., Nagel, D., Bill, R., Dunmore, S., Armesilla, A., Gross, S., Carmichael, A., Conner, A. & Brown, J., May 2018, In : Oncology Letters. 16, 1, p. 713-720

Research output: Contribution to journalArticle

Open Access
File
Aquaporin 3
Aquaporins
Aquaglyceroporins
Glycerol
Gene Knockdown Techniques

In vitro Models for Seizure-Liability Testing Using Induced Pluripotent Stem Cells

Grainger, A. I., King, M. C., Nagel, D. A., Parri, H. R., Coleman, M. D. & Hill, E. J., 31 Aug 2018, In : Frontiers in Neuroscience. 12, AUG, 590.

Research output: Contribution to journalReview article

Open Access
File
Induced Pluripotent Stem Cells
Seizures
Rodentia
Electrodes
Central Nervous System

Thesis

Aβ(1-42) induced metabolic effects in a stem cell derived neuron and astrocyte network.

Author: Tarczyluk, M., 30 Jul 2013

Supervisor: Parri, H. R. (Supervisor) & Hill, E. J. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Polarised secretion of leukaemia inhibitory factor

Author: Hill, E. J., Sep 2004

Supervisor: Vernallis, A. B. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

The role of amyloid precursor protein in neuronal and non-neuronal cell lines

Author: Tse, E., 3 Dec 2015

Supervisor: Hill, E. J. (Supervisor) & Parri, H. R. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Activities 2010 2013

  • 2 Participation in conference
  • 2 Participation in workshop, seminar, course

NC3Rs Annual Science Review meeting

Eric Hill (Participant)
26 Feb 2013

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

Alzheimer Research UK Annual Conference

Eric Hill (Organiser)
17 Apr 201218 Apr 2012

Activity: Participating in or organising an event typesParticipation in conference

Alzheimer's Research UK PhD day

Eric Hill (Participant)
16 Apr 2012

Activity: Participating in or organising an event typesParticipation in conference

British Science Festival

Eric Hill (Organiser)
15 Sep 2010

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course