Research output per year
Research output per year
Personal profile
Contact Details
Email: hillej@aston.ac.uk
Tel: +44 (0) 1212045040
Research Interests
My main research interests include the development of tissue engineering strategies to model stem cell behaviour in the development of neuronal networks and also during neurodegeneration. I am currently engaged in developing stem cell derived models of the CNS in an attempt to study complex cellular interactions that occur in development and disease.
Qualifications
2015 Postgraduate certificate in professional practice, Aston University, Birmingham
2001-2004 PhD, Aston University, Birmingham
1997- 2000 BSc (Hons): Applied and Human Biology Aston University, Birmingham
Employment
- 2018-Present Senior Lecturer, Aston University
- 2014-2018 Lecturer, Aston University
- 2010-2014 Postdoctoral research Fellow, ARCHA, Aston University
- 2007-2010 Postdoctoral research fellow, Aston University
- 2005-2007 Postdoctoral research fellow, Aston University
- 2001-2004 PhD Aston University
- 2000 Assistant forensic scientist, Forensic Science Service, Birmingham
Teaching Activity
Postgraduate teaching
Module Coordinator Stem cells and cellular differentiation
Module coordinator Ageing and regenerative medicine
Undergraduate teaching
Module coordinator Stem cell biology
Module coodinator Bioethics
PhD Supervision
2019-Present: Paige Walczak. ‘Development of a 3D model of the cortex for investigation of neurodegenerative diseases.
2016-2021: Marianne King, ‘Astrocyte dysfunction in Rett syndrome’.
2015-2019: Sarah Alqattan, ‘Metabolic dysfunction in iPSC derived neurons and astrocytes’
2012-2015: Erin Tse, ‘The role of Amyloid Precursor Protein in neuronal and non-neuronal cell lines.
2009-2012: Marta Tarczyluk, ‘Aβ1-42 induced metabolic effects in a stem cell derived model of Alzheimer’s Disease’.
Research Projects/Collaborations
Biological AI (https://neuchip.eu/)
Development of a 3D model of the cortex for investigation of neurodegenerative diseases. https://lifetime-cdt.org/
Metabolic dysfunction in Alzheimer's disease using iPSC
Astrocyte dysfunction in Rett syndrome using iPSC
MESO-Brain: 3D Neural networks (https://www.mesobrain.eu/)
Seizure liability testing using iPSC derived neurons
Role of micorglia in Huntigton's disease
Professional/editorial offices
Associate editor Frontiers in Neuroscience, Neurodegeneration
Member: British Neuroscience Association
Member: Biochemical Society
Administrative Roles
Programme director Biosciences Postgraduate Programmes
Programme director MSc Stem cells and regenerative medicine
Key research projects
NEU-CHiP: Taking complex biological computing into reality.
This is a grant funded by the EU.
The NEU-CHiP project is an international collaboration of leaders across a wide range of disciplines, with a shared focus to engineer and apply human neural cell circuits as biological computers.
External positions
Chair of Equality Diversity Inclusion committee
Fingerprint
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Advances in microfluidic in vitro systems for neurological disease modeling
Holloway, P. M., Willaime‐Morawek, S., Siow, R., Barber, M., Owens, R. M., Sharma, A. D., Rowan, W., Hill, E. & Zagnoni, M., May 2021, In: Journal of Neuroscience Research. 99, 5, p. 1276-1307 32 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Amyloid-β Precursor Protein Processing and Oxidative Stress are Altered in Human iPSC-Derived Neuron and Astrocyte Co-Cultures Carrying Presenillin-1 Gene Mutations Following Spontaneous Differentiation
Elsworthy, R. J., King, M. C., Grainger, A., Fisher, E., Crowe, J. A., Alqattan, S., Ludlam, A., Hill, D. E. J. & Aldred, S., 1 Jul 2021, In: Molecular and Cellular Neuroscience. 114, 103631.Research output: Contribution to journal › Article › peer-review
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Increased connectivity of hiPSC-derived neural networks in multiphase granular hydrogel scaffolds
Hsu, C., George, J. H., Waller, S., Besnard, C., Nagel, D. A., Hill, E. J., Coleman, M. D., Korsunsky, A. M., Cui, Z. & Ye, H., Mar 2022, In: Bioactive Materials. 9, p. 358-372 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Modelling the Central Nervous System: tissue engineering of the cellular microenvironment
Walczak, P., Perez Esteban, P., Bassett, D. & Hill, E., 29 Oct 2021, In: Emerging Topics in Life Sciences. 5, 4, p. 507-517 11 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Trabecular bone organoids: a micron-scale ‘humanised’ prototype designed to study the effects of microgravity and degeneration
Iordachescu, A., Hughes, E. A. B., Joseph, S., Hill, E. J., Grover, L. M. & Metcalfe, A. D., 21 May 2021, In: npj Microgravity. 7, 1, 17.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Thesis
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Polarised secretion of leukaemia inhibitory factor
Author: Hill, E. J., Sep 2004Supervisor: Vernallis, A. B. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
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NC3Rs Annual Science Review meeting
Eric Hill (Participant)
26 Feb 2013Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Alzheimer Research UK Annual Conference
Eric Hill (Organiser)
17 Apr 2012 → 18 Apr 2012Activity: Participating in or organising an event types › Participation in conference
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Alzheimer's Research UK PhD day
Eric Hill (Participant)
16 Apr 2012Activity: Participating in or organising an event types › Participation in conference
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British Science Festival
Eric Hill (Organiser)
15 Sep 2010Activity: Participating in or organising an event types › Participation in workshop, seminar, course