Electrophysiological studies on neurones of the entorhinal cortex (EC) and hippocampus.

The role of glutamate and GABA receptors in epilepsy in the brain; the role of homeodynamic synaptic scaling in epileptogenesis in the temporal lobe. Autoimmune epilepsies, psychosis and neuronal network dynamics; the relationaship between epilepsy and affective disorders. The role of cannabinoids in epilepsy tresatment (collabration with GW Pharma). The role of primary motor cortex in epilepsy and Parkinson’s disease (in collaboration with Dr. Stuart Greenhill)

The temporal lobe is a brain region which is especially prone to epilepsy. My research focuses on how epilepsy is established, and how dynamic changes in receptor expression and function leads to changes in neronal network behaviour that may underlie epileptic seizures. I am interested too, in how neuronal network dynamics alter in schizophrenia, and how epilepsy and schizophrenia relate to each other in terms of pathological network fnction.

PH2501: Antidysrhythmic drugs.
PH3601: Glutamate, drug abuse, epilepsy, general aAnaesthetics.
Course Director, BSc Neuroscience

NE2001: Key Skills n Neurosciences

NE1008: Practical studies in Neurosciences 1

NE2008: Practical studies in Neurosciences 2

NE2003: Systems Neuroscience

NE1009: PIlls and Poisons, toxins and their use in Neuroscience research

NE3010: Psychosis and schizophrenia

NE3008: Epilepsy and neuronal networks

• 1998–2002 Post-doctoral researcher, University of Bristol.
• 1995–1998 Postdoctoral fellow University of Montreal, Canada.
• 1994–1995 Postdoctoral Fellow University of Southampton.
• 1991–1994 PhD University of Southampton

Email: [email protected]
Telephone: +44 (0) 121 204 3995