Research output per year
Research output per year
Dr
Aston University, Aston Triangle
B4 7ET Birmingham
Accepting PhD Students
I joined Aston University in 2016 as a Lecturer in Microbiology in the School of Life & Health Sciences (LHS). Prior to that, I was a Research Fellow funded by the Tres Cantos Open Lab Foundation (TCOLF), operated by GlaxoSmithKline (GSK), Madrid under their Diseases in the Developing World directive. I was also previously a Research Associate in the Institute of Microbiology and Infection (IMI) at the University of Birmingham immediately after completing my Ph.D. in Molecular Microbiology and Drug Discovery under the supervision of Prof. Gurdyal Besra. Before that, I completed an undergraduate degree in Medical Biochemistry at University of Birmingham, where my interest in the biology and biochemistry of microorganisms began.
My research interests surround the discovery of new antibiotics and identifying the exact mechanism by which those antibiotics kill bacteria. Finding new “mechanisms of action” reveals new drug targets that can be exploited in the battle against antimicrobial resistance (AMR). AMR accounts for around 700,000 deaths per annum globally and that number is predicted to rise to 10 million by 2050. The current economic burden of AMR is estimated to be at least €1.5 billion per year in the EU. New antibiotics and an improved understanding of how to use them will help to slow the progression of AMR, saving countless lives in the future.
In my current role, I lead the Mycobacterial Research Group at Aston University. My group consists of three PhD students and one post-doctoral researcher, along with a number of master’s students and undergraduate students who decide to study with us. We are a multidisciplinary team with a diverse skill-set, spanning microbiology, biochemistry, molecular genetics, structural biology and drug discovery. Our main focus is to study the physiology of various pathogenic mycobacteria (such as Mycobacterium abscessus, Mycobacterium tuberculosis and Mycobacterium bovis) and to discover new ways to treat infections. By using the physiology to inform antibiotic drug discovery, we can develop new treatment regimens that are able to overcome factors contributing to antibiotic resistance in these highly antibiotic-tolerant bacteria. We collaborate with several other research groups around the UK, including The University of Bradford, University of Hertfordshire and University of Plymouth, as well as clinicians at Birmingham Children’s Hospital. I was recently interviewed by the Microbiology Society about my research. That interview is available here.
I also teach at Aston and currently lead teaching for first year microbiology on our Biomedical Science, Biology and Biochemistry courses, as well as contributing to teaching across other parts of our program. I currently serve as Biomedical Science Top Up Modules Course Director.
I regularly engage with the press to comment on news stories and issues related to microbiology, infectious diseases and antibiotic resistance. I have experience of both written and broadcast media. Further details of my media work is available here.
B.Sc. (Hons) Medical Biochemistry
Ph.D. Molecular Microbiology and Drug Discovery
Senior Fellow of the Higher Education Academy (SFHEA)
Fellow of the Institute of Biomedical Science (FIBMS)
Member of the Acid Fast Club, UK
Member of the Royal Society of Biology (MRSB)
Member of the Biochemical Society
Member of the Microbiology Society
Member of the British Society for Antimicrobial Chemotherapy (BSAC)
I am module coordinator for :
BB4MAG - First Year Microbiology and Genetics
BB6MAM - Final Year Molecular and Applied Microbiology.
I contribute to teaching on many other modules and am currently Biomedical Science Top Up Modules Course Director.
Tel: +44 (0) 121 204 5011
Email: [email protected]
Room: MB438C
Lab: MB327
Associate PhD Supervisor , Plymouth University, Peninsula Schools of Medicine and Dentistry
Sept 2018 → Sept 2021
Associate PhD Supervisor, University of Hertfordshire
Jul 2018 → Jul 2021
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Review article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review