Photo of Jonathan A. G. Cox
  • Phone01212045011
  • Aston University, Aston Triangle

    B4 7ET Birmingham

20122020

Research output per year

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Research Output

  • 15 Article
  • 3 Review article
  • 1 Meeting abstract
  • 1 Comment/debate
2020
Open Access
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Open Access

Effect of Amoxicillin in combination with Imipenem-Relebactam against Mycobacterium abscessus

Lopeman, R. C., Harrison, J., Rathbone, D., Desai, M., Lambert, P. & Cox, J. A. G., 27 Jan 2020, In : Scientific Reports. 10, 1, 928.

Research output: Contribution to journalArticle

Open Access
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Identification and validation of the mode of action of the chalcone anti-mycobacterial compounds

Anagani, B., Singh, J., Bassin, J. P., Besra, G. S., Benham, C., Reddy, T. R. K., Cox, J. A. G. & Goyal, M., 18 May 2020, In : The Cell Surface. 6, 100041.

Research output: Contribution to journalArticle

Open Access
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Open Access
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2019

Changing the Rules of TB-Drug Discovery

Harrison, J. & Cox, J. A. G., 12 Dec 2019, In : Journal of Medicinal Chemistry. 62, 23, p. 10583-10585 3 p.

Research output: Contribution to journalArticle

Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation

Cox, J. A. G., Taylor, R. C., Brown, A. K., Attoe, S., Besra, G. S. & Fütterer, K., 1 Jan 2019, In : Acta Crystallographica Section D: Structural Biology. 75, Pt 1, p. 101-108 8 p.

Research output: Contribution to journalArticle

Open Access
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Dissecting the Antimicrobial Composition of Honey

Nolan, V. C., Harrison, J. & Cox, J. A. G., 5 Dec 2019, In : Antibiotics. 8, 4, 251.

Research output: Contribution to journalReview article

Open Access
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Mycobacterium abscessus: Environmental Bacterium Turned Clinical Nightmare

Lopeman, R. C., Harrison, J., Desai, M. & Cox, J. A. G., 22 Mar 2019, In : Microorganisms. 7, 3, 90.

Research output: Contribution to journalReview article

Open Access
File
2018

Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets

Trofimov, V., Kicka, S., Mucaria, S., Hanna, N., Ramon-Olayo, F., Del Peral, L. V. G., Lelièvre, J., Ballell, L., Scapozza, L., Besra, G. S., Cox, J. A. G. & Soldati, T., 2 Mar 2018, In : Scientific Reports. 8, 1, 3939.

Research output: Contribution to journalArticle

Open Access
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Modelling a silent epidemic: A review of the in vitro models of latent tuberculosis

Gibson, S. E. R., Harrison, J. & Cox, J. A. G., 15 Nov 2018, In : Pathogens. 7, 4, 88.

Research output: Contribution to journalReview article

Open Access
File
2017

Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface

Abrahams, K. A., Cox, J. A. G., Fütterer, K., Rullas, J., Ortega-Muro, F., Loman, N. J., Moynihan, P. J., Pérez-Herrán, E., Jiménez, E., Esquivias, J., Barros, D., Ballell, L., Alemparte, C. & Besra, G. S., 25 Aug 2017, In : Scientific Reports. 7, 15 p., 9430.

Research output: Contribution to journalArticle

Open Access
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The 'Antibiotic Apocalypse' - scaremongering or scientific reporting?

Cox, J. A. G. & Worthington, T., 1 Mar 2017, In : Trends in Microbiology. 25, 3, p. 167-169 3 p.

Research output: Contribution to journalArticle

Open Access
File
2016

Drug development: the cell wall as a drug target

Cox, J. A. G., Dec 2016, In : International Journal of Mycobacteriology. 5, Supplement 1, p. S156 1 p.

Research output: Contribution to journalConference abstract

Open Access
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Identification of KasA as the cellular target of an anti-tubercular scaffold

Abrahams, K. A., Chung, C-W., Ghidelli-Disse, S., Rullas, J., Rebollo-López, M. J., Gurcha, S. S., Cox, J. A. G., Mendoza, A., Jiménez-Navarro, E., Martínez-Martínez, M. S., Neu, M., Shillings, A., Homes, P., Argyrou, A., Casanueva, R., Loman, N. J., Moynihan, P. J., Lelièvre, J., Selenski, C., Axtman, M. & 10 others, Kremer, L., Bantscheff, M., Angulo-Barturen, I., Izquierdo, M. C., Cammack, N. C., Drewes, G., Ballell, L., Barros, D., Besra, G. S. & Bates, R. H., 1 Sep 2016, In : Nature Communications. 7, 13 p., 12581.

Research output: Contribution to journalArticle

Open Access
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Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen

Cox, J. A. G., Mugumbate, G., Vela-Glez del Peral, L., Jankute, M., Abrahams, K. A., Jervis, P., Jackenkroll, S., Perez, A., Alemparte, C., Esquivias, J., Lelièvre, J., Ramon, F., Barros, D., Ballell, L. & Besra, G. S., 16 Dec 2016, In : Scientific Reports. 6, 10 p., 38986.

Research output: Contribution to journalArticle

Open Access
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THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria

Cox, J. A. G., Abrahams, K. A., Alemparte, C., Ghidelli-Disse, S., Rullas, J., Angulo-Barturen, I., Singh, A., Gurcha, S. S., Nataraj, V., Bethell, S., Remuiñán, M. J., Encinas, L., Jervis, P. J., Cammack, N. C., Bhatt, A., Kruse, U., Bantscheff, M., Fütterer, K., Barros, D., Ballell, L. & 2 others, Drewes, G. & Besra, G. S., 18 Jan 2016, In : Nature Microbiology. 1, 15006.

Research output: Contribution to journalArticle

Open Access
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2015

Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation.

Mugumbate, G., Abrahams, KA., Cox, JA., Papadatos, G., van, W. G., Lelièvre, J., Calus, ST., Loman, NJ., Ballell, L., Barros, D., Overington, JP. & Besra, GS., 23 Mar 2015, In : PLoS ONE. 10, 3, e0121492.

Research output: Contribution to journalArticle

Open Access
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2014

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target.

Gurcha, SS., Usha, V., Cox, JA., Fütterer, K., Abrahams, KA., Bhatt, A., Alderwick, LJ., Reynolds, RC., Loman, NJ., Nataraj, V., Alemparte, C., Barros, D., Lloyd, AJ., Ballell, L., Hobrath, JV. & Besra, GS., 19 Nov 2014, In : PLoS ONE. 9, 11, e113568.

Research output: Contribution to journalArticle

Open Access
File
2012

Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB.

Abrahams, KA., Cox, JA., Spivey, VL., Loman, NJ., Pallen, MJ., Constantinidou, C., Fernández, R., Alemparte, C., Remuiñán, MJ., Barros, D., Ballell, L. & Besra, GS., 31 Dec 2012, In : PLoS ONE. 7, 12, e52951.

Research output: Contribution to journalArticle

Open Access
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