Personal profile
Biography
Dr Usmari Moraes has years of experience in the field of redox biochemistry and metabolic dysregulation in neurodegeneration. With previous work showing the metabolic changes in type 2 diabetes involved in Alzheimer's development, her research now focuses on understanding signaling mechanisms surrounding thrombus formation and Parkinson's disease.
Membership of Professional Bodies
Biochemical Society - Early Career Member (2021 - Current)
British Society for Research on Ageing - Member (2024 - Current)
Education/Academic qualification
PhD, Metabolic dysregulation and the role of the BCAT protein - implications for type 2 diabetes and Alzheimer's disease, University of the West of England
2018 → 2023
BSc, Distribution of the BCATm, BCKDH E1a and GDH in the human brain and their role in neurometabolism, University of the West of England
2013 → 2017
Keywords
- QP Physiology
- Thrombosis
- Parkinson's disease
- Platelets
- Endothelial cells
- Neuroinflammation
- Alzheimer's disease
- Metabolic syndrome
- Neurodegeneration
- Redox Biochemistry
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Research output
- 3 Article
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BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease
Harris, M., El Hindy, M., Usmari Moraes, M., Hudd, F., Shafei, M., Dong, M., Hezwani, M., Clark, P., House, M., Forshaw, T., Kehoe, P. & Conway, M. E., 20 May 2020, In: Free Radical Biology and Medicine. 152, p. 755-766 11 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Link opens in a new tab Citations (SciVal) -
Immunotherapeutic and pharmacological approaches for the treatment of Alzheimer’s disease
Usmari Moraes, M. & Gaudet, T. J., 12 Apr 2018, In: Bioscience Horizons: The International Journal of Student Research. 11, p. 1-7Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Citations (Scopus) -
Distribution of the branched-chain α-ketoacid dehydrogenase complex E1α subunit and glutamate dehydrogenase in the human brain and their role in neuro-metabolism
Hull, J., Usmari Moraes, M., Brookes, E., Love, S. & Conway, M., Jan 2018, In: Neurochemistry International. 112, p. 49-58 9 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Link opens in a new tab Citations (SciVal)