Research Output per year
Personal profile
Qualifications
PhD in "Human Biology: cellular and molecular bases", University of Torino, Italy
MSc in Biological Sciences, University of Torino, Italy
Research Interests
My research focuses on understanding the molecular and cellular mechanisms leading to neuronal death and neurodegeneration in central nervous system diseases. I am particularly interested in mechanisms underlying Parkinson’s disease by elucidating the cellular functions of DJ-1 – a protein linked to rare inherited forms of Parkinson’s. This work may ultimately provide insight into novel therapeutic strategies for this disorder.
Teaching Activity
Undergraduate modules
BY1DA1 Development and Human Anatomy
BY1HP1 Physiology for Biologists
Contact Details
Telephone: 0121 204 5219
Email: m.repici@aston.ac.uk
External positions
Wellcome-Trust Institutional Strategic Support Fund (WT-ISSF) Fellow, University of Leicester
Sep 2018 → Feb 2019Research Associate, University of Leicester
Oct 2009 → Aug 2018Post-doctoral position
Jan 2007 → Sep 2009Post doctoral fellowship , Université de Lausanne
Jun 2004 → Dec 2006Fingerprint Dive into the research topics where Mariaelena Repici is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 5 Similar Profiles
JNK Mitogen-Activated Protein Kinases
Medicine & Life Sciences
Neurons
Medicine & Life Sciences
Parkinson Disease
Medicine & Life Sciences
Geniculate Bodies
Medicine & Life Sciences
Caspase 3
Medicine & Life Sciences
Cell Death
Medicine & Life Sciences
Brain Ischemia
Medicine & Life Sciences
Phosphotransferases
Medicine & Life Sciences
Research Output 2006 2019
DJ-1 in Parkinson’s Disease: Clinical Insights and Therapeutic Perspectives
Repici, M. & Giorgini, F., 3 Sep 2019, In : Journal of clinical Medicine . 8, 9, 1377.Research output: Contribution to journal › Review article
Open Access
File
Parkinson Disease
Therapeutics
Brain
Oxidative Stress
Biomarkers
The Parkinson's Disease-Linked Protein DJ-1 Associates with Cytoplasmic mRNP Granules During Stress and Neurodegeneration
Repici, M., Hassanjani, M., Maddison, D. C., Garção, P., Cimini, S., Patel, B., Szegö, É. M., Straatman, K. R., Lilley, K. S., Borsello, T., Outeiro, T. F., Panman, L. & Giorgini, F., 1 Jan 2019, In : Molecular Neurobiology. 56, 1, p. 61-77 17 p.Research output: Contribution to journal › Article
Open Access
File
Cytoplasmic Granules
Parkinson Disease
Oxidative Stress
RNA
Messenger RNA
Adaptive and Behavioral Changes in Kynurenine 3-Monooxygenase Knockout Mice: Relevance to Psychotic Disorders
Erhardt, S., Pocivavsek, A., Repici, M., Liu, X-C., Imbeault, S., Maddison, D. C., Thomas, M. A. R., Smalley, J. L., Larsson, M. K., Muchowski, P. J., Giorgini, F. & Schwarcz, R., 15 Nov 2017, In : Biological Psychiatry. 82, 10, p. 756-765 10 p.Research output: Contribution to journal › Article
Open Access
File
Kynurenine 3-Monooxygenase
Knockout Mice
Psychotic Disorders
Kynurenic Acid
Kynurenine
Copy-number variation of the neuronal glucose transporter gene SLC2A3 and age of onset in Huntington's disease
15 Jun 2014, In : Human Molecular Genetics. 23, 12, p. 3129-3137 9 p.Research output: Contribution to journal › Article
Open Access
File
Facilitative Glucose Transport Proteins
Huntington Disease
Age of Onset
Genes
Trinucleotide Repeat Expansion
DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson's disease
Zondler, L., Miller-Fleming, L., Repici, M., Gonçalves, S., Tenreiro, S., Rosado-Ramos, R., Betzer, C., Straatman, K. R., Jensen, P. H., Giorgini, F. & Outeiro, T. F., 24 Jul 2014, In : Cell Death and Disease. 5, e1350.Research output: Contribution to journal › Article
Open Access
File
Synucleins
Parkinson Disease
Mutation
Lewy Bodies
Neurons