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Research Output 1997 2019

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Article
1997
Fibrosarcoma
Cricetinae
Cell Cycle
Apoptosis
Drug Therapy

The role of transglutaminase in the rat subtotal nephrectomy model of renal fibrosis

Johnson, T. S., Griffin, M., Thomas, G. L., Skill, J., Cox, A., Bin Yang, B., Nicholas, B., Birckbichler, P. J., Muchaneta-Kubara, C. & El Nahas, A. M., 15 Jun 1997, In : Journal of Clinical Investigation. 99, 12, p. 2950-2960 11 p.

Research output: Contribution to journalArticle

Open Access
File
Transglutaminases
Nephrectomy
Fibrosis
Kidney
Extracellular Matrix Proteins
1999

Transglutaminase transcription and antigen translocation in experimental renal scarring

Johnson, T. S., Skill, N. J., El Nahas, A. M., Oldroyd, S. D., Thomas, G. L., Douthwaite, J. A., Haylor, J. L. & Griffin, M., Oct 1999, In : Journal of the American Society of Nephrology. 10, 10, p. 2146-2157 12 p.

Research output: Contribution to journalArticle

Transglutaminases
Cicatrix
Kidney
Antigens
Lysine
2001

Characterization of tissue transglutaminase in human osteoblast-like cells

Heath, D. J., Downes, S., Verderio, E. & Griffin, M., Aug 2001, In : Journal of Bone and Mineral Research. 16, 8, p. 1477-1485 9 p.

Research output: Contribution to journalArticle

Osteoblasts
Transglutaminases
Cadaverine
Putrescine
Extracellular Matrix Proteins

Decreased efficiency of trypsinization of cells following photodynamic therapy: evaluation of a role for tissue transglutaminase

Ball, D. J., Mayhew, S., Vernon, D. I., Griffin, M. & Brown, S. B., 2001, In : Photochemistry and Photobiology. 73, 1, p. 47-53 7 p.

Research output: Contribution to journalArticle

Photodynamic therapy
Photochemotherapy
therapy
evaluation
fluence

Increases in renal ε-(γ-glutamyl)-lysine crosslinks result from compartment-specific changes in tissue transglutaminase in early experimental diabetic nephropathy: Pathologic implications

Skill, N. J., Griffin, M., El Nahas, A. M., Sanai, T., Haylor, J. L., Fisher, M., Jamie, M. F., Mould, N. N. & Johnson, T. S., May 2001, In : Laboratory Investigation. 81, 5, p. 705-716 12 p.

Research output: Contribution to journalArticle

Diabetic Nephropathies
Lysine
Transglutaminases
Kidney
Extracellular Matrix

Job satisfaction and teamwork: The role of supervisor support

Griffin, M. A., Patterson, M. & West, M. A., Aug 2001, In : Journal of Organizational Behavior. 22, 5, p. 537-550 14 p.

Research output: Contribution to journalArticle

Job Satisfaction
teamwork
job satisfaction
Multilevel Analysis
job enrichment
2002
Open Access
File
Fibroblasts
Cell Movement
Conformations
Enzymes
Extracellular Matrix

Biocomposites of non-crosslinked natural and synthetic polymers

Coombes, A. G. A., Verderio, E., Shaw, B., Li, X., Griffin, M. & Downes, S., May 2002, In : Biomaterials. 23, 10, p. 2113-2118 6 p.

Research output: Contribution to journalArticle

Collagen
Polymers
Osteoblasts
Biocompatible Materials
Biomaterials

Involvement of tissue transglutaminase in the stabilisation of biomaterial/tissue interfaces important in medical devices

Heath, D. J., Christian, P. & Griffin, M., Mar 2002, In : Biomaterials. 23, 6, p. 1519-1526 8 p.

Research output: Contribution to journalArticle

Biocompatible Materials
Biomaterials
Fibronectins
Stabilization
Tissue

The biotechnological applications of transglutaminases

Collighan, R., Cortez, J. & Griffin, M., Jun 2002, In : Minerva Biotecnologica. 14, 2, p. 143-148 6 p.

Research output: Contribution to journalArticle

Transglutaminases
Enzymes
Biocatalysts
Cosmetics
Textile industry

Transglutaminase overexpression sensitizes neuronal cell lines to apoptosis by increasing mitochondrial membrane potential and cellular oxidative stress

Piacentini, M., Farrace, M. G., Piredda, L., Matarrese, P., Ciccosanti, F., Falasca, L., Rodolfo, C., Giammarioli, A. M., Verderio, E., Griffin, M. & Malorni, W., Jun 2002, In : Journal of Neurochemistry. 81, 5, p. 1061-1072 12 p.

Research output: Contribution to journalArticle

Transglutaminases
Oxidative stress
Mitochondrial Membrane Potential
Oxidative Stress
Cells

Transglutaminases: nature's biological glues

Griffin, M., Casadio, R. & Bergamini, C. M., 1 Dec 2002, In : Biochemical Journal. 368, Pt 2, p. 377-396 20 p.

Research output: Contribution to journalArticle

Open Access
Transglutaminases
Glues
Adhesives
Enzymes
Tissue
2003

A novel RGD-independent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis

Verderio, E. A. M., Telci, D., Okoye, A., Melino, G. & Griffin, M., 24 Oct 2003, In : Journal of Biological Chemistry. 278, 43, p. 42604-42614 11 p.

Research output: Contribution to journalArticle

Open Access
File
Anoikis
Fibronectins
Adhesion
Cell adhesion
Cell Adhesion

Cross-linking of cellular proteins by tissue transglutaminase during necrotic cell death: a mechanism for maintaining tissue integrity

Nicholas, B., Smethurst, P., Verderio, E., Jones, R. & Griffin, M., Apr 2003, In : Biochemical Journal. 371, 2, p. 413-422 10 p.

Research output: Contribution to journalArticle

Open Access
Cell death
Cell Death
Tissue
Proteins
Electroporation
Cell death
Fibroblasts
Extracellular Matrix
Repair
Cell Death

Novel approach to improving enzyme penetration

Senior, K., Griffin, M. & Collighan, R., Jan 2003, British Leather Technology Centre journal, 46.

Research output: Contribution to specialist publicationArticle

Tissue transglutaminase and the progression of human renal scarring

Johnson, T. S., El-Koraie, A. F., Skill, N. J., Baddour, N. M., El Nahas, A. M., Njloma, M., Adam, A. G. & Griffin, M., 1 Aug 2003, In : Journal of the American Society of Nephrology. 14, 8, p. 2052-2062 11 p.

Research output: Contribution to journalArticle

Cicatrix
Kidney
Chronic Renal Insufficiency
Lysine
Extracellular Matrix

Transglutaminases in the leather industry

Collighan, R. & Griffin, M., Jan 2003, British Leather Technology Centre journal, 46.

Research output: Contribution to specialist publicationArticle

2004

Activation of ERK1/2, JNK and PKB by hydrogen peroxide in human SH-SY5Y neuroblastoma cells: role of ERK1/2 in H2O2-induced cell death

Ruffels, J., Griffin, M. & Dickenson, J. M., 12 Jan 2004, In : European Journal of Pharmacology. 483, 2-3, p. 163-173 11 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-akt
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
Neuroblastoma
Hydrogen Peroxide

Activation of protein kinase B by adenosine A1 and A3 receptors in newborn rat cardiomyocytes

Germack, R., Griffin, M. & Dickenson, J. M., Nov 2004, In : Journal of Molecular and Cellular Cardiology. 37, 5, p. 989-999 11 p.

Research output: Contribution to journalArticle

Adenosine A3 Receptors
Adenosine A1 Receptors
Proto-Oncogene Proteins c-akt
Cardiac Myocytes
Adenosine

An improved colorimetric assay for the measurement of transglutaminase (type II) ε-(γ-glutamyl) lysine cross-linking activity

Trigwell, S. M., Lynch, P. T., Griffin, M., Hargreaves, A. J. & Bonner, P. L. R., 1 Jul 2004, In : Analytical Biochemistry. 330, 1, p. 164-166 3 p.

Research output: Contribution to journalArticle

Open Access
File

Application of transglutaminases in the modification of wool textiles

Cortez, J., Bonner, P. L. R. & Griffin, M., 5 Jan 2004, In : Enzyme and Microbial Technology. 34, 1, p. 64-72 9 p.

Research output: Contribution to journalArticle

Transglutaminases
Wool
Textiles
Amines
Yarn

Elevated ε-(γ-glutamyl)lysine in human diabetic nephropathy results from increased expression and cellular release of tissue transglutaminase

El Nahas, A. M., Abo-Zenah, H., Skill, N. J., Bex, S., Wild, G., Griffin, M. & Johnson, T. S., Jul 2004, In : Nephron Clinical Practice. 97, 3, p. 108-117 10 p.

Research output: Contribution to journalArticle

Diabetic Nephropathies
Lysine
Kidney
Extracellular Matrix
Confocal Microscopy

Inhibition of transglutaminase activity reduces extracellular matrix accumulation induced by high glucose levels in proximal tubular epithelial cells

Skill, N. J., Johnson, T. S., Coutts, I. G. . C., Saint, R. E., Fisher, M., Huang, L., El Nahas, A. M., Collighan, R. & Griffin, M., 12 Nov 2004, In : Journal of Biological Chemistry. 279, 46, p. 47754-47762 9 p.

Research output: Contribution to journalArticle

Open Access
File
Transglutaminases
Extracellular Matrix
Epithelial Cells
Glucose
Collagen

Role of transglutaminase 1 in stabilisation of intercellular junctions of the vascular endothelium

Baumgartner, W., Golenhofen, N., Weth, A., Hiiragi, T., Saint, R., Griffin, M. & Drenckhahn, D., Jul 2004, In : Histochemistry and Cell Biology. 122, 1, p. 17-25 9 p.

Research output: Contribution to journalArticle

Intercellular Junctions
Vascular Endothelium
Cytochalasin D
Lung
Endothelial Cells

Tissue transglutaminase: a mediator and predictor of chronic allograft nephropathy?

Johnson, T. S., Abo-Zenah, H., Skill, J. N., Bex, S., Wild, G., Brown, C. B., Griffin, M. & El Nahas, A. M., 15 Jun 2004, In : Transplantation. 77, 11, p. 1667-1675 9 p.

Research output: Contribution to journalArticle

Allografts
Kidney
Biopsy
Fibrosis
Staining and Labeling

Transglutaminases as tanning agents for the leather industry

Collighan, R., Clara, S., Li, X., Parry, J. & Griffin, M., Jul 2004, In : Journal of the American Leather Chemists Association. 99, 7, p. 293-302 10 p.

Research output: Contribution to journalArticle

Tanning
Transglutaminases
Leather
Crosslinking
Collagen
2005

Enzymatic stabilization of gelatin-based scaffolds

Broderick, E. P., O'Halloran, D. M., Rochev, Y. A., Griffin, M., Collighan, R. & Pandit, A. S., 15 Jan 2005, In : Journal of biomedical materials research: part B. 72, 1, p. 37-42 6 p.

Research output: Contribution to journalArticle

Transglutaminases
Gelatin
Scaffolds
Gels
Stabilization

The cellular response to transglutaminase-cross-linked collagen

Chau, D. Y. S., Collighan, R., Verderio, E. A. M., Addy, V. L. & Griffin, M., Nov 2005, In : Biomaterials. 26, 33, p. 6518-6529 12 p.

Research output: Contribution to journalArticle

Transglutaminases
Collagen
Osteoblasts
Collagen Type I
Foreskin

Transglutaminase and vascular biology: physiopathologic implications and perspectives for therapeutic interventions

Bergamini, C. M., Griffin, M. & Pansini, F. S., 2005, In : Current Medicinal Chemistry. 12, 20, p. 2357-2372 16 p.

Research output: Contribution to journalArticle

Transglutaminases
Matrix Metalloproteinases
Blood Vessels
Endothelial cells
Blood Coagulation

Transglutaminase treatment of wool fabrics leads to resistance to detergent damage

Cortez, J., Bonner, P. L. R. & Griffin, M., 6 Apr 2005, In : Journal of Biotechnology. 116, 4, p. 379-386 8 p.

Research output: Contribution to journalArticle

Transglutaminases
Wool
Detergents
Laundries
Clothing

Unexpected role of surface transglutaminase type II in celiac disease

Maiuri, L., Ciacci, C., Ricciardelli, I., Vacca, L., Raia, V., Rispo, A., Griffin, M., Issekutz, T., Quaratino, S. & Londei, M., Nov 2005, In : Gastroenterology. 129, 5, p. 1400-1413 14 p.

Research output: Contribution to journalArticle

Celiac Disease
Gliadin
Organ Culture Techniques
T-Lymphocytes
Toxic Actions
2006

Characterization of a microbial transglutaminase cross-linked type II collagen scaffold

O Halloran, D. M., Collighan, R., Griffin, M. & Pandit, A. S., 17 Jul 2006, In : Tissue Engineering. 12, 6, p. 1467-1474 8 p.

Research output: Contribution to journalArticle

Transglutaminases
Collagen Type II
Scaffolds
Scaffolds (biology)
Covalent bonds

Matrix changes induced by transglutaminase 2 lead to inhibition of angiogenesis and tumor growth

Jones, R. A., Kotsakis, P., Johnson, T. S., Chau, D. Y. S., Ali, S., Melino, G. & Griffin, M., Sep 2006, In : Cell Death and Differentiation. 13, 9, p. 1442-1453 12 p.

Research output: Contribution to journalArticle

Growth
Neoplasms
Extracellular Matrix
Matrix Metalloproteinase 1
Inhibition (Psychology)

The role of tissue transglutaminase in 1-methyl-4-phenylpyridinium (MPP+)-induced toxicity in differentiated human SH-SY5Y neuroblastoma cells

Beck, K. E., De Girolamo, L. A., Griffin, M. & Billett, E. E., 11 Sep 2006, In : Neuroscience Letters. 405, 1-2, p. 46-51 6 p.

Research output: Contribution to journalArticle

Open Access
File
1-Methyl-4-phenylpyridinium
Neuroblastoma
Transglutaminases
Polyamines
Proteins

Tissue transglutaminase (TG2) - a wound response enzyme

Telci, D. & Griffin, M., 1 Jan 2006, In : Frontiers in Bioscience. 11, 1, p. 867-882 16 p.

Research output: Contribution to journalArticle

Wound Healing
Repair
Extracellular Matrix
Transglutaminases
Wounds and Injuries
2007

Assessment of cell viability in a three-dimensional enzymatically cross-linked collagen scaffold

Garcia, Y., Collighan, R., Griffin, M. & Pandit, A. S., Oct 2007, In : Journal of Materials Science : Materials in Medicine. 18, 10, p. 1991-2001 11 p.

Research output: Contribution to journalArticle

Scaffolds (biology)
Collagen
Scaffolds
Cell Survival
Cells

Tissue transglutaminase and the stress response

Ientile, R., Caccamo, D. & Griffin, M., Aug 2007, In : Amino Acids. 33, 2, p. 385-394 10 p.

Research output: Contribution to journalArticle

Transglutaminases
Enzymes
Oxidative stress
Cross Reactions
Cell death

Tissue transglutaminase in tumour progression: Friend or foe?

Kotsakis, P. & Griffin, M., Aug 2007, In : Amino Acids. 33, 2, p. 373-384 12 p.

Research output: Contribution to journalArticle

Tumors
Neoplasms
Military electronic countermeasures
Biological Phenomena
transglutaminase 2

Transglutaminase inhibition reduces fibrosis and preserves function in experimental chronic kidney disease

Johnson, T. S., Fisher, M., Haylor, J. L., Hau, Z., Skill, N. J., Jones, R., Saint, R., Coutts, I. G. C., Vickers, M. E., El Nahas, A. M. & Griffin, M., Dec 2007, In : Journal of the American Society of Nephrology. 18, 12, p. 3078-3088 11 p.

Research output: Contribution to journalArticle

Transglutaminases
Chronic Renal Insufficiency
Fibrosis
Extracellular Matrix
Collagen

Transglutaminase mediated grafting of silk proteins onto wool fabrics leading to improved physical and mechanical properties

Cortez, J., Anghieri, A., Bonner, P. L. R., Griffin, M. & Freddi, G., 1 Jun 2007, In : Enzyme and Microbial Technology. 40, 7, p. 1698-1704 7 p.

Research output: Contribution to journalArticle

Transglutaminases
Silk
Wool
Sericins
Physical properties
2008

Bottom-up risk regulation? How nanotechnology risk knowledge gaps challenge federal and state environmental agencies

Powell, M. C., Griffin, M. P. A. & Tai, S., Sep 2008, In : Environmental Management. 42, 3, p. 426-443 18 p.

Research output: Contribution to journalArticle

nanotechnology
Nanotechnology
environmental risk
toxic substance
emission control

Fibronectin-tissue transglutaminase matrix rescues RGD-impaired celladhesion through syndecan-4 and β integrin co-signaling

Telci, D., Wang, Z., Li, X., Verderio, E. A. M., Humphries, M. J., Baccarini, M., Basaga, H. & Griffin, M., 25 Jul 2008, In : Journal of Biological Chemistry. 283, 30, p. 20937-20947 11 p.

Research output: Contribution to journalArticle

Open Access
File
Syndecan-4
Fibronectins
Integrins
Proto-Oncogene Proteins c-raf
Protein Kinases

Synthesis of potent water-soluble tissue transglutaminase inhibitors

Griffin, M., Mongeot, A., Collighan, R., Saint, R. E., Jones, R. A., Coutts, I. G. C. & Rathbone, D. L., 15 Oct 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 20, p. 5559-5562 4 p.

Research output: Contribution to journalArticle

Diazooxonorleucine
Lead compounds
Transglutaminases
Dipeptides
Water

Towards development of a dermal rudiment for enhanced wound healing response

Garcia, Y., Wilkins, B., Collighan, R., Griffin, M. & Pandit, A. S., Mar 2008, In : Biomaterials. 29, 7, p. 857-868 12 p.

Research output: Contribution to journalArticle

Collagen
Scaffolds
Wound Healing
Re-Epithelialization
Transglutaminases
2009

Celiac disease IgA modulates vascular permeability in vitro through the activity of transglutaminase 2 and RhoA

Myrsky, E., Caja, S., Simon-Vecsei, Z., Korponay-Szabo, I. R., Nadalutti, C., Collighan, R., Mongeot, A., Griffin, M., Mäki, M., Kaukinen, K. & Lindfors, K., Oct 2009, In : Cellular and Molecular Life Sciences. 66, 20, p. 3375-85 11 p.

Research output: Contribution to journalArticle

Capillary Permeability
Celiac Disease
Autoantibodies
Immunoglobulin A
Endothelium
File
NF-kappa B
Transforming Growth Factors
Transforming Growth Factor beta
Nitric Oxide
Fibroblasts

In vitro characterization of a collagen scaffold enzymatically cross-linked with a tailored elastin-like polymer

Garcia, Y., Hemantkumar, N., Collighan, R., Griffin, M., Rodriguez-Cabello, J. C. & Pandit, A., 10 Jul 2009, In : Tissue Engineering: Parts A, B and C. 15, 4, p. 887-899 13 p.

Research output: Contribution to journalArticle

Elastin
Scaffolds (biology)
Collagen
Scaffolds
Polymers

Modulation of tissue transglutaminase in tubular epithelial cells alters extracellular matrix levels: a potential mechanism of tissue scarring

Fisher, M., Jones, R. A., Huang, L., Haylor, J. L., El Nahas, M., Griffin, M. & Johnson, T. S., Jan 2009, In : Matrix Biology. 28, 1, p. 20-31 12 p.

Research output: Contribution to journalArticle

Cicatrix
Extracellular Matrix
Epithelial Cells
Collagen
Lysine