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Research Output 2000 2020

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2019

Toxicity bioassay of waste cooking oil-based biodiesel on marine microalgae

Pikula, K. S., Zakharenko, A. M., Chaika, V. V., Stratidakis, A. K., Kokkinakis, M., Waissi, G., Rakitskii, V. N., Sarigiannis, D. A., Hayes, A. W., Coleman, M. D., Tsatsakis, A. & Golokhvast, K. S., 1 Jan 2019, In : Toxicology Reports. 6, p. 111-117 7 p.

Research output: Contribution to journalArticle

Open Access
File
Microalgae
Biofuels
Bioassay
Cooking
Biological Assay
2018

A closer look at neuron interaction with track-etched microporous membranes

George, J. H., Nagel, D., Waller, S., Hill, E., Parri, H. R., Coleman, M. D., Cui, Z. & Ye, H., 19 Oct 2018, In : Scientific Reports. 8, 1, 15552.

Research output: Contribution to journalArticle

Open Access
File
Neurites
Neurons
Membranes
Growth
Electron Scanning Microscopy

Improved General and Oral Health in Diabetic Patients by an Okinawan-Based Nordic Diet: A Pilot Study

Holmer, H., Widén, C., Wallin Bengtsson, V., Coleman, M., Wohlfart, B., Steen, S., Persson, R. & Sjöberg, K., 3 Jul 2018, In : International Journal of Molecular Sciences. 19, 7, 1949.

Research output: Contribution to journalArticle

Open Access
File
diets
Oral Health
Nutrition
health
Health

Physiological and anthocyanin biosynthesis genes response induced by vanadium stress in mustard genotypes with distinct photosynthetic activity

Imtiaz, M., Mushtaq, M., Nawaz, M., Ashraf, M., Rizwan, M., Mehmood, S., Aziz, O., Rizwan, M., Virk, M., Shakeel, Q., Ijaz, R., Androutsopoulos, V., Tsatsakis, A. & Coleman, M., 13 Jun 2018, In : Environmental Toxicology and Pharmacology. 62, p. 20-29

Research output: Contribution to journalArticle

Open Access
File
Vanadium
Mustard Plant
Anthocyanins
Biosynthesis
Genes

Short-term effects of very low dose cadmium feeding on copper, manganese and iron homeostasis: A gastropod perspective

Nica, D. V., Draghici, G. A., Andrica, F., Popescu, S., Coricovac, D. E., Dehelean, C. A., Gergen, I. I., Kovatsi, L., Coleman, M. D. & Tsatsakis, A., 28 Oct 2018, In : Environmental Toxicology and Pharmacology.

Research output: Contribution to journalArticle

Open Access
File
Gastropoda
Manganese
Cadmium
Copper
Homeostasis

Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models

Seremet, O., Olaru, O., Gutu, C., Nitulescu, G., Ilie, M., Negres, S., Zbarcea, C., Purdel, C., Spandidos, D., Tsatsakis, A., Coleman, M. & Margina, D., 27 Mar 2018, In : Molecular Medicine Reports. 17, 6, p. 7757-7763

Research output: Contribution to journalArticle

Open Access
File
Pyrrolizidine Alkaloids
Plant Extracts
Invertebrates
Toxicity
Aquatic organisms
Open Access
File
efavirenz
Antimalarials
Drug Interactions
Pharmacokinetics
Ritonavir
2016

Systemic inflammatory impact of periodontitis on acute coronary syndrome

Widén, C., Holmer, H., Coleman, M., Tudor, M., Ohlsson, O., Sättlin, S., Renvert, S. & Persson, G. R., Sep 2016, In : Journal of Clinical Periodontology. 43, 9, p. 713-719 7 p.

Research output: Contribution to journalArticle

Open Access
File
Periodontitis
Acute Coronary Syndrome
Cytokines
Serum
Comorbidity
2015

Amyloid β 1-42 induces hypometabolism in human stem cell-derived neuron and astrocyte networks

Tarczyluk, M. A., Nagel, D. A., Parri, H. R., Tse, E. H. Y., Brown, J. E., Coleman, M. D. & Hill, E. J., 1 Aug 2015, In : Journal of Cerebral Bood Fow and Metabolism. 35, 8, p. 1348-1357 10 p.

Research output: Contribution to journalArticle

Open Access
File
Amyloid
Astrocytes
Alzheimer Disease
Stem Cells
Neurons

A predictive in vitro model of the impact of drugs with anticholinergic properties on human neuronal and astrocytic systems

Woehrling, E. K., Parri, H. R., Tse, E. H. Y., Hill, E. J., Maidment, I. D., Fox, G. C. & Coleman, M. D., 4 Mar 2015, In : PLoS ONE. 10, 3, 18 p., e0118786.

Research output: Contribution to journalArticle

Open Access
File
Cholinergic Antagonists
astrocytes
cholinergic agents
cimetidine
drugs

In vitro protective effect and antioxidant mechanism of Resveratrol induced by Dapsone Hydroxylamine in human cells

Albuquerque, R. V., Malcher, N. S., Amado, L. L., Coleman, M. D., dos Santos, D. C., Borges, R. S., Valente, S. A. S., Valente, V. C. & Chagas Monteiro, M., 18 Aug 2015, In : PLoS ONE. 10, 8, 24 p., e0134768.

Research output: Contribution to journalArticle

Open Access
File
dapsone
resveratrol
protective effect
Antioxidants
Cells
2014

Clinical oxidative stress during leprosy multidrug therapy: impact of dapsone oxidation

Ribeiro Schalcher, T., Borges, R. S., Coleman, M. D., Júnior, J. B., Salgado, C. G., Vieira, J. L. F., Romão, P. R. T., Oliveira, F. R. & Chagas Monteiro, M., 22 Jan 2014, In : PLoS ONE. 9, 1, 9 p., e85712.

Research output: Contribution to journalArticle

Open Access
File
dapsone
leprosy
Dapsone
Oxidative stress
Leprosy

The effects of the fungicides fenhexamid and myclobutanil on SH-SY5Y and U-251 MG human cell lines

Nagel, D. A., Hill, E. J., O'Neil, J., Mireur, A. & Coleman, M. D., Nov 2014, In : Environmental Toxicology and Pharmacology. 38, 3, p. 968-976 9 p.

Research output: Contribution to journalArticle

Fungicides
Pesticides
Cells
Cell Line
Cell Survival
2013
Brain-Derived Neurotrophic Factor
Neurology
Cell culture
Animals
Central Nervous System

Effects of lithium and valproic acid on gene expression and phenotypic markers in an NT2 neurosphere model of neural development

Hill, E., Nagel, D., O'Neil, J., Torr, L., Woehrling, E., Devitt, A. & Coleman, M., 19 Mar 2013, In : PLoS ONE. 8, 3, 9 p., e58822.

Research output: Contribution to journalArticle

Open Access
File
valproic acid
neurodevelopment
lithium
Valproic Acid
Lithium

Functional astrocyte-neuron lactate shuttle in a human stem cell-derived neuronal network

Tarczyluk, M. A., Nagel, D. A., O'Neil, J., Parri, H. R., Tse, E. H. Y., Coleman, M. D. & Hill, E. J., Sep 2013, In : Journal of Cerebral Bood Fow and Metabolism. 33, 9, p. 1386-1393 8 p.

Research output: Contribution to journalArticle

Open Access
File
Astrocytes
Lactic Acid
Stem Cells
Neurons
Coculture Techniques
2012

A preliminary investigation into the impact of a pesticide combination on human neuronal and glial cell lines in vitro

Coleman, M., O'Neil, J., Woehrling, E., Ndunge, O., Hill, E., Menache, A. & Reiss, C., 3 Aug 2012, In : PLoS ONE. 7, 8, 8 p., e42768.

Research output: Contribution to journalArticle

Open Access
File
cyprodinil
Poisons
neuroglia
Pesticides
Neuroglia

Erythrocyte antioxidant protection of rose hips (Rosa spp.)

Widén, C., Ekholm, A., Coleman, M. D., Renvert, S. & Rumpunen, K., 17 Aug 2012, In : Oxidative Medicine and Cellular Longevity. 2012, 8 p., 621579.

Research output: Contribution to journalArticle

Open Access
File
Oxidative stress
Ascorbic Acid
Methanol
Hip
Antioxidants

NT2 derived neuronal and astrocytic network signalling

Hill, E., Jiménez-González, M., Tarczyluk, M., Nagel, D. A., Coleman, M. D. & Parri, R., 2 May 2012, In : PLoS ONE. 7, 5, 10 p., e36098.

Research output: Contribution to journalArticle

Open Access
File
astrocytes
Astrocytes
Neurons
neurons
Calcium

Protection of human erythrocytes against oxidative stress by berries

Widén, C., Coleman, M. D., Renvert, S. & Rumpunen, K., 2012, In : Journal of Berry Research. 2, 3, p. 159-167 9 p.

Research output: Contribution to journalArticle

Vaccinium myrtillus
Oxidative stress
small fruits
Assays
Fruit
2011

Single-cell ELISA and flow cytometry as methods for highlighting potential neuronal and astrocytic toxicant specificity

Woehrling, E., J. Hill, E., Torr, E. E. & Coleman, M., Apr 2011, In : Neurotoxicity Research. 19, 3, p. 472-483 12 p.

Research output: Contribution to journalArticle

Flow cytometry
Glial Fibrillary Acidic Protein
Intermediate Filaments
Flow Cytometry
Cytotoxicity
2010

Dapsone hydroxylamine induces premature removal of human erythrocytes by membrane reorganization and antibody binding

Bordin, L., Fiore, C., Zen, F., Coleman, M. D., Ragazzi, E. & Clari, G., Nov 2010, In : British Journal of Pharmacology. 161, 5, p. 1186-1199 14 p.

Research output: Contribution to journalArticle

Dapsone
Erythrocyte Membrane
Antibodies
Hydroxylamines
Methemoglobinemia

Evaluation of the importance of astrocytes when screening for acute toxicity in neuronal cell systems

Woehrling, E., J. Hill, E. & Coleman, M., Feb 2010, In : Neurotoxicity Research. 17, 2, p. 103-113 11 p.

Research output: Contribution to journalArticle

Astrocytes
Toxicity
Screening
Poisons
Mitochondrial Membrane Potential
2008

A comparison of the apoptotic and cytotoxic effects of hexanedione derivatives on human non-neuronal lines and the neuroblastoma line SH-SY5Y

Coleman, M. D., Zilz, T. R., Griffiths, H. R. & Woehrling, E. K., Jan 2008, In : Basic and Clinical Pharmacology and Toxicology. 102, 1, p. 25-29 5 p.

Research output: Contribution to journalArticle

Neuroblastoma
Isomers
Apoptosis
Derivatives
Flow Cytometry

Dapsone induces oxidative stress and impairs antioxidant defenses in rat liver

Veggi, L. M., Pretto, L., Ochoa, E. J., Catania, V. A., Luquita, M. G., Taborda, D. R., Sánchez Pozzi, E. J., Ikushiro, S., Coleman, M. D., Roma, M. G. & Mottino, A. D., 1 Aug 2008, In : Life Sciences. 83, 5-6, p. 155-163 9 p.

Research output: Contribution to journalArticle

Dapsone
Oxidative stress
Liver
Rats
Oxidative Stress

Differentiating human NT2/D1 neurospheres as a versatile in vitro 3D model system for developmental neurotoxicity testing

Hill, E. J., Woehrling, E. K., Prince, M. & Coleman, M. D., 30 Jul 2008, In : Toxicology. 249, 2-3, p. 243-250 8 p.

Research output: Contribution to journalArticle

Hydroxyurea
Acrylamide
Clone Cells
Neurogenesis
Valproic Acid
Glioma
Toxicity
Interleukin-6
Cells
Cell Line
2007

Apoptotic and necrotic effects of hexanedione derivatives on the human neuroblastoma line SK-N-SH

Zilz, T. R., Griffiths, H. R. & Coleman, M. D., 7 Mar 2007, In : Toxicology. 231, 2-3, p. 210-214 5 p.

Research output: Contribution to journalArticle

Neuroblastoma
Flow cytometry
Cell Cycle
Flow Cytometry
Cells

Assessment of the astrogliotic responses of three human astrocytoma cell lines to ethanol, trimethyltin chloride and acrylamide

Holden, L. J. & Coleman, M. D., 20 Nov 2007, In : Toxicology. 241, 1-2, p. 75-83 9 p.

Research output: Contribution to journalArticle

Acrylamide
Glial Fibrillary Acidic Protein
Astrocytoma
Ethanol
Cells

Common drug interactions

Coleman, M., 2007, In : Syva Drug Monitor.

Research output: Contribution to journalArticle

Conjugative and Transport Mechanisms

Coleman, M., 2007, In : Syva Drug Monitor.

Research output: Contribution to journalArticle

Development of a neurotoxicity test-system, using human post-mitotic, astrocytic and neuronal cell lines in co-culture

Woehrling, E. K., Hill, E. J. & Coleman, M. D., Oct 2007, In : Toxicology in Vitro . 21, 7, p. 1241-1246 6 p.

Research output: Contribution to journalArticle

Coculture Techniques
Cell culture
Astrocytes
Neurons
Cells

Effects of lipoic acid and dihydrolipoic acid on total erythrocytic thiols under conditions of restricted glucose in vitro

Coleman, M. D., Rimmer, G. S. E. & Haenen, G. R. M. M., Feb 2007, In : Basic and Clinical Pharmacology and Toxicology. 100, 2, p. 139-144 6 p.

Research output: Contribution to journalArticle

Thioctic Acid
Sulfhydryl Compounds
Glucose
Methemoglobin
Cells

How drug metabolism influences treatment outcomes

Brown, C. A., Brown, J. Y. & Coleman, M. D., Dec 2007, In : Expert Opinion on Drug Metabolism and Toxicology. 3, 6, p. 913-915 3 p.

Research output: Contribution to journalArticle

Metabolism
Pharmaceutical Preparations
Medicine
Drug interactions
Drug delivery

Improvement of patient tolerance to dapsone: current and future developments

Coleman, M. D., 13 Oct 2007, In : Dermatology Online Journal. 13, 4, 18.

Research output: Contribution to journalArticle

Open Access
2006

Discovery of a potent phenolic N1-benzylidene- pyridinecarboxamidrazone selective against Gram-positive bacteria

Rathbone, D. L., Parker, K. J., Coleman, M. D., Lambert, P. A. & Billington, D. C., 15 Feb 2006, In : Bioorganic and Medicinal Chemistry Letters. 16, 4, p. 879-883 5 p.

Research output: Contribution to journalArticle

Gram-Positive Bacteria
Bacteria
Pharmaceutical Preparations

Effects of glutathione and N-acetyl cysteine on the antimycobacterial efficacy of isoniazid on Mycobacterium fortuitum in vitro

Coleman, M. D., Aerry, R., Wanogho, E., Khan, N. B., Lambert, P. A. & Rathbone, D. L., Dec 2006, In : Journal of Chemotherapy. 18, 6, p. 665-666 2 p.

Research output: Contribution to journalArticle

Effects of lipoic acid and dihydrolipoic acid on 4-aminophenol-mediated erythrocytic toxicity in vitro

Coleman, M. D., Williams, C. & Haenen, G. R. M. M., Sep 2006, In : Basic and Clinical Pharmacology and Toxicology. 99, 3, p. 225-229 5 p.

Research output: Contribution to journalArticle

Thioctic Acid
Toxicity
Sulfhydryl Compounds
Methemoglobin
Dinitrochlorobenzene

Structure and activity in assessing antioxidant activity in vitro and in vivo: a critical appraisal illustrated with the flavonoids

Haenen, G. R. M. M., Arts, M. J. T. J., Bast, A. & Coleman, M. D., Feb 2006, In : Environmental Toxicology and Pharmacology. 21, 2, p. 191-198 8 p.

Research output: Contribution to journalArticle

Flavonoids
Antioxidants
Reaction products
Oxidation
Scavenging

The toxicity of hexanedione isomers in neural and astrocytic cell lines

Woehrling, E. K., Zilz, T. R. & Coleman, M. D., Nov 2006, In : Environmental Toxicology and Pharmacology. 22, 3, p. 249-254 6 p.

Research output: Contribution to journalArticle

Isomers
Toxicity
Cells
Cell Line
Poisons

The use of erythrocytic and animal models in the study of protein phosphorylation

Bordin, L., Coleman, M. D. & Clari, G., Feb 2006, In : Environmental Toxicology and Pharmacology. 21, 2, p. 148-152 5 p.

Research output: Contribution to journalArticle

Phosphorylation
Animals
Animal Models
Proteins
Laboratory Animals
2004
Acetylcysteine
Mononuclear Leukocytes
Thioctic Acid
Cytotoxicity
Cysteine
Dapsone
Methemoglobin
Erythrocytes
Oxidative stress
Oxidative Stress
2003

Aminoglutethimide-induced leucopenia in a mouse model: effects of metabolic and structural determinates

Coleman, M. D., Khalaf, L. F. & Nicholls, P. J., Dec 2003, In : Environmental Toxicology and Pharmacology. 15, 1, p. 27-32 6 p.

Research output: Contribution to journalArticle

Aminoglutethimide
Leukopenia
Platelets
Blood Platelets
Cell Count
Thioctic Acid
Methemoglobin
Vitamin E
Ascorbic Acid
Volunteers
Acetylcysteine
Thioctic Acid
Methemoglobin
Xenobiotics
Cysteine
Quantitative Structure-Activity Relationship
Poisons
Toxicology
Cysteine
Toxicity
Methemoglobin
Xenobiotics
Thyroid Hormones
Oxidants
Erythrocytes
2002

Studies on the toxicity and efficacy of some ester analogues of dapsone in vitro using rat and human tissues

Coleman, M. D., Hadley, S., Perris, A. D., Jorga, K. & Seydel, J. K., 2 Jul 2002, In : Environmental Toxicology and Pharmacology. 12, 1, p. 7-13 7 p.

Research output: Contribution to journalArticle

Dapsone
Toxicity
Rats
Esters
Tissue