20142019

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Personal profile

General

I joined the School of Life & Health Sciences at Aston University in April 2018, having spent the previous two years as a Teaching Fellow in the Department of Biochemical Engineering at UCL. I had a leading role in developing and delivering the Regenerative Medicines Manufacturing Minor and the new undergraduate degree on Medical Sciences and Engineering. Prior to that, I spent 18 months at the University of Bath as a Postdoctoral Researcher in collaboration with Unilever, developing an improved way of predicting how much of a cosmetic or chemical penetrates the skin and reaches the blood stream.

After graduating as a Chemical Engineer at the University of Salamanca (Spain) I moved to Bath to continue my studies and obtained my PhD in Chemical Engineering at the University of Bath in 2015.

Research Interests

My primary research interests can be divided into two main topics, both intimately related to human health: development of tissue-engineered in vitro models of disease, specifically wound infections, and optimisation of bioprocesses for the advance of cellular therapies.

In the first stages of my career I focused on the study of alternatives to typical antibiotics to treat burn wound infections, particularly bacteriophage. My research revolved around the use of engineered materials for controlled release and stabilisation of bacteriophage in order to provide more effective, sustained and lasting treatments. Contemplating the utilisation of tailored synthetic polymeric materials and biomaterials as common ground for my research activities, I moved towards the fields of tissue engineering and bioprocessing. I am particularly interested in artificial vascularisation of tissues and optimisation of bioprocess parameters and methods for the efficient isolation and expansion of cells with regenerative and therapeutic potential, with an emphasis on neuro-regenerative cells and T-cells for immunotherapies.

Additionally, I have an interest in mathematical modelling of biological systems emerging from my engineering background. The applications of differential calculus are practically unlimited since it provides a powerful predictive tool when experimental conditions are difficult to reproduce or even achieve in the first instance.

Qualifications

  • PhD in Chemical Engineering, University of Bath (UK), 2015
  • MSc in Analytical Chemistry, University of Salamanca (Spain), 2011
  • MSc in Biochemical Engineering, University of Salamanca (Spain), 2011

Employment

2018 – date: Lecturer in Regenerative Medicine, School of Life & Health Sciences, Aston University.
2016 – 2018: Teaching Fellow in Regenerative Medicines Manufacturing, Department of Biochemical Engineering, University College London.
2015 – 2016: Postdoctoral Research Assistant, University of Bath.

Membership of Professional Bodies

  • Associate Member of the Institution of Chemical Engineers (AMIChemE).
  • International Society for Viruses of Microorganisms (ISVM).
  • Society of Chemical Industry (SCI).

Contact Details

Phone number    +44 (0) 121 204 4941
Email    p.perez-esteban@aston.ac.uk
Room number    MB433B

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Research Output

Open Access
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  • Bioprocessing strategies to enhance the challenging isolation of neuro-regenerative cells from olfactory mucosa

    Georgiou, M., Reis, J. N. D., Wood, R., Esteban, P. P., Roberton, V., Mason, C., Li, D., Li, Y., Choi, D. & Wall, I., 1 Dec 2018, In : Scientific Reports. 8, 1, 14440.

    Research output: Contribution to journalArticle

    Open Access
    File
  • Prevention of encrustation and blockage of urinary catheters by: Proteus mirabilis via pH-triggered release of bacteriophage

    Milo, S., Hathaway, H., Nzakizwanayo, J., Alves, D. R., Perez Esteban, P., Jones, B. V. & Jenkins, A. T. A., 22 Jun 2017, In : Journal of Materials Chemistry B. 5, 27, p. 5403-5411 9 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • A novel bacteriophage cocktail reduces and disperses Pseudomonas aeruginosa biofilms under static and flow conditions

    Alves, D. R., Perez-Esteban, P., Kot, W., Bean, J. E., Arnot, T., Hansen, L. H., Enright, M. C. & Jenkins, A. T. A., 6 Jan 2016, In : Microbial biotechnology. 9, 1, p. 61-74 14 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • Open Access
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  • Prizes

    SET for BRITAIN Gold award in Engineering

    Patricia Perez Esteban (Recipient), 7 Mar 2016

    Prize: Prize (including medals and awards)

    IChemE Global Awards 2016

    Patricia Perez Esteban (Recipient), 2016

    Prize: Prize (including medals and awards)