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Research Output 2014 2019

  • 7 Article
  • 1 Meeting abstract
  • 1 Review article
2019

Automation in cell and gene therapy manufacturing: from past to future

Moutsatsou, P., Ochs, J., Schmitt, R. H., Hewitt, C. J. & Hanga, M. P., 1 Nov 2019, In : Biotechnology Letters. 41, 11, p. 1245-1253 9 p.

Research output: Contribution to journalReview article

Open Access
File
Gene therapy
Automation
Cell- and Tissue-Based Therapy
Genetic Therapy
Industry
2018

Qualitative and quantitative demonstration of bead-to-bead transfer with bone marrow-derived human mesenchymal stem cells on microcarriers: utilising the phenomenon to improve culture performance

Rafiq, Q. A., Ruck, S., Hanga, M. P., Heathman, T. R. J., Coopman, K., Nienow, A. W., Williams, D. J. & Hewitt, C., 15 Jul 2018, In : Biochemical Engineering Journal. 135, p. 11-21

Research output: Contribution to journalArticle

Open Access
File
Stem cells
Mesenchymal Stromal Cells
Cell culture
Bone
Demonstrations
2017

Dry eye following cataract surgery: The effect of light exposure using an in-vitro model

Ipek, T., Hanga, M. P., Hartwig, A., Wolffsohn, J. & O’donnell, C., 7 Dec 2017, In : Contact Lens and Anterior Eye. 41, 1, p. 128-131

Research output: Contribution to journalArticle

Cataract
Light
Fibroblasts
Cell Survival
In Vitro Techniques

Engineering considerations on the use of liquid/liquid two-phase systems as a cell culture platform

Murasiewicz, H., Nienow, A. W., Hanga, M. P., Coopman, K., Hewitt, C. J. & Pacek, A. W., 7 Jun 2017, In : Journal of Chemical Technology and Biotechnology. 92, 7, p. 1690-1698

Research output: Contribution to journalArticle

Open Access
File
Fluorocarbons
Cell culture
Cell Culture Techniques
engineering
liquid

Expansion of bone marrow-derived human mesenchymal stem/stromal cells (hMSCs) using a two-phase liquid/liquid system

Hanga, M., Murasiewicz, H., Pacek, A. W., Nienow, A. W., Coopman, K. & Hewitt, C., 7 Jun 2017, In : Journal of Chemical Technology and Biotechnology. 92, 7, p. 1577-1589

Research output: Contribution to journalArticle

Open Access
File
Stem cells
Mesenchymal Stromal Cells
bone
Bone
Bone Marrow

Process development of human multipotent stromal cell microcarrier culture using an automated high-throughput microbioreactor

Rafiq, Q. A., Hanga, M. P., Heathman, T. R. J., Coopman, K., Nienow, A. W., Williams, D. J. & Hewitt, C. J., 1 Oct 2017, In : Biotechnology and Bioengineering . 114, 10, p. 2253-2266

Research output: Contribution to journalArticle

Open Access
File
Human Development
Stromal Cells
Cell culture
Cell Culture Techniques
Throughput
2016

Agitation conditions for the culture and detachment of hMSCs from microcarriers in multiple bioreactor platforms

Nienow, A. W., Hewitt, C. J., Heathman, T. R. J., Glyn, V. A. M., Fonte, G. N., Hanga, M. P., Coopman, K. & Rafiq, Q. A., 15 Apr 2016, In : Biochemical Engineering Journal. 108, p. 24-29 6 p.

Research output: Contribution to journalArticle

Open Access
File
Bioreactors
Enzymes
Suspensions
Turbulence
Acoustic waves

Perfluorocarbons: potential for successful expansion of bone marrow-derived human mesenchymal stem cells in a liquid/liquid two phase system

Hanga, M. P., Coopman, K., Nienow, A. W. & Hewitt, C., 6 Jul 2016, In : European Cells and Materials. 32, Suppl.4, p. 30 1 p.

Research output: Contribution to journalMeeting abstract

Open Access
File
2014
Open Access
File
Emulsification
Alginate
Gelation
Membranes
Calcium Carbonate