Personal profile
Biography
I joined Aston University in June 2010 as Lecturer in Pharmacokinetics following over 3 years of extensive pharmacokinetics training with the world-renowned Centre for Applied Pharmacokinetics Research as a post-doctorate research associate, within the School of Pharmacy at the University of Manchester.
I have a broad background and interest in applying the principles of clinical pharmacokinetics to challenging pre-clinical and clinical scenarios in the context of medicines optimisation. As a pharmacokineticist and practicing pharmacist, I have a singular vision of developing tools and approaches which provide clear end-user/clinical benefits. This approach has driven successes in developing research tools to predict oral drug absorption and central nervous system drug biodistribution in addition to medicines optimisation for a range of disease conditions (e.g. tropical disease, cardiovascular disease, drug abuse).
Research Interests
The goal of my research group is to provide guidance in the development, evaluation and implementation of approaches for predicting and improving clinical pharmacokinetics to optimise dosing through medicines optimisation.
Research strands actively pursued within this group are translational and include the techniques of:
- Whole Body Physiologically-Based Pharmacokinetic Modelling
- Population pharmacokinetics
Which are widely applied to a variety of research interests, which include:
- Medicines optimisation
- Deprescribing
- Mental health
- Opioid abuse
- Tropical disease
Collaborative research is welcome and encouraged, please contact me for more details
Teaching Activity
PH1403: Mathematics.
PH2503: Stability kinetics.
PH3603 (module coordinator): Pharmacokinetics, biopharmaceutics.
I am the module coordinator and teach 3rd year MPharm Pharmaceutics module PH3CT1 (Pharmacokinetics, Biopharmaceutics) and MSc. Drug Delivery/Pharmaceutical Sciences module BI4010. I also teach Stability Kinetics (PH2CT2) and mathematics (PH1CT1) throughout the MPharm course.
Qualifications
- MPharm (Masters in Pharmacy) 2(i), School of Pharmacy, University of Manchester, 2001
- PhD (Pharmacology, Molecular Biology and Pharmacokinetics), School of Pharmacy, University of Manchester, 2005
Employment
- 2010-date: Lecturer in Pharmacokinetics, School of Pharmacy, Aston University
- 2005-2009: Post-Doctorate Research Associate (Pharmacokinetics/Pharmacometrics), Centre for Applied Pharmacokinetics Research (CAPKR), School of Pharmacy, University of Manchester, United Kingdom
- 2002-date: Locum pharmacist for national pharmacy chains
- 2001-2002: Pre-registration pharmacist, Superdrug Pharmacy, Wolverhampton, United Kingdom
Membership of Professional Bodies
- Royal Pharmaceutical Society of Great Britain
- International Society for the Study of Xenobiotics
- Academy of Pharmaceutical Sciences Great Britain (APSGB)
- United Kindgom and Ireland Controlled Release Society (UKICRS)
Contact Details
Room: Main Building-434C
Email: [email protected]
Telephone: 0121 204 3288
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Advanced Manufacturing Methods for High-Dose Inhalable Powders
Al-Assaf, H. A., Papadimitriou, S. A., Rahman, A., Badhan, R. & Mohammed, A. R., Mar 2025, In: Pharmaceutics. 17, 3, 23 p., 359.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)30 Downloads (Pure) -
Novel AP39-Loaded Liposomes Sustain the Release of Hydrogen Sulphide, Enhance Blood-Brain Barrier Permeation, and Abrogate Oxidative Stress-Induced Mitochondrial Dysfunction in Brain Cells
Al Tahan, M. A., Marwah, M. K., Dhaliwal, M., Diaz Sanchez, L., Shokr, H., Kaur, M., Ahmad, S., Badhan, R. K., Dias, I. H. & Sanchez-Aranguren, L., 19 Mar 2025, In: Drug Design, Development and Therapy. 19, p. 2067-2079 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Link opens in a new tab Citations (SciVal)27 Downloads (Pure) -
Precision Medicine in Oncology: Imatinib Dosing in the Obese Cancer Population Using Virtual Clinical Trials
Burhanuddin, K., Mohammed, A., Badhan, R. K. S. & Burhanuddin, N. A., Jun 2025, In: CPT: Pharmacometrics & Systems Pharmacology. 14, 6, p. 1050-1064 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)11 Downloads (Pure) -
The Impact of Paediatric Obesity on Drug Pharmacokinetics: A Virtual Clinical Trials Case Study with Amlodipine
Burhanuddin, K., Mohammed, A. & Badhan, R. K. S., 2 Apr 2024, In: Pharmaceutics. 16, 4, 30 p., 489.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)15 Downloads (Pure) -
Precision dosing of venlafaxine during pregnancy: a pharmacokinetics modelling approach
Alenezi, M. & Badhan, R. K. S., 23 Dec 2023, (E-pub ahead of print) In: Journal of Pharmacy and Pharmacology.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Link opens in a new tab Citations (Scopus)18 Downloads (Pure)
Datasets
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Fixed Dose Combination Orally Disintegrating Tablets to Treat Cardiovascular Disease: Formulation, in vitro Characterization and Physiologically Based Pharmacokinetic Modelling to Assess Bioavailability
Dennision, T. (Creator), Smith, J. (Creator), Badhan, R. (Creator) & Mohammed, A.-U.-R. (Creator), Aston Data Explorer, 3 Feb 2017
DOI: 10.17036/researchdata.aston.ac.uk.00000178, https://www.dovepress.com/fixed-dose-combination-orally-disintegrating-tablets-to-treat-cardiova-peer-reviewed-article-DDDT
Dataset