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Research Output

2020

A dynamic perfusion based blood-brain barrier model for cytotoxicity testing and drug permeation

Elbakary, B. & Badhan, R. K. S., 2 Mar 2020, In : Scientific Reports. 10, 1, 3788.

Research output: Contribution to journalArticle

Open Access
File

Drug dosing during pregnancy—opportunities for physiologically based pharmacokinetic models

Abduljalil, K. & Badhan, R. K. S., 1 Aug 2020, In : Journal of Pharmacokinetics and Pharmacodynamics. 47, 4, p. 319-340 22 p.

Research output: Contribution to journalArticle

Quetiapine dose optimisation during gestation: a pharmacokinetic modelling study

Badhan, R. K. S. & Macfarlane, H., 1 May 2020, In : Journal of Pharmacy and Pharmacology. 72, 5, p. 670-681 12 p.

Research output: Contribution to journalArticle

2019
Open Access
File

High-throughput screening of excipients with a biological effect: a kinetic study on the effects of surfactants on efflux-mediated transport

Pollard, J., Rajabi-siahboomi, A., Badhan, R. K. S., Mohammed, A. R. & Perrie, Y., 1 Jun 2019, In : Journal of Pharmacy and Pharmacology. 71, 6, p. 889-897 9 p.

Research output: Contribution to journalArticle

Open Access
File

Intracellular uptake of EGCG-loaded deformable controlled release liposomes for skin cancer

Marwah, M., Perrie, Y., Badhan, R. K. S. & Lowry, D., 9 May 2019, In : Journal of Liposome Research. 14 p.

Research output: Contribution to journalArticle

Open Access
File

The optimization of methadone dosing whilst treating with rifampicin: A pharmacokinetic modeling study

Badhan, R. K. S., Gittins, R. & Al Zabit, D., 1 Jul 2019, In : Drug and Alcohol Dependence. 200, p. 168-180 13 p.

Research output: Contribution to journalArticle

Open Access
File
2018

Clopidogrel Pharmacokinetics in Malaysian Population Groups: The Impact of Inter-Ethnic Variability

Zakaria, Z., Fong, A. & Badhan, R., 26 Jul 2018, In : Pharmaceuticals. 11, 3, 74.

Research output: Contribution to journalArticle

Open Access
File
Open Access
File
Open Access
File
Open Access
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2017

Application of pharmacokinetics modelling to predict human exposure of a cationic liposomal subunit antigen vaccine system

Badhan, R. K. S., Khadke, S. & Perrie, Y., 7 Dec 2017, In : Pharmaceutics. 9, 4, 57.

Research output: Contribution to journalArticle

Open Access
File
Open Access
File
Open Access
File
Open Access
File
Open Access
File
2016

Design of experiments to study the impact of process parameters on droplet size and development of non-invasive imaging techniques in tablet coating

Dennison, T. J., Smith, J., Hofmann, M. P., Bland, C. E., Badhan, R. K., Al-Khattawi, A. & Mohammed, A. R., 22 Aug 2016, In : PLoS ONE. 11, 8, 17 p., e0157267.

Research output: Contribution to journalArticle

Open Access
File

Development and evaluation of a novel intranasal spray for the delivery of amantadine

Lungare, S., Bowen, J. & Badhan, R., Mar 2016, In : Journal of Pharmaceutical Sciences. 105, 3, p. 1209-1220 12 p.

Research output: Contribution to journalArticle

Open Access
File

Phytochemical-loaded mesoporous silica nanoparticles for nose-to-brain olfactory drug delivery

Lungare, S., Hallam, K. & Badhan, R. K. S., 20 Nov 2016, In : International Journal of Pharmaceutics. 513, 1-2, p. 280-293 14 p.

Research output: Contribution to journalArticle

Open Access
File
2015

Physiologically based pharmacokinetic modelling in drug delivery

Badhan, R. K. S., 29 Jun 2015, Computational pharmaceutics: application of molecular modeling in drug delivery. Ouyang, D. & Smith, S. C. (eds.). Wiley, p. 263-291 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access
File
2014

Development of a physiologically-based pharmacokinetic model of the rat central nervous system

Badhan, R. K. S., Chenel, M. & Penny, J. I., 18 Mar 2014, In : Pharmaceutics. 6, 1, p. 97-136 40 p.

Research output: Contribution to journalArticle

Open Access
File

Improving brain drug targeting through exploitation of the nose-to-brain route: a physiological and pharmacokinetic perspective

Badhan, R. K. S., Kaur, M., Lungare, S. & Obuobi, S., 30 Jun 2014, In : Current Drug Delivery. 11, 4, p. 458-471 14 p.

Research output: Contribution to journalArticle

2012

The impact of ageing on the barriers to drug delivery

Perrie, Y., Singh Badhan, R., Kirby, D. J., Lowry, D., Mohammed, A-U-R. & Ouyang, D., 20 Jul 2012, In : Journal of Controlled Release. 161, 2, p. 389-398 10 p.

Research output: Contribution to journalArticle

2009

Identification of putative steroid-binding sites in human ABCB1 and ABCG2

Mares-Sámano, S., Badhan, R. & Penny, J., Sep 2009, In : European Journal of Medicinal Chemistry. 44, 9, p. 3601-3611 11 p.

Research output: Contribution to journalArticle

Methodology for development of a physiological model incorporating CYP3A and P-glycoprotein for the prediction of intestinal drug absorption

Badhan, R., Penny, J., Galetin, A. & Houston, J. B., Jun 2009, In : Journal of Pharmaceutical Sciences. 98, 6, p. 2180-2197 18 p.

Research output: Contribution to journalArticle

2006

In silico modelling of the interaction of flavonoids with human P-glycoprotein nucleotide-binding domain

Badhan, R. & Penny, J., Mar 2006, In : European Journal of Medicinal Chemistry. 41, 3, p. 285-295 11 p.

Research output: Contribution to journalArticle