Personal profile
Research Interests
In recent years it has become clear that in addition to their traditional roles as “housekeepers” of the brain’s environment, astrocytes can also signal to neurones using many of the mechanisms previously thought exclusive to neuronal transmission. The release of such transmitters as glutamate and ATP can elicit and affect neuronal excitability and modulate synaptic transmission.
The focus of my research group is on the mechanisms of astrocyte-neuron signalling in the thalamus, and how such signalling is involved in thalamic function. The techniques used are combined electrophysiological recording and Calcium imaging.
Teaching Activity
PH1401 (Module coordinator): Neuronal excitability, cardiovascular physiology, endocrinology, brain anatomy, respiration and blood pressure practical classes.
PH2509: Anaemia, haemostasis, inotropy, vasodilators.
Pharmacy Programme First year Tutor
Member of the Neurophysiology & Clinical Neuroimaging Research Group
Employment
- 2021 - Professor in Pharmacology, Aston University
- 2019 - Reader in Pharmacology , Aston University
- 2009- Senior Lecturer in Pharmacology, Aston University.
- 2004- Lecturer in Pharmacology, Aston University.
- 1995-2004 School of Biosciences, Cardiff University.
- 1992-1995 Department of Pharmacology, University of California at San Francisco.
- 1988-1992 Department of Neurophysiology, Southampton University.
Contact Details
Email: [email protected]
Telephone: +44 (0) 121 204 4049
Fax: +44 (0) 121 359 0733
Education/Academic qualification
PhD, Studies on Chloride in the somatic muscle bag cells of the parasitic nematode Ascaris Suum, University of Southampton
1 Oct 1988 → 1 Oct 1991
Award Date: 2 Dec 1991
BSc, Physiology with Pharmacology, University of Southampton
1 Oct 1985 → 31 Jul 1988
Award Date: 14 Jul 1988
Keywords
- QP Physiology
- glial cells
- astrocytes
- electrophysiology
- calcium imaging
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Altered metabolic function induced by Aβ‐oligomers and PSEN1 mutations in iPSC ‐derived astrocytes
Elsworthy, R. J., Finelli, M. J., Aqattan, S., Dunleavy, C., King, M., Ludlam, A., Tarczyluk, M. A., Allen, S. L., Prosser, S., Chen, R., Jarquin, S. M., Kim, D. H., Brown, J., Aldred, S., Parri, H. R. & Hill, E. J., Jan 2025, In: Journal of Neurochemistry. 169, 1, 20 p., e16267.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Downloads (Pure) -
Inferring structure of cortical neuronal networks from activity data: A statistical physics approach
Po, H. F., Houben, A. M., Haeb, A.-C., Jenkins, D. R., Hill, E. J., Parri, H. R., Soriano, J. & Saad, D., Jan 2025, In: PNAS Nexus. 4, 1, 13 p., pgae565.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (SciVal)14 Downloads (Pure) -
Photoactivated Adenylyl Cyclase in Cortical Astrocytes Promotes Synaptic Potentiation and Reveals Alterations in Huntington’s Disease
Sitjà-Roqueta, L., Ngum, N. M., Zherebstov, E., Küçükerden, M., Givehchi, M., Bova, V., Delicata, F., Anaya-Cubero, E., Santamaria, E., Fernández-Irigoyen, J., Conde-Berriozabal, S., Castañé, A., Sokolovski, S., Rafailov, E., Rodríguez, M. J., Alberch, J., Dalkara, D., Möglich, A., Bykov, A. & Meglinski, I. & 2 others, , 21 Nov 2025, In: iScience. 28, 11, 23 p., 113640.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure) -
Utilizing cues from developmental neurogenesis and gliogenesis for better in vitro brain models
Gallagher, M. L., Parri, H. R., Ross, E. & Hill, E. J., 31 Dec 2025, In: Artificial Cells, Nanomedicine, and Biotechnology. 53, 1, p. 440-452 13 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2 Downloads (Pure) -
Non-Invasive Near-Infrared Optogenetics: Aspirational Dream or Approaching Feasibility
Galiakhmetova, D., Dremin, V., Koviarov, A., Stoliarov, D., Ngum, N., Parri, H. R., Gorodetsky, A., Maimaris, M., Shcherbakova, D. M., Baloban, M., Verkhusha, V. V., Sokolovski, S. G. & Rafailov, E. U., 20 Jun 2024, Neurophotonics II. Cizmar, T. & Fellin, T. (eds.). Society of Photo-Optical Instrumentation Engineers (SPIE), 4 p. 1300703. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 13007).Research output: Chapter in Book/Published conference output › Conference publication
Datasets
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Research Data - Inferring Structure of Cortical Neuronal Networks from Firing Data: A Statistical Physics Approach
Po, H. F. (Creator), Houben, A. M. (Creator), Haeb, A.-C. (Creator), Jenkins, D. R. (Creator), Hill, E. J. (Creator), Parri, R. (Creator), Soriano, J. (Creator) & Saad, D. (Creator), Aston Data Explorer, 11 Apr 2024
DOI: 10.17036/researchdata.aston.ac.uk.00000635
Dataset
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PLoS ONE (Journal)
Parri, R. (Peer reviewer)
May 2012Activity: Peer-review and editorial work types › Publication peer-review
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Frontiers in Cellular Neuroscience (Journal)
Parri, R. (Peer reviewer)
May 2012Activity: Peer-review and editorial work types › Publication peer-review
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Chinese Journal of Physiology (Journal)
Parri, R. (Peer reviewer)
Apr 2012Activity: Peer-review and editorial work types › Publication peer-review
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Epilepsy Research UK International Expert Workshop
Parri, R. (Participant)
15 Mar 2012Activity: Participating in or organising an event types › Participation in conference
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Frontiers in Neuropharmacology (Journal)
Parri, R. (Peer reviewer)
Mar 2012Activity: Peer-review and editorial work types › Publication peer-review