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Research Output 1995 2017

Article
Open Access
File
Fibroblasts
Cell Movement
Conformations
Enzymes
Extracellular Matrix

A spirochete isolated from a case of severe virulent ovine foot disease is closely related to a Treponeme isolated from human periodontitis and bovine digital dermatitis

Collighan, R., Naylor, R. D., Martin, P. K., Cooley, B. A., Buller, N. & Woodward, M. J., 1 Jun 2000, In : Veterinary Microbiology. 74, 3, p. 249-57 9 p.

Research output: Contribution to journalArticle

Digital Dermatitis
Foot Diseases
Sheep Diseases
foot diseases
Spirochaetales

Assessment of cell viability in a three-dimensional enzymatically cross-linked collagen scaffold

Garcia, Y., Collighan, R., Griffin, M. & Pandit, A. S., Oct 2007, In : Journal of Materials Science : Materials in Medicine. 18, 10, p. 1991-2001 11 p.

Research output: Contribution to journalArticle

Scaffolds (biology)
Collagen
Scaffolds
Cell Survival
Cells

Celiac disease IgA modulates vascular permeability in vitro through the activity of transglutaminase 2 and RhoA

Myrsky, E., Caja, S., Simon-Vecsei, Z., Korponay-Szabo, I. R., Nadalutti, C., Collighan, R., Mongeot, A., Griffin, M., Mäki, M., Kaukinen, K. & Lindfors, K., Oct 2009, In : Cellular and Molecular Life Sciences. 66, 20, p. 3375-85 11 p.

Research output: Contribution to journalArticle

Capillary Permeability
Celiac Disease
Autoantibodies
Immunoglobulin A
Endothelium

Characterization of a microbial transglutaminase cross-linked type II collagen scaffold

O Halloran, D. M., Collighan, R., Griffin, M. & Pandit, A. S., 17 Jul 2006, In : Tissue Engineering. 12, 6, p. 1467-1474 8 p.

Research output: Contribution to journalArticle

Transglutaminases
Collagen Type II
Scaffolds
Scaffolds (biology)
Covalent bonds
Open Access
File
Cell signaling
Heparitin Sulfate
Heparin
Binding Sites
Extracellular Matrix
Aeromonas salmonicida
outer membrane proteins
molecular cloning
iron
membrane

Cross-linking of collagen I by tissue transglutaminase provides a promising biomaterial for promoting bone healing

Fortunati, D., Chau, D. Y. S., Wang, Z., Collighan, R. J. & Griffin, M., 31 Jul 2014, In : Amino Acids. 46, 7, p. 1751-1761 11 p.

Research output: Contribution to journalArticle

Biocompatible Materials
Bone
Collagen
Bone and Bones
Osteoblasts

Enzymatic stabilization of gelatin-based scaffolds

Broderick, E. P., O'Halloran, D. M., Rochev, Y. A., Griffin, M., Collighan, R. & Pandit, A. S., 15 Jan 2005, In : Journal of biomedical materials research: part B. 72, 1, p. 37-42 6 p.

Research output: Contribution to journalArticle

Transglutaminases
Gelatin
Scaffolds
Gels
Stabilization

Epithelial transport and deamidation of gliadin peptides: a role for coeliac disease patient immunoglobulin A

Rauhavirta, T., Qiao, S-W., Jiang, Z., Myrsky, E., Loponen, J., Korponay-Szabó, I. R., Salovaara, H., Garcia-Horsman, J. A., Venäläinen, J., Männistö, P. T., Collighan, R., Mongeot, A., Griffin, M., Mäki, M., Kaukinen, K. & Lindfors, K., Apr 2011, In : Clinical and Experimental Immunology. 164, 1, p. 127-136 10 p.

Research output: Contribution to journalArticle

Open Access
Gliadin
Celiac Disease
Abdomen
Immunoglobulin A
Peptides

Glycogen, the preferred energy source for extracellular protein formation and growth of Aeromonas salmonicida

Coleman, G., Collighan, R. & Dodsworth, S., May 1995, In : Journal of Fish Diseases. 18, 3, p. 221-228 8 p.

Research output: Contribution to journalArticle

Aeromonas salmonicida
Glycogen
Maltose
glycogen
maltose
Factor XIIIa
Transglutaminases
Blood Coagulation Factors
Water
Scaffolds
File
NF-kappa B
Transforming Growth Factors
Transforming Growth Factor beta
Nitric Oxide
Fibroblasts
Indwelling Catheters
Catheters
Central Venous Catheters
Equipment and Supplies
Factor XIIIa

Inhibition of transglutaminase 2 enzymatic activity ameliorates the anti-angiogenic effects of coeliac disease autoantibodies

Caja, S., Myrsky, E., Korponay-Szabo, I. R., Nadalutti, C., Sulic, A-M., Lavric, M., Sblattero, D., Marzari, R., Collighan, R., Mongeot, A., Griffin, M., Mäki, M., Kaukinen, K. & Lindfors, K., Apr 2010, In : Scandinavian Journal of Gastroenterology. 45, 4, p. 421-427 7 p.

Research output: Contribution to journalArticle

Celiac Disease
Autoantibodies
Abdomen
Endothelial Cells
Genetic Recombination

Inhibition of transglutaminase activity reduces extracellular matrix accumulation induced by high glucose levels in proximal tubular epithelial cells

Skill, N. J., Johnson, T. S., Coutts, I. G. . C., Saint, R. E., Fisher, M., Huang, L., El Nahas, A. M., Collighan, R. & Griffin, M., 12 Nov 2004, In : Journal of Biological Chemistry. 279, 46, p. 47754-47762 9 p.

Research output: Contribution to journalArticle

Open Access
File
Transglutaminases
Extracellular Matrix
Epithelial Cells
Glucose
Collagen

In vitro characterization of a collagen scaffold enzymatically cross-linked with a tailored elastin-like polymer

Garcia, Y., Hemantkumar, N., Collighan, R., Griffin, M., Rodriguez-Cabello, J. C. & Pandit, A., 10 Jul 2009, In : Tissue Engineering: Parts A, B and C. 15, 4, p. 887-899 13 p.

Research output: Contribution to journalArticle

Elastin
Scaffolds (biology)
Collagen
Scaffolds
Polymers

In vivo effects of tailored laminin-332 α3 conjugated scaffolds enhances wound healing: a histomorphometric analysis

Damodaran, G., Tiong, W. H. C., Collighan, R., Navsaria, H., Griffin, M. & Pandit, A., 5 Mar 2013, In : Journal of Biomedical Materials Research: Part A. 101, 10, p. 2788-2795 8 p.

Research output: Contribution to journalArticle

Transglutaminases
Scaffolds
Peptides
Scaffolds (biology)
Cell adhesion

Isopeptidase activity of human transglutaminase 2: disconnection from transamidation and characterization by kinetic parameters

Kiraly, R., Thangaraju, K., Nagy, Z., Collighan, R., Nemes, Z., Griffin, M. & Fésüs, L., Jan 2016, In : Amino Acids. 48, 1, p. 31-40 10 p.

Research output: Contribution to journalArticle

Open Access
File
Kinetic parameters
Human Activities
Mutation
Amines
Physiological Phenomena

New 6-ethoxyquinolines as simple optoquine analogues

Jones, R. C. F., Collighan, R., Crane, J., Hodges, N. J., Ling, M. S. & Stroud, J., 2002, In : Synthetic communications. 32, 20, p. 3185-3191 7 p.

Research output: Contribution to journalArticle

Derivatives
4-methylquinoline
ethylhydrocupreine

Non-curliation of Escherichia coli O78:K80 isolates associated with IS1 insertion in csgB and reduced persistence in poultry infection

La Ragione, R. M., Collighan, R. & Woodward, M. J., Jun 1999, In : FEMS Microbiology Letters. 175, 2, p. 247-253 7 p.

Research output: Contribution to journalArticle

Poultry
Escherichia coli
Infection
Genes
Culture Techniques

Novel approach to improving enzyme penetration

Senior, K., Griffin, M. & Collighan, R., Jan 2003, British Leather Technology Centre journal, 46.

Research output: Contribution to specialist publicationArticle

Porphyromonas gingivalis gingipains cause defective macrophage migration towards apoptotic cells and inhibit phagocytosis of primary apoptotic neutrophils: gingipains, apoptotic cell removal & inflammation

Castro, S. A., Collighan, R., Lambert, P. A., Dias, H. H. K., Chauhan, P., Bland, C. E., Milic, I., Millward, M. R., Cooper, P. R. & Devitt, A., 2 Mar 2017, In : Cell Death and Disease. 8, 3, 8 p., e2644.

Research output: Contribution to journalArticle

Open Access
File
Cytophagocytosis
Porphyromonas gingivalis
Neutrophils
Macrophages
Inflammation

Recent advances in the development of tissue transglutaminase (TG2) inhibitors

Badarau, E., Collighan, R. J. & Griffin, M., Jan 2013, In : Amino Acids. 44, 1, p. 119-127 9 p.

Research output: Contribution to journalArticle

Open Access
File
Biological Phenomena
Transglutaminases
Enzyme Activation
Huntington Disease
Celiac Disease
Open Access
File
Syndecan-2
Syndecan-4
Cell adhesion
Fibronectins
Cell Adhesion

Sequence analysis and distribution in Salmonella enterica serovars of IS3-like elements

Collighan, R., Walker, S. L. & Woodward, M. J., 2000, In : International Journal of Medical Microbiology. 290, 7, p. 619-26 8 p.

Research output: Contribution to journalArticle

Salmonella enterica
Sequence Analysis
Bacteriophage P22
Genome
Operon

Sequence analysis and distribution of an IS3-like insertion element isolated from Salmonella enteritidis

Collighan, R. & Woodward, M. J., 1997, In : FEMS Microbiology Letters. 154, 2, p. 207-213 7 p.

Research output: Contribution to journalArticle

Salmonella enteritidis
Insertional Mutagenesis
Operon
Salmonella
Sequence Analysis

Spirochaetes and other bacterial species associated with bovine digital dermatitis

Collighan, R. & Woodward, M. J., Nov 1997, In : FEMS Microbiology Letters. 156, 1, p. 37-41 5 p.

Research output: Contribution to journalArticle

Digital Dermatitis
Spirochaetales
Treponema denticola
rRNA Genes
Polymerase Chain Reaction

Synthesis of potent water-soluble tissue transglutaminase inhibitors

Griffin, M., Mongeot, A., Collighan, R., Saint, R. E., Jones, R. A., Coutts, I. G. C. & Rathbone, D. L., 15 Oct 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 20, p. 5559-5562 4 p.

Research output: Contribution to journalArticle

Diazooxonorleucine
Lead compounds
Transglutaminases
Dipeptides
Water

Tailored laminin-332 alpha3 sequence is tethered through an enzymatic linker to a collagen scaffold to promote cellular adhesion

Damodaran, G., Collighan, R., Griffin, M., Navsaria, H. & Pandit, A. S., Sep 2009, In : Acta Biomaterialia. 5, 7, p. 2441-2450 10 p.

Research output: Contribution to journalArticle

Transglutaminases
Scaffolds (biology)
Collagen
Scaffolds
Peptides
Transglutaminases
Liposomes
Liver Cirrhosis
Liver
Fibrosis

Tethering a laminin peptide to a crosslinked collagen scaffold for biofunctionality

Damodaran, G., Collighan, R., Griffin, M. & Pandit, A., 15 Jun 2009, In : Journal of Biomedical Materials Research: Part A. 89A, 4, p. 1001-1010 10 p.

Research output: Contribution to journalArticle

Laminin
Scaffolds (biology)
Transglutaminases
Collagen
Peptides

The biotechnological applications of transglutaminases

Collighan, R., Cortez, J. & Griffin, M., Jun 2002, In : Minerva Biotecnologica. 14, 2, p. 143-148 6 p.

Research output: Contribution to journalArticle

Transglutaminases
Enzymes
Biocatalysts
Cosmetics
Textile industry

The cellular response to transglutaminase-cross-linked collagen

Chau, D. Y. S., Collighan, R., Verderio, E. A. M., Addy, V. L. & Griffin, M., Nov 2005, In : Biomaterials. 26, 33, p. 6518-6529 12 p.

Research output: Contribution to journalArticle

Transglutaminases
Collagen
Osteoblasts
Collagen Type I
Foreskin

Thermodynamics of binding of regulatory ligands to tissue transglutaminase

Bergamini, C. M., Dondi, A., Lanzara, V., Squerzanti, M., Cervellati, C., Montin, K., Mischiati, C., Tasco, G., Collighan, R., Griffin, M. & Casadio, R., 22 Dec 2009, In : Amino Acids. 39, 1, p. 297-304 8 p.

Research output: Contribution to journalArticle

Thermodynamics
Guanosine Triphosphate
Ligands
Calcium
Hot Temperature

The role of tissue transglutaminase (TG2) in regulating the tumour progression of the mouse colon carcinoma CT26

Kotsakis, P., Wang, Z., Collighan, R. J. & Griffin, M., Oct 2011, In : Amino Acids. 41, 4, p. 909-921 13 p.

Research output: Contribution to journalArticle

Open Access
File
Fibronectins
Integrins
Tumors
Colon
Carcinoma

The SEF14 fimbrial antigen of Salmonella enterica serovar Enteritidis is encoded within a pathogenicity islet

Collighan, R. & Woodward, M. J., Jun 2001, In : Veterinary Microbiology. 80, 3, p. 235-245 11 p.

Research output: Contribution to journalArticle

pathogenicity islands
Genomic Islands
Salmonella enteritidis
Salmonella Enteritidis
plasmids
Salmonella enteritidis
Virulence
Alleles
Phenotype
Frameshift Mutation

The visualisation of vitreous using surface modified poly(lactic-co-glycolic acid) microparticles

Chau, D. Y. S., Tint, N. L., Collighan, R. J., Griffin, M., Dua, H. S., Shakesheff, K. M. & Rose, F. R. A. J., 2010, In : British Journal of Ophthalmology. 94, 5, p. 648-653 6 p.

Research output: Contribution to journalArticle

Open Access
File
Triamcinolone
Suspensions
Transglutaminases
Vitrectomy
Swine

Towards development of a dermal rudiment for enhanced wound healing response

Garcia, Y., Wilkins, B., Collighan, R., Griffin, M. & Pandit, A. S., Mar 2008, In : Biomaterials. 29, 7, p. 857-868 12 p.

Research output: Contribution to journalArticle

Collagen
Scaffolds
Wound Healing
Re-Epithelialization
Transglutaminases

Transglutaminase 2 cross-linking of matrix proteins: biological significance and medical applications

Collighan, R. & Griffin, M., Apr 2009, In : Amino Acids. 36, 4, p. 659-670 12 p.

Research output: Contribution to journalArticle

Medical applications
Transglutaminases
Cell adhesion
Biocompatible Materials
Pathology

Transglutaminases as tanning agents for the leather industry

Collighan, R., Clara, S., Li, X., Parry, J. & Griffin, M., Jul 2004, In : Journal of the American Leather Chemists Association. 99, 7, p. 293-302 10 p.

Research output: Contribution to journalArticle

Tanning
Transglutaminases
Leather
Crosslinking
Collagen

Transglutaminases in the leather industry

Collighan, R. & Griffin, M., Jan 2003, British Leather Technology Centre journal, 46.

Research output: Contribution to specialist publicationArticle

Chapter

Collagen: structure and modification for biomedical applications

Chau, D., Collighan, R. & Griffin, M., 12 Sep 2007, Trends in Biomaterials Research. Pannone, P. J. (ed.). New York (US): Nova science, p. 143-190 48 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles

Bergamini, C. M., Collighan, R. J., Wang, Z. & Griffin, M., 16 Dec 2011, Advances in enzymology: and related areas of molecular biology. Toone, E. J. (ed.). Hoboken, NJ (US): Wiley, Vol. 78. p. 1-46 46 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

transglutaminase 2
Conference contribution

In-vitro characterization of an enzymatically cross-linked collagen-elastin like polymer scaffold

Garcia, Y., Naik, H., Collighan, R., Griffin, M., Rodriguez Cabello, J. C. & Pandit, A., 1 Dec 2008, 8th World Biomaterials Congress 2008. Vol. 2.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Meeting abstract

Scaffold characterisation for nucleus pulposus regeneration

Halloran, D. O., White, M., Collighan, R., Griffin, M. & Pandit, A., 1 Jul 2005, In : European Cells and Materials. 10, SUPPL.3, p. 9 1 p.

Research output: Contribution to journalMeeting abstract

Patent

Novel Polypeptides and Use Thereof

Collighan, R., Griffin, M., Pytel, K. & Wang, Z., 28 Apr 2011, IPC No. A61K38/04, Patent No. GB 1107147.9

Research output: Patent

Open Access
Heparin
Binding Sites
Peptides
Syndecan-4
Antibodies