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    • Aston Triangle

      B4 7ET Birmingham

      United Kingdom

    • School of Life & Health Sciences, Aston University, Aston Triangle

      B4 7ET Birmingham

      United Kingdom

    Accepting PhD Students

    Personal profile

    Biography

    Zaki is an Honorary Consultant Endocrinologist at University Hospitals Birmingham (UHB) NHS Foundation Trust. At Aston, he is a Clinical Associate Professor and the Founding Director of the Integrated Clinical Academic Training Programme, having led successful NIHR bids to fund Academic Clinical Fellows (24 new posts to date). Through these initiatives, Aston has become recognised as a regional hub for clinical academic career development (in medicine), working in partnership with Midlands medical schools including Birmingham, Warwick, and Keele. 

    He was Visiting Professor in Health and Life Sciences at Coventry University between 2017 and 2020. As a consultant he was awarded a Research Scholarship by the NIHR WM Clinical Research Network. He trained in London and Birmingham on a clinical academic track and held NIHR and European Research Council funded fellowships, completing a PhD at the University of Birmingham followed by a Clinical Lecturer post. 

    His portfolio spans metabolic bone and parathyroid disorders, academic training leadership and medical education research, bridging clinical medicine, translational research and educational innovation, with a focus on developing equitable, inclusive and engaging learning environments for future doctors and those in training. 

    He leads specialist endocrine services at UHB with specialist interests in  Metabolic and Rare Bone Disease, Young Adult/Transitional Care, General Endocrinology and Internal Medicine.

    He has held external roles at other Medical Schools, Post-graduate Colleges and Professional Bodies in the UK and internationally. He is a Clinical Advisor for the Royal Osteoporosis Society (ROS) and sits on the Society for Endocrinology (SfE) Corporate Liaison Committee. He sits on the steering committee of the SfE Hypoparathyroidism Registry, and is an author of their expert consensus on the Management of Endocrine Conditions at the End of Life.  He is a former Editor of Osteoporosis Review, and served terms on the ROS Clinical Research Committee, the SfE Public Engagement Committee and as a Editorial Advisor for the British Medical Journal. He is the QS World Ranking Champion for Aston Medical School. 

    He contributed to the European Society for Endocrinology's Consensus Committee on Parathyroid disease (PARAT), and the International Taskforce on Parathyroid disease as well as participating in Delphi processes on use of biomarkers for ageing research, and Relative Energy Deficiency in Dance (RED-D). He was a co-investigator on the TOPaZ Study, the largest Randomised Trial in patients with Osteogenesis Imperfecta. 

    He has published extensively including in high impact journals such as New England Journal of Medicine, the Lancet, PNAS, JCI, Lancet Diabetes and Endocrinology and the Journal of Clinical Endocrinology and Metabolism. 

    He supervises PhD and MD students and NIHR Academic Clinical Fellows.

    He is passionate about Medical Education, and continuous professional development - in 2025 he achieved a distinction in his MSc in Medical Education at Oxford University. He is lead for stage 5 of the MBChB Programme at Aston, and previously led year 3 of the course. His educational leadership emphasises active clinical reasoning and inclusivity in clinical training. 

    Professional/editorial offices

    • Clinical Advisor to the Royal Osteoporosis Society
    • Member of the Society for Endocrinology Corporate Liaison Committee. 
    • Media Ambassador for Society for Endocrinology
    • Member of Steering Committee of SfE Hypoparathyroidism Registry
    • Co-Author of SfE Expert Consensus Statement on Management of Endocrine Conditions at the End of Life
    • Advisory Board Member/ Consultant to Pharmaceutical Industry partners
    • QS World Ranking Champion at Aston Medical School
    • Former Editor of Osteoporosis Review (the journal of the Royal Osteoporosis Society)
    • Former Member of Royal Osteoporosis Society Clinical and Research Committee
    • Former Society for Endocrinology Public Engagement Committee Member
    • Former Editorial Advisor for theBMJ

     

    Research Interests

    • Parathyroid disease
    • Endocrine determinants of adverse ageing (including sarcopenia and frailty)
    • Musculoskeletal Endocrinology
    • Metabolic/rare bone diseases
    • Medical Education Research: Widening Participation in Medical Education, Clinical Reasoning/ diagnostic decision making
    • Digital Health

    Employment

    • Clinical Associate Professor at Aston Medical School
    • Consultant Endocrinologist at Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust
    • Honorary Clinical Associate Professor in Department for Metabolism and Systems Research (IMSR) at University of Birmingham
    • Previous Visiting Professorship in Health and Life Sciences at Coventry University
    • Previous roles as Clinical Lecturer, European Research Council Funded Clinical Research Fellow and NIHR Academic Clinical Fellow at University of Birmingham
    • Previous Specialty Training in Endocrinology, Diabetes and General Internal Medicine in West Midlands Deanery 
    • Previous Senior House Officer Training on St Bartholomew's and Royal London Hospitals Training Scheme

    Qualifications

    • Master of Science (MSc) in Medical Education (distinction) - University of Oxford
    • Fellowship of Royal College of Physicians
    • Senior Fellowship of Advance HE (SFHEA)
    • PhD (Medicine) University of Birmingham
    • Completion of Specialist Training in Endocrinology and Diabetes and General Internal Medicine (UK CCT)
    • Specialty Certificate in Diabetes & Endocrinology - MRCP(Diabetes and Endocrinology)
    • Membership of Royal College of Physicians (MRCP(UK))
    • Post-graduate Certificate in Teaching and Learning in Higher Education (distinction) (Aston University)
    • Post-graduate award in Medical Education (Warwick University)
    • Bachelor in Medicine and Surgery (MBBS)(Barts and the London, Queen Mary University of London)
    • Bachelor of Medical Sciences Honours (BMedSci(Hons)(intercalated degree at Bart's and the London, QMUL)

    Membership of Professional Bodies

    • Fellowship of Royal College of Physicians
    • Senior Fellowship of Advance HE
    • Member of Society for Endocrinology
    • Member of the European Society for Endocrinology
    • Member of the Royal Osteoporosis Society

    Teaching Activity

    • MBChB (Medicine) Year 5 Lead
    • Director of Integrated Clinical Academic Training Programme (Aston)
    • MBChB Leadership roles in Clinical Reasoning and Endocrinology. 
    • Previously MBChB Year 3 Lead and Year Assessment Lead
    • Queen Elizabeth Hospital Birmingham Lead for Endocrinology Placements
    • External Examiner with Sunderland Medical School
    • PhD Supervisor for UoB/UHB Clinical Research Fellow (Acute Sarcopenia)
    • MD Supervisor for Project on Digital Health Approaches to Sarcopenia in Inflammatory Bowel Disease (Aston - partnership with SWBH and Royal Wolverhampton NHS Trusts)
    • Supervisor for NIHR ACF projects on Parathyroid disease
    • Acted as External PhD Examiner

    External positions

    Consultant Endocrinologist, University Hospitals Birmingham , Birmingham , UK.

    1 Aug 2016 → …

    Expertise related to UN Sustainable Development Goals

    In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

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    Collaborations and top research areas from the last five years

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    • Resting energy expenditure in professional dancers as an objective measure of low energy expenditure

      Wyon, M., Allen, N., Brown-Appenzeller, D., Cloak, R., Devonport, T., Gregory, K., Penner, J., Hassan-Smith, Z., Webster, R. & Wolman, R., 2 Apr 2026, In: BMJ Open Sport & Exercise Medicine. 12, 2, 9 p., e003216.

      Research output: Contribution to journalArticlepeer-review

      Open Access
      File
    • Adolescent and Young Adult Bone Health

      Alhamamy, N., Gittoes, N., Crabtree, N. & Hassan Smith, Z., 16 Apr 2025, Adolescent and Young Adult Rheumatology In Clinical Practice. p. 241-253 (In Clinical Practice (ICP)).

      Research output: Chapter in Book/Published conference outputChapter (peer-reviewed)peer-review

    • An Expert Consensus Statement on Biomarkers of Aging for Use in Intervention Studies

      Perri, G., French, C., Agostinis-Sobrinho, C., Anand, A., Antarianto, R. D., Arai, Y., Baur, J. A., Cauli, O., Clivaz-Duc, M., Colloca, G., Demetriades, C., de Lucia, C., Di Gessa, G., Diniz, B. S., Dotchin, C. L., Eaglestone, G., Elliott, B. T., Espeland, M. A., Ferrucci, L. & Fisher, J. & 44 others, Grammatopoulos, D. K., Hardiany, N. S., Hassan-Smith, Z., Hastings, W. J., Jain, S., Joshi, P. K., Katsila, T., Kemp, G. J., Khaiyat, O. A., Lamming, D. W., Gallegos, J. L., Madeo, F., Maier, A. B., Martin-Ruiz, C., Martins, I. J., Mathers, J. C., Mattin, L. R., Merchant, R. A., Moskalev, A., Neytchev, O., Ni Lochlainn, M., Owen, C. M., Phillips, S. M., Pratt, J., Prokopidis, K., Rattray, N. J. W., Rúa-Alonso, M., Schomburg, L., Scott, D., Shyam, S., Sillanpää, E., Tan, M. M. C., Teh, R., Tobin, S. W., Vila-Chã, C. J., Vorluni, L., Weber, D., Welch, A., Wilson, D., Wilson, T., Zhao, T., Philippou, E., Korolchuk, V. I. & Shannon, O. M., 9 Apr 2025, In: Journals of Gerontology: Series A. 80, 5, 12 p., glae297.

      Research output: Contribution to journalArticlepeer-review

      Open Access
      File
      16   Link opens in a new tab Citations (SciVal)
      20 Downloads (Pure)
    • Baseline Characteristics of the TOPaZ Study: Randomised Trial of Teriparatide and Zoledronic Acid Compared with Standard Care in Adults with Osteogenesis Imperfecta

      Hald, J. D., Weir, C., Keerie, C., Dewar, L., MacLean, M., Milne, L., Keen, R., Walsh, J., Poole, K., Langdahl, B., Lindsay, J. R., Ghouri, N., Hollick, R. J., Aspray, T., Crowley, R. K., Cohen-Solal, M., Hassan Smith, Z., Tuck, S., Curtis, E. & Harvey, N. & 23 others, Eekhoff, E. M. W., Feenstra, J., Hampson, G., Stone, M., Turton, J., Patel, P., Siddiqi, M., Munro, R., Roy, M., Paskins, Z., Narayanan, D., Malcolm, E., Javaid, M. K., Osborne, P., Tang, J. C. Y., Lam, W., Moore, D., Black, H. A., Duckworth, A. D., Makaram, N., Guo, T., Stenhouse, G. & Ralston, S. H., 8 Nov 2025, In: Calcified Tissue International and Musculoskeletal Research. 116, 1, p. 136 12 p., 136.

      Research output: Contribution to journalArticlepeer-review

      Open Access
      File
      3 Downloads (Pure)
    • CPD: Challenges in vitamin D deficiency

      Ravat, Z. & Hassan Smith, Z., 21 Aug 2025, Pulse.

      Research output: Contribution to specialist publication or newspaperArticle

      Open Access