Zhuo Wang

2023

Biochemical and Functional Characterization of the Three Zebrafish Transglutaminases 2

Lisetto, M., Fattorini, M., Lanza, A., Gerdol, M., Griffin, M., Wang, Z., Ferrara, F. & Sblattero, D., 27 Jul 2023, In: International Journal of Molecular Sciences. 24, 15, 23 p., 12041.

Research output: Contribution to journal › Article › peer-review

Open Access

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2022

Corrigendum: CDKN2A determines mesothelioma cell fate to EZH2 inhibition

Pinton, G., Wang, Z., Balzano, C., Missaglia, S., Tavian, D., Boldorini, R., Fennell, D. A., Griffin, M. & Moro, L., 23 Nov 2022, In: Frontiers in Oncology. 12, 1 p., 1081632.

Research output: Contribution to journal › Correction › peer-review

Open Access

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2021

CDKN2A Determines Mesothelioma Cell Fate to EZH2 Inhibition

Pinton, G., Wang, Z., Balzano, C., Missaglia, S., Tavian, D., Boldorini, R., Fennell, D. A., Griffin, M. & Moro, L., 1 Jul 2021, In: Frontiers in Oncology. 11, 678447.

Research output: Contribution to journal › Article › peer-review

Open Access

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Transglutaminase 2: a novel therapeutic target for idiopathic pulmonary fibrosis using selective small molecule inhibitors

Fell, S., Wang, Z., Blanchard, A., Nanthakumar, C. & Griffin, M., Feb 2021, In: Amino Acids. 53, 2, p. 205-217 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2019

Mapping the minimum domain of the fibronectin binding site on transglutaminase 2 (TG2) and its importance in mediating signaling, adhesion, and migration in TG2-expressing cells

Soluri, M. F., Boccafoschi, F., Cotella, D., Moro, L., Forestieri, G., Autiero, I., Cavallo, L., Oliva, R., Griffin, M., Wang, Z., Santoro, C. & Sblattero, D., 30 Jan 2019, In: FASEB Journal . 33, 2, p. 2327-2342 16 p.

Research output: Contribution to journal › Article › peer-review

Transglutaminase 2 maintains a colorectal cancer stem phenotype by regulating epithelial-mesenchymal transition

Ayinde, O., Wang, Z., Pinton, G., Moro, L. & Griffin, M., 16 Jul 2019, In: Oncotarget. 10, 44, p. 4556-4569 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2018

Cardiac fibrosis can be attenuated by blocking the activity of transglutaminase 2 using a selective small-molecule inhibitor

Wang, Z., Stuckey, D. J., Murdoch, C. E., Camelliti, P., Lip, G. Y. H. & Griffin, M., 27 Apr 2018, In: Cell Death and Disease. 9, 613.

Research output: Contribution to journal › Article › peer-review

Open Access

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2017

Involvement of cell surface TG2 in the aggregation of K562 cells triggered by gluten

Feriotto, G., Calza, R., Bergamini, C. M., Griffin, M., Wang, Z., Beninati, S., Ferretti, V., Marzola, E., Guerrini, R., Pagnoni, A., Cavazzini, A., Casciano, F. & Mischiati, C., 1 Mar 2017, In: Amino Acids. 49, 3, p. 551–565

Research output: Contribution to journal › Article › peer-review

Open Access

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The functional relationship between transglutaminase 2 and transforming growth factor β1 in the regulation of angiogenesis and endothelial-mesenchymal transition

Wang, Z., Perez, M., Lee, E.-S., Kojima, S. & Griffin, M., 7 Sept 2017, In: Cell Death and Disease. 8, 9, e3032.

Research output: Contribution to journal › Article › peer-review

Open Access

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Tissue transglutaminase (TG2) enables survival of human malignant pleural mesothelioma cells in hypoxia

Zonca, S., Pinton, G., Wang, Z., Soluri, M. F., Tavian, D., Griffin, M., Sblattero, D. & Moro, L., 2 Feb 2017, In: Cell Death and Disease. 8, 2, 7 p., e2592.

Research output: Contribution to journal › Article › peer-review

Open Access

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Tissue transglutaminase induces epithelial-mesenchymal-transition and the acquisition of stem cell like characteristics in colorectal cancer cells

Ayinde, O., Wang, Z. & Griffin, M., 16 Feb 2017, In: Oncotarget. 8, 12, p. 20025-20041 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2016

A novel regulatory role for tissue transglutaminase in epithelial-mesenchymal transition in cystic fibrosis

Nyabam, S., Wang, Z., Thibault, T., Ayinde, O., Basar, R., Marshall, L. & Griffin, M., Sept 2016, In: BBA - Molecular Cell Research. 1863, 9, p. 2234-2244 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2015

Development of potent and selective tissue transglutaminase inhibitors: their effect on TG2 function and application in pathological conditions

Badarau, E., Wang, Z., Rathbone, D. L., Costanzi, A., Thibault, T., Murdoch, C. E., El Alaoui, S., Bartkeviciute, M. & Griffin, M., 22 Oct 2015, In: Chemistry and Biology. 22, 10, p. 1347-1361 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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TG2: a credible therapeutic target in fibrotic diseasedue to its multifunctional roles

Griffin, M., Wang, Z., Thibault, T., Murdoch, C. & Rathbone, D., 31 Aug 2015, In: Amino Acids. 47, 8, p. 1629 1 p.

Research output: Contribution to journal › Conference abstract › peer-review

Transglutaminase 2 interacts with syndecan-4 and CD44 at the surface of human macrophages to promote removal of apoptotic cells

Nadella, V., Wang, Z., Johnson, T. S., Griffin, M. & Devitt, A., Jan 2015, In: BBA - Molecular Cell Research. 1853, 1, p. 201-212 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2014

Cross-linking of collagen I by tissue transglutaminase provides a promising biomaterial for promoting bone healing

Fortunati, D., Chau, D. Y. S., Wang, Z., Collighan, R. J. & Griffin, M., 31 Jul 2014, In: Amino Acids. 46, 7, p. 1751-1761 11 p.

Research output: Contribution to journal › Article › peer-review

2013

A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis

Wang, Z., Perez, M., Caja, S., Melino, G., Johnson, T. S., Lindfors, K. & Griffin, M., 2013, In: Cell Death and Disease. 4, 9, 13 p., e808.

Research output: Contribution to journal › Article › peer-review

Open Access

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Are transglutaminase 2 inhibitors able to reduce gliadin-induced toxicity related to celiac disease? A proof-of-concept study

Rauhavirta, T., Oittinen, M., Kivistö, R., Männistö, P. T., Garcia-Horsman, J. A., Wang, Z., Griffin, M., Mäki, M., Kaukinen, K. & Lindfors, K., Jan 2013, In: Journal of Clinical Immunology. 33, 1, p. 134-142 9 p.

Research output: Contribution to journal › Article › peer-review

The role of TG2 in ECV304-related vasculogenic mimicry

Jones, R. A., Wang, Z., Dookie, S. & Griffin, M., Jan 2013, In: Amino Acids. 44, 1, p. 89-101 13 p.

Research output: Contribution to journal › Article › peer-review

The role of TG2 in regulating S100A4-mediated mammary tumour cell migration

Wang, Z. & Griffin, M., 1 Mar 2013, In: PLoS ONE. 8, 3, 16 p., e57017.

Research output: Contribution to journal › Article › peer-review

Open Access

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Thioredoxin is involved in endothelial cell extracellular transglutaminase 2 activation mediated by celiac disease patient IgA

Nadalutti, C. A., Korponay-Szabo, I. R., Kaukinen, K., Wang, Z., Griffin, M., Mäki, M. & Lindfors, K., 9 Oct 2013, In: PLoS ONE. 8, 10, 12 p., e77277.

Research output: Contribution to journal › Article › peer-review

Open Access

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2012

Characterization of heparin-binding site of tissue transglutaminase: its importance in cell surface targeting, matrix deposition, and cell signaling

Wang, Z., Collighan, R., Pytel, K., Rathbone, D. L., Li, X. & Griffin, M., 13 Apr 2012, In: Journal of Biological Chemistry. 287, 16, p. 13063-13083 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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TG2, a novel extracellular protein with multiple functions

Wang, Z. & Griffin, M., Feb 2012, In: Amino Acids. 42, 2-3, p. 939-949 11 p.

Research output: Contribution to journal › Article › peer-review

2011

Importance of syndecan-4 and syndecan -2 in osteoblast cell adhesion and survival mediated by a tissue transglutaminase-fibronectin complex

Wang, Z., Telci, D. & Griffin, M., 1 Feb 2011, In: Experimental Cell Research. 317, 3, p. 367-381 15 p.

Research output: Contribution to journal › Article › peer-review

Novel Polypeptides and Use Thereof

Collighan, R. (Inventor), Griffin, M. (Inventor), Pytel, K. (Inventor) & Wang, Z. (Inventor), 28 Apr 2011, IPC No. A61K38/04, Patent No. GB 1107147.9

Research output: Patent

Open Access

Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles

Bergamini, C. M., Collighan, R. J., Wang, Z. & Griffin, M., 16 Dec 2011, Advances in enzymology: and related areas of molecular biology. Toone, E. J. (ed.). Hoboken, NJ (US): Wiley, Vol. 78. p. 1-46 46 p.

Research output: Chapter in Book/Published conference output › Chapter

The role of tissue transglutaminase (TG2) in regulating the tumour progression of the mouse colon carcinoma CT26

Kotsakis, P., Wang, Z., Collighan, R. J. & Griffin, M., Oct 2011, In: Amino Acids. 41, 4, p. 909-921 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2010

RGD-independent cell adhesion via a tissue transglutaminase-fibronectin matrix promotes fibronectin fibril deposition and requires syndecan-4/2 and α5β1 integrin co-signaling

Wang, Z., Collighan, R. J., Gross, S. R., Danen, E. H. J., Orend, G., Telci, D. & Griffin, M., 17 Dec 2010, In: Journal of Biological Chemistry. 285, 51, p. 40212-40129 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2009

Experimental testing of the dynamic tracking performance of iGPS and laser tracker

Wang, Z., Maropoulos, P. G., Mastrogiacomo, L. & Franceschini, F., 2009, Laser Metrology and Machine Performance IX : 9th International Conference and Exhibition on Laser Metrology, Machine Tool, CMM and Robotic Performance, LAMDAMAP 2009. Euspen, p. 305-314 10 p.

Research output: Chapter in Book/Published conference output › Conference publication

2008

Fibronectin-tissue transglutaminase matrix rescues RGD-impaired celladhesion through syndecan-4 and β integrin co-signaling

Telci, D., Wang, Z., Li, X., Verderio, E. A. M., Humphries, M. J., Baccarini, M., Basaga, H. & Griffin, M., 25 Jul 2008, In: Journal of Biological Chemistry. 283, 30, p. 20937-20947 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2003

Expression of the human cachexia-associated protein (HCAP) in prostate cancer and in a prostate cancer animal model of cachexia

Wang, Z., Corey, E., Hass, G. M., Higano, C. S., True, L. D., Wallace, D., Tisdale, M. J. & Vessella, R. L., 20 May 2003, In: International Journal of Cancer. 105, 1, p. 123-129 7 p.

Research output: Contribution to journal › Article › peer-review

Zhuo Wang

Research output

Search results