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2019

Durability of glycaemic control with dapagliflozin, an SGLT2 inhibitor, compared with saxagliptin, a DPP4 inhibitor, in patients with inadequately controlled type 2 diabetes

Bailey, C. J., Del Prato, S., Wei, C., Reyner, D. & Saraiva, G., 1 Nov 2019, In : Diabetes, Obesity and Metabolism. 21, 11, p. 2564-2569 6 p.

Research output: Contribution to journalArticle

Open Access
File
Type 2 Diabetes Mellitus
Metformin
saxagliptin
2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol
Placebos

FDA guidance on cardiovascular risk of antidiabetic therapies: one decade later

Bailey, C. J., 1 May 2019, In : Diabetes, Obesity and Metabolism. 21, 5, p. 1079-1080 2 p.

Research output: Contribution to journalComment/debate

rosiglitazone
Hypoglycemic Agents
Industry
Head
Safety

GIP analogues and the treatment of obesity-diabetes

Bailey, C. J., 19 Nov 2019, In : Peptides.

Research output: Contribution to journalArticle

Gastric Inhibitory Polypeptide
Medical problems
Obesity
Type 2 Diabetes Mellitus
Therapeutics

Insulin resistance: Impact on therapeutic developments in diabetes

Bailey, C. J., 23 Apr 2019, In : Diabetes and Vascular Disease Research. 16, 2, p. 128-132 5 p.

Research output: Contribution to journalReview article

Open Access
File
Insulin Resistance
Therapeutics
Thiazolidinediones
Metformin
Hyperinsulinism

Phenotypic characteristics and risk factors in a multi-ethnic cohort of young adults with type 2 diabetes

Lascar, N., Altaf, Q-A., Raymond, N. T., Brown, J. E., Pattison, H., Barnett, A., Bailey, C. J. & Bellary, S., 2 Nov 2019, In : Current Medical Research and Opinion. 35, 11, p. 1893-1900 8 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Young Adult
Diabetes Complications
Ovarian Diseases
Exercise

Reports of Lactic Acidosis Attributed to Metformin, 2015–2018

Flory, J. H., Hennessy, S., Bailey, C. J. & Inzucchi, S. E., 9 Oct 2019, In : Diabetes Care.

Research output: Contribution to journalArticle

Lactic Acidosis
Metformin
Information Storage and Retrieval
United States Food and Drug Administration
Chronic Renal Insufficiency

Rotational culture and integration with amniotic stem cells reduce porcine islet immunoreactivity in vitro and slow xeno‐rejection in a murine model of islet transplantation

Zafar, A., Lee, J., Yesmin, S., Paget, M. B., Bailey, C. J., Murray, H. E. & Downing, R., 1 Jul 2019, In : Xenotransplantation. 26, 4, e12508.

Research output: Contribution to journalArticle

Islets of Langerhans Transplantation
Swine
Stem Cells
Transplants
Epithelial Cells

The future of new drugs for diabetes management

Bailey, C. J. & Day, C., 1 Sep 2019, In : Diabetes Research and Clinical Practice. 155, 107785.

Research output: Contribution to journalReview article

Sodium-Glucose Transporter 2
Type 2 Diabetes Mellitus
Symporters
Kidney
Pharmaceutical Preparations

Treating T2DM and obesity with bariatric surgery and GLP1 agents

Bailey, C. J., 22 Jul 2019, In : Nature Reviews Endocrinology. 15, 9, p. 504–506 3 p.

Research output: Contribution to journalComment/debate

Bariatric Surgery
Hyperglycemia
Obesity
Type 2 Diabetes Mellitus
Prospective Studies

Uric acid and the cardio-renal effects of SGLT2 inhibitors

Bailey, C. J., 1 Jun 2019, In : Diabetes, Obesity and Metabolism. 21, 6, p. 1291-1298 8 p.

Research output: Contribution to journalReview article

Uric Acid
Sodium
Kidney
Glucose
Type 2 Diabetes Mellitus

Weight lowering treatments in type 2 diabetes

Bailey, C., 14 Jan 2019, In : Endocrine Abstracts. 61, OU7.

Research output: Contribution to journalMeeting abstract

2018
Open Access
File
Type 2 Diabetes Mellitus
Glucose
Sodium-Glucose Transporter 2
Therapeutics
Heart Failure

European Medicines Agency: approval of new glucose-lowering medicines for type 2 diabetes

Bailey, C. J., 13 May 2018, In : Diabetes, Obesity and Metabolism. 20, 9, p. 2057-2058

Research output: Contribution to journalArticle

Open Access
File
Information Storage and Retrieval
Marketing
Type 2 Diabetes Mellitus
Clinical Trials
Glucose

Glucose-lowering therapies in type 2 diabetes: Opportunities and challenges for peptides

Bailey, C. J., 3 Feb 2018, In : Peptides. 100, p. 9-17

Research output: Contribution to journalArticle

Open Access
File
Medical problems
Type 2 Diabetes Mellitus
Glucose
Peptides
Insulin

Treatment of type 2 diabetes: future approaches

Bailey, C. J. & Day, C., 18 Apr 2018, In : British Medical Bulletin. 126, 1, p. 123-137

Research output: Contribution to journalReview article

Open Access
File
Type 2 Diabetes Mellitus
Glucose
PubMed
Hyperglycemia
Blood Glucose
2017

Ambulatory glucose profile (AGP): utility in UK clinical practice

Evans, M., Cranston, I. & Bailey, C. J., 21 Mar 2017, In : British Journal of Diabetes. 17, 1, p. 26-33 8 p.

Research output: Contribution to journalArticle

Glucose
Hypoglycemia
Diabetes Complications
Hyperglycemia
Blood Glucose

Dapagliflozin in patients with type 2 diabetes mellitus: a pooled analysis of safety data from phase IIb/III clinical trials

Jabbour, S., Seufert, J., Scheen, A., Bailey, C. J., Karup, C. & Langkilde, A. M., 26 Oct 2017, In : Diabetes, Obesity and Metabolism. Early view, 9 p.

Research output: Contribution to journalArticle

Open Access
File
Phase III Clinical Trials
Type 2 Diabetes Mellitus
Safety
Placebos
Diabetic Ketoacidosis

Dapagliflozin therapy for type 2 diabetes in primary care: changes in HbA1c, weight and blood pressure over 2 years follow-up

Wilding, J., Bailey, C., Rigney, U., Blak, B., Kok, M. & Emmas, C., 1 Oct 2017, In : Primary Care Diabetes. 11, 5, p. 437-444 8 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Primary Health Care
Blood Pressure
Weights and Measures
Weight Loss

Gaps and barriers in the control of blood glucose in people with type 2 diabetes

Blonde, L., Aschner, P., Bailey, C., Ji, L., Leiter, L. A. & Matthaei, S., 1 May 2017, In : Diabetes and Vascular Disease Research. 14, 3, p. 172-183 12 p.

Research output: Contribution to journalReview article

Open Access
File
Type 2 Diabetes Mellitus
Blood Glucose
Publications
Literature
PubMed

Metformin: historical overview

Bailey, C. J., Sep 2017, In : Diabetologia. 60, 9, p. 1566–1576 11 p.

Research output: Contribution to journalComment/debate

Open Access
File
Metformin
Galega
Biguanides
Blood Glucose
Guanidine

Metformin extended-release versus immediate-release: An international, randomized, double-blind, head-to-head trial in pharmacotherapy-naïve patients with type 2 diabetes

Aggarwal, N., Singla, A., Mathieu, C., Montanya, E., Pfeiffer, A. F. H., Johnsson, E., Zhao, J., Iqbal, N. & Bailey, C., 2 Oct 2017, In : Diabetes, Obesity and Metabolism. Early online

Research output: Contribution to journalArticle

Open Access
File
Metformin
Type 2 Diabetes Mellitus
Drug Therapy
Glucose
Fasting

Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels

Rana, K. S., Pararasa, C., Afzal, I., Nagel, D. A., Hill, E. J., Bailey, C. J., Griffiths, H. R., Kyrou, I., Randeva, H. S., Bellary, S. & Brown, J. E., 9 Nov 2017, In : Cardiovascular Diabetology. 16, 1

Research output: Contribution to journalArticle

Open Access
File
E-Selectin
Type 2 Diabetes Mellitus
Obesity
Adiposity
Adipose Tissue

The interdisciplinary team in type 2 diabetes management: challenges and best practice solutions from real-world scenarios

McGill, M., Blonde, L., Chan, J. C. N., Khunti, K., Lavalle, F. J. & Bailey, C. J., Mar 2017, In : Journal of Clinical and Translational Endocrinology. 7, p. 21-27 7 p.

Research output: Contribution to journalReview article

Open Access
File
Practice Guidelines
Type 2 Diabetes Mellitus
Diabetes Complications
Patient Care
Communication

Type 2 diabetes in adolescents and young adults

Lascar, N., Brown, J., Pattison, H., Barnett, A. H., Bailey, C. J. & Bellary, S., 5 Oct 2017, In : The Lancet Diabetes and Endocrinology. in press

Research output: Contribution to journalArticle

Open Access
File
Type 2 Diabetes Mellitus
Young Adult
Sedentary Lifestyle
Risk Management
Causality
2016

Age-associated changes in long-chain fatty acid profile during healthy aging promote pro-inflammatory monocyte polarization via PPARγ

Pararasa, C., Ikwuobe, J., Shigdar, S., Boukouvalas, A., Nabney, I. T., Brown, J. E., Devitt, A., Bailey, C. J., Bennett, S. J. & Griffiths, H. R., Feb 2016, In : Aging Cell. 15, 1, p. 128-139 12 p.

Research output: Contribution to journalArticle

Open Access
File
Peroxisome Proliferator-Activated Receptors
Monocytes
Fatty Acids
Ceramides
Macrophages

Ciglitazone

Day, C. & Bailey, C., 2016, Reference module in biomedical sciences. Elsevier

Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

Thiazolidinediones
rosiglitazone
pioglitazone
troglitazone
PPAR gamma

Future glucose-lowering drugs for type 2 diabetes

Bailey, C. J., Tahrani, A. A. & Barnett, A. H., 23 Jan 2016, In : The Lancet Diabetes and Endocrinology. 4, 4, p. 350-359 10 p.

Research output: Contribution to journalReview article

Open Access
File
Type 2 Diabetes Mellitus
Incretins
Glucose
Pharmaceutical Preparations
Sodium-Glucose Transport Proteins

Glycated hemoglobin, body weight and blood pressure in type 2 diabetes patients initiating dapagliflozin treatment in primary care: a retrospective study

Wilding, J., Bailey, C., Rigney, U., Blak, B., Beekman, W. & Emmas, C., 1 Sep 2016, In : Diabetes Therapy. 7, 4, p. 695-711 17 p.

Research output: Contribution to journalArticle

Open Access
File
Glycosylated Hemoglobin A
Type 2 Diabetes Mellitus
Primary Health Care
Retrospective Studies
Body Weight

Metformin and the gastrointestinal tract

McCreight, L. J., Bailey, C. J. & Pearson, E. R., 1 Mar 2016, In : Diabetologia. 59, 3, p. 426-435 10 p.

Research output: Contribution to journalArticle

Open Access
File
Metformin
Gastrointestinal Tract
Glucagon-Like Peptide 1
Microbiota
Bile Acids and Salts

Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus

Tahrani, A. A., Barnett, A. H. & Bailey, C. J., Oct 2016, In : Nature Reviews Endocrinology. 12, 10, p. 566–592 27 p.

Research output: Contribution to journalReview article

Open Access
File
Type 2 Diabetes Mellitus
Pharmacology
Pharmaceutical Preparations
Safety
Therapeutics

Timely intervention in type 2 diabetes: achieving early and sustained glycemic control

Bailey, C. J., 1 Jan 2016, Medicographia, 38, 1, p. 3-8 6 p.

Research output: Contribution to specialist publicationEditorial

Under-treatment of type 2 diabetes: causes and outcomes of clinical inertia

Bailey, C. J., Dec 2016, In : International Journal of Clinical Practice. 70, 12, p. 988-995 8 p.

Research output: Contribution to journalReview article

Type 2 Diabetes Mellitus
Guidelines
Therapeutics
Glycosylated Hemoglobin A
PubMed
2015

Ageing, adipose tissue, fatty acids and inflammation

Pararasa, C., Bailey, C. J. & Griffiths, H. R., Jan 2015, In : Biogerontology. 16, 2, p. 235-248 14 p.

Research output: Contribution to journalArticle

Open Access
File
Adipose Tissue
Fatty Acids
Nonesterified Fatty Acids
Adipocytes
Inflammation

Cardiovascular outcome trials in type 2 diabetes – 2015

Day, C. & Bailey, C. J., 2015, Diabesity in practice, 4, 4, p. 131-133 3 p.

Research output: Contribution to specialist publicationBook/Film/Article review

rosiglitazone
United States Food and Drug Administration
Type 2 Diabetes Mellitus
Safety
Marketing

Changes in HbA1c and weight in type 2 diabetes patients initiating dapagliflozin treatment in routine UK primary care

Wilding, J. P. H., Bailey, C. J., Rigney, U., Blak, B., Beekman, W. & Emmas, C. E., Sep 2015, In : Diabetologia. 58, Suppl.1, p. S352-S356 2 p., 737.

Research output: Contribution to journalMeeting abstract

Type 2 Diabetes Mellitus
Primary Health Care
Weights and Measures
Prescriptions
Metformin

Efficacy and safety of dapagliflozin monotherapy in people with Type 2 diabetes: a randomized double-blind placebo-controlled 102-week trial

Bailey, C. J., Morales Villegas, E. C., Woo, V., Tang, W., Ptaszynska, A. & List, J. F., 30 Apr 2015, In : Diabetic Medicine. 32, 4, p. 531-541 11 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Metformin
Placebos
Safety
Sodium-Glucose Transport Proteins

Low gravity rotational culture and the integration of immunomodulatory stem cells reduce human islet allo-reactivity

Qureshi, K. M., Lee, J., Paget, M. B., Bailey, C. J., Curnow, S. J., Murray, H. E. & Downing, R., Jan 2015, In : Clinical Transplantation. 29, 1, p. 90-98 9 p.

Research output: Contribution to journalArticle

Hypogravity
Stem Cells
Epithelial Cells
T-Lymphocyte Subsets
Transplants

Pharmacotherapies to manage diabesity: an update

Day, C. & Bailey, C. J., 2015, In : Diabesity in practice. 4, 1, p. 14-23 10 p.

Research output: Contribution to journalArticle

Hypoglycemia
Weight Loss
Metformin
Glucose
Drug Therapy

Safety of antidiabetes medications: an update

Bailey, C. J., 31 Aug 2015, In : Clinical pharmacology and therapeutics. 98, 2, p. 185–195 11 p.

Research output: Contribution to journalArticle

Reproductive Tract Infections
Bone Neoplasms
Bone Fractures
Hypoglycemic Agents
Urinary Tract Infections

The current drug treatment landscape for diabetes and perspectives for the future

Bailey, C. J., 31 Aug 2015, In : Clinical pharmacology and therapeutics. 98, 2, p. 170–184 15 p.

Research output: Contribution to journalArticle

Hyperglycemia
Pharmaceutical Preparations
Type 2 Diabetes Mellitus
Blood Glucose
Therapeutics