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Abstract

Mass spectrometry based method for measurement of oxysterols

Dias, I. H. K., Milic, I., Devitt, A., Spickett, C. M., Pitt, A. R. & Griffiths, H. R., 1 Jul 2016, p. S27.

Research output: Contribution to conference › Abstract

The effect of cellular oxidative stress on PTEN interactions

Kativu, P., Pitt, A. R. & Spickett, C. M., 1 Jul 2016, p. S57-S58.

Research output: Contribution to conference › Abstract

Phosphoric Monoester Hydrolases

Oxidation-Reduction

Oxidative Stress

Thioredoxins

Phosphatidylinositol 3-Kinases

Article

A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells

Knight, A. R., Taylor, E., Lukaszewski, R., Tveen Jensen, K., Jones, H. E., Carré, J. E., supov, M. N. I., Littlechild, J. A., Bailey, S. J., Brewer, E., McDonald, T. J., Pitt, A. R., Spickett, C. M. & Winyard, P. G., 20 May 2018, In : Free Radical Biology and Medicine. 120, p. 246-254

Research output: Contribution to journal › Article

Open Access

File

Immunosorbents

Oxidative stress

Biomarkers

Assays

Blood Cells

A mass spectrometry approach for the identification and localization of small aldehyde modifications of proteins

Afonso, C. B., Sousa, B. C., Pitt, A. R. & Spickett, C. M., 15 May 2018, In : Archives of Biochemistry and Biophysics. 646, p. 38-45

Research output: Contribution to journal › Article

Open Access

File

Acrolein

Aldehydes

Mass spectrometry

Mass Spectrometry

Muramidase

Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein

Teo, A. C. K., Lee, S. C., Pollock, N. L., Stroud, Z., Hall, S., Thakker, A., Pitt, A. R., Dafforn, T. R., Spickett, C. M. & Roper, D. I., 12 Feb 2019, In : Scientific Reports. 9, 1, 1813.

Research output: Contribution to journal › Article

Open Access

File

Bacterial Proteins

Phospholipids

Membrane Proteins

Lipids

Styrene

Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds

Sousa, B. C., Pitt, A. R. & Spickett, C. M., 10 Feb 2017, In : Free Radical Biology and Medicine. In press

Research output: Contribution to journal › Article

Open Access

File

Aldehydes

Lipids

Oxidation

Phospholipids

2-butenal

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162]

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçin, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., 26 Oct 2017, In : Redox Biology. In press

Research output: Contribution to journal › Article

Open Access

File

Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies

Campos-pinto, I., Méndez, L., Schouten, J., Wilkins, J., Fedorova, M., Pitt, A., Davis, P. & Spickett, C., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 234-244 11 p.

Research output: Contribution to journal › Article

Open Access

File

Epitope Mapping

Serum Albumin

Epitopes

Antibodies

Peptides

European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST Action BM1203 (EU-ROS)

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec–butuner, B., Dias, I., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L-O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K-H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., Mcbean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P-A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., di Lisa, F. & Daiber, A., 1 Oct 2017, In : Redox biology. 13, p. 94-162 69 p.

Research output: Contribution to journal › Article

Open Access

File

Reactive Nitrogen Species

Oxidation-Reduction

Oxidative stress

Technology

Reactive Oxygen Species

Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS

Ni, Z., Sousa, B. C., Colombo, S., Afonso, C. B., Melo, T., Pitt, A. R., Spickett, C. M., Domingues, P., Domingues, M. R., Fedorova, M. & Criscuolo, A., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 156-166 11 p.

Research output: Contribution to journal › Article

Open Access

File

Air

Lipids

Lipid Peroxidation

Oxidation

Arachidonic Acids

Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration

Rossin, D., Dias, I. H. K., Solej, M., Milic, I., Pitt, A. R., Iaia, N., Scoppapietra, L., Devitt, A., Nano, M., Degiuli, M., Volante, M., Caccia, C., Leoni, V., Griffiths, H. R., Spickett, C. M., Poli, G. & Biasi, F., 20 May 2019, In : Free Radical Biology and Medicine. 136, p. 35-44 10 p.

Research output: Contribution to journal › Article

Infiltration

Colorectal Neoplasms

Cell Survival

Cells

Tumors

Interfacing low-energy SAW nebulization with liquid chromatography-mass spectrometry for the analysis of biological samples

Tveen Jensen, K., Gesellchen, F., Wilson, R., Spickett, C., Cooper, J. M. & Pitt, A., 15 May 2015, In : Scientific Reports. 5, 5 p., 9736.

Research output: Contribution to journal › Article

Open Access

File

Liquid chromatography

Surface waves

Mass spectrometry

Mass spectrometers

Acoustic waves

Oxidiative lipidomics coming of age: advances in analysis of oxidized phospholipids in physiology and pathology

Spickett, C. M. & Pitt, A. R., 20 Jun 2015, In : Antioxidants and Redox Signaling. 22, 18, p. 1646-1666 21 p.

Research output: Contribution to journal › Article

Open Access

File

Physiology

Pathology

Mass spectrometry

Mass Spectrometry

Phospholipids

PARP1 Co-regulates EP300–BRG1-dependent transcription of genes involved in breast cancer cell proliferation and DNA repair

Sobczak, M., Pitt, A. R., Spickett, C. M. & Robaszkiewicz, A., 11 Oct 2019, In : Cancers. 11, 10, 1539.

Research output: Contribution to journal › Article

Open Access

File

DNA Repair

Cell Proliferation

Breast Neoplasms

Genes

Adenosine Diphosphate

Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins

Verrastro, I., Tveen-Jensen, K., Woscholski, R., Spickett, C. M. & Pitt, A. R., 1 Jan 2016, In : Free Radical Biology and Medicine. 90, p. 24-34 11 p.

Research output: Contribution to journal › Article

Open Access

File

Phosphoric Monoester Hydrolases

Oxidation

Oxidation-Reduction

Proteins

Dual-Specificity Phosphatases

Short-chain lipid peroxidation products form covalent adducts with pyruvate kinase and inhibit its activity in vitro and in breast cancer cells

Costa Sousa, B., Ahmed, T., Dann, W. L., Ashman, J., Guy, A., Durand, T., Pitt, A. R. & Spickett, C. M., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 223-233 11 p.

Research output: Contribution to journal › Article

Open Access

File

Pyruvate Kinase

Aldehydes

Lipid Peroxidation

Cells

Breast Neoplasms

The effect of HOCl-induced modifications on phosphatase and tensin homolog (PTEN) structure and function

Verrastro, I., Tveen Jensen, K., Spickett, C. M. & Pitt, A. R., 3 Jan 2018, In : Free Radical Research. p. 1-471

Research output: Contribution to journal › Article

Open Access

File

Hypochlorous Acid

Phosphoric Monoester Hydrolases

Oxidation

Tyrosine

Proteins

Top-down lipidomics of low density lipoprotein reveal altered lipid profiles in advanced chronic kidney disease

Reis, A., Rudnitskaya, A., Chariyavilaskul, P., Dhaun, N., Melville, V., Goddard, J., Webb, D. J., Pitt, A. R. & Spickett, C. M., 1 Feb 2015, In : Journal of Lipid Research. 56, 2, p. 413-422 10 p.

Research output: Contribution to journal › Article

Open Access

File

Chronic Renal Insufficiency

LDL Lipoproteins

Lipids

Ethanolamines

Sulfoglycosphingolipids

Meeting abstract

Analysis of phospholipid peroxidation and protein lipoxidation products by LC-MS

Spickett, C. M., Sousa, B. C. & Pitt, A. R., 15 Aug 2018, In : Free Radical Biology and Medicine. 124, p. 560

Research output: Contribution to journal › Meeting abstract

Phospholipids

Proteins

Bioactivity

Mass spectrometry

Apolipoprotein B-100

Developing targeted mass spectrometry approaches for the identification of protein lipoxidation

Spickett, C. M., Bhurrut, E. J. B., Sousa, B. C., Afonso, C. B., Durand, T. & Pitt, A. R., 14 May 2018, In : Free Radical Biology and Medicine. 120, Suppl 1, p. S86-S87

Research output: Contribution to journal › Meeting abstract