Find Research Outputs

Search in all content

Filters for Research Outputs

Search concepts
Selected filters

Publication Year

  • 2019
  • 2017
  • 2016
  • 2015

Author

  • David Poyner
2015

G-protein-coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent

Jamshad, M., Charlton, J., Lin, Y-P., Routledge, S. J., Bawa, Z., Knowles, T. J., Overduin, M., Dekker, N., Dafforn, T. R., Bill, R. M., Poyner, D. R. & Wheatley, M., 27 Feb 2015, In : Bioscience Reports. 35, 2, 10 p., e00188.

Research output: Contribution to journalArticle

Open Access
File

Modulation of glucagon receptor pharmacology by Receptor Activity-modifying Protein-2 (RAMP2)

Weston, C., Lu, J., Li, N., Barkan, K., Richards, G. O., Roberts, D. J., Skerry, T. M., Poyner, D., Pardamwar, M., Reynolds, C. A., Dowell, S. J., Willars, G. B. & Ladds, G., 18 Sep 2015, In : Journal of Biological Chemistry. 290, 38, p. 23009-23022 14 p.

Research output: Contribution to journalArticle

Open Access
File

Structural basis for receptor activity-modifying protein-dependent selective peptide recognition by a G protein-coupled receptor

Booe, JM., Walker, C. S., Barwell, J., Kuteyi, G., Simms, J., Jamaluddin, MA., Warner, ML., Bill, R. M., Harris, PW., Brimble, MA., Poyner, D. R., Hay, D. L. & Pioszak, AA., 18 Jun 2015, In : Molecular Cell. 58, 6, p. 1040-1052 13 p.

Research output: Contribution to journalArticle

Open Access
File
2016

An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology

Gingell, J. J., Simms, J., Barwell, J., Poyner, D. R., Watkins, H. A., Pioszak, AA., Sexton, P. M. & Hay, D. L., 17 May 2016, In : Cell Discovery. 2, 16012.

Research output: Contribution to journalArticle

Open Access
File

GPCR-styrene maleic acid lipid particles (GPCR-SMALPs): their nature and potential

Wheatley, M., Charlton, J., Jamshad, M., Routledge, S. J., Bailey, S., La-Borde, P. J., Azam, M. T., Logan, R. T., Bill, R. M., Dafforn, T. R. & Poyner, D. R., 15 Apr 2016, In : Biochemical Society Transactions. 44, 2, p. 619-623 5 p.

Research output: Contribution to journalReview article

Open Access
File

Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors

Weston, C., Winfield, I., Harris, M., Hodgson, R., Shah, A., Dowell, S. J., Mobarec, J. C., Woodlock, D. A., Reynolds, C. A., Poyner, D. R., Watkins, H. A. & Ladds, G., 14 Oct 2016, In : Journal of Biological Chemistry. 291, 42, p. 21925-21944 20 p.

Research output: Contribution to journalArticle

Open Access
File

Receptor activity-modifying proteins; multifunctional G protein-coupled receptor accessory proteins

Hay, D. L., Walker, C. S., Gingell, J. J., Ladds, G., Reynolds, C. A. & Poyner, D. R., 15 Apr 2016, In : Biochemical Society Transactions. 44, 2, p. 568-573 6 p.

Research output: Contribution to journalReview article

Receptor activity-modifying proteins 2 and 3 generate adrenomedullin receptor subtypes with distinct molecular properties

Watkins, H. A., Chakravarthy, M., Abhayawardana, R. S., Gingell, J. J., Garelja, M., Pardamwar, M., McElhinney, J. M. W. R., Lathbridge, A., Constantine, A., Harris, P. W. R., Yuen, T-Y., Brimble, M. A., Barwell, J., Poyner, D. R., Woolley, M. J., Conner, A. C., Pioszak, AA., Reynolds, C. A. & Hay, D. L., 27 May 2016, In : Journal of Biological Chemistry. 291, 22, p. 11657-11675 19 p.

Research output: Contribution to journalArticle

Open Access
File
2017

Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs

Woolley, M. J., Reynolds, C. A., Simms, J., Walker, C. S., Mobarec, J. C., Garelja, M. L., Conner, A. C., Poyner, D. R. & Hay, D. L., 15 Oct 2017, In : Biochemical Pharmacology. 142, p. 96-110

Research output: Contribution to journalArticle

Open Access
File
Open Access
File

The effects of RAMPs upon cell signalling

Routledge, S. J., Ladds, G. & Poyner, D. R., 5 Apr 2017, In : Molecular and Cellular Endocrinology. in press

Research output: Contribution to journalArticle

Open Access
File
Open Access
File

Update on the pharmacology of calcitonin/CGRP family of peptides: IUPHAR Review 25

Hay, D. L., Garelja, M. L., Poyner, D. R. & Walker, C. S., 28 Nov 2017, In : British Journal of Pharmacology. In press, 41 p.

Research output: Contribution to journalArticle

Open Access
File
2019

Interactions Between RAMP2 And CRF Receptors: The Effect Of Receptor Subtypes, Splice Variants And Cell Context

Bailey, S., Harris, M., Barkan, K., Winfield, I., Thomas-Harper, M., Simms, J. W., Ladds, G., Wheatley, M. & Poyner, D. R., 1 May 2019, In : BBA -Biomembranes. 1861, 5, p. 997-1003 7 p.

Research output: Contribution to journalArticle

Open Access
File