A concise synthesis of isoguanine 2’-deoxyriboside and its adenine-like triplex formation when incorporated into DNA

Keyphrases

• Deoxyribose 100%
• Isoguanine 100%
• Concise Synthesis 100%
• Triplex Formation 100%
• 2′-deoxyadenosine 66%
• Ammonia 33%
• Regioisomers 33%
• Phosphoramidite 33%
• Sodium 33%
• Chloro 33%
• Nucleosides 33%
• Deprotection 33%
• Oligomerization 33%
• 2,6-Dichloropurine 33%
• Chromatographic Separation 33%
• Hydrogenolysis 33%
• Chlorine Atom 33%
• Allyloxy 33%
• Solid Synthesis 33%
• Benzyl Group 33%
• Aminated 33%
• Single Isomer 33%
• Methanolic 33%
• DNA Melting 33%
• Allyl Group 33%

Chemistry

• formation 100%
• Deoxyribonucleic Acid 100%
• Adenine 100%
• Isoguanine 100%
• Phosphoramidite 33%
• Sodium 33%
• Nucleoside 33%
• Purity 33%
• Oligomerization 33%
• Cladribine 33%
• Chromatography 33%
• Hydrogenolysis 33%
• Melting Point 33%
• Chlorine Atom 33%
• Benzyl Group 33%
• Allyl Group 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Adenine 100%
• Deoxyadenosine 50%
• Nucleoside 50%
• Phosphoramidous Acid 50%
• Cladribine 50%
• Allyl Compound 50%