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A Guideline for Reporting Mediation Analyses of Randomized Trials and Observational Studies: The AGReMA Statement

  • Hopin Lee
  • , Aidan G. Cashin
  • , Sarah E. Lamb
  • , Sally Hopewell
  • , Stijn Vansteelandt
  • , Tyler J. VanderWeele
  • , David P. MacKinnon
  • , Gemma Mansell
  • , Gary S. Collins
  • , Robert M. Golub
  • , James H. McAuley
  • , A. Russell Localio
  • , Ludo van Amelsvoort
  • , Eliseo Guallar
  • , Judith Rijnhart
  • , Kimberley Goldsmith
  • , Amanda J. Fairchild
  • , Cara C. Lewis
  • , Steven J. Kamper
  • , Christopher M. Williams
  • Nicholas Henschke
  • Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, England,School of Medicine and Public Health, University of Newcastle, Callaghan, Australia
  • Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia,Neuroscience Research Australia, Sydney
  • Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, England,College of Medicine and Health, University of Exeter Medical School, Exeter, England
  • Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, England
  • Department of Applied Mathematics, Computer Science, and Statistics, Ghent University, Ghent, Belgium,Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, England
  • Departments of Epidemiology and Biostatistics, T. H. Chan School of Public Health, Harvard University, Boston, Massachusetts
  • Department of Psychology, Arizona State University, Phoenix
  • Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, England,NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, England
  • JAMA Editorial Office, Chicago, Illinois,Division of General Internal Medicine and Geriatrics, Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
  • Neuroscience Research Australia, Sydney,School of Health Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia
  • Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia,Associate Editor, Annals of Internal Medicine
  • Faculty of Health, Medicine, and Life Sciences, Maastricht University, Maastricht, the Netherlands,Assoicate Editor, Journal of Clinical Epidemiology
  • Welch Center for Prevention, Epidemiology, and Clinical Research, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland,Deputy Editor, Annals of Internal Medicine
  • Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands
  • Institute of Psychiatry, Psychology, and Neuroscience, King’s College London, London, England
  • Department of Psychology, University of South Carolina, Columbia
  • Kaiser Permanente Washington Health Research Institute, Seattle
  • School of Health Sciences, University of Sydney, Sydney, Australia,Nepean Blue Mountains Local Health District, Kingswood, Australia
  • School of Medicine and Public Health, University of Newcastle, Callaghan, Australia
  • School of Public Health, University of Sydney, Sydney, Australia

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