A naturally shaped silicone ventricle evaluated in a mock circulation loop: a preliminary study

S. Gregory, D. Timms, M.J. Pearcy, Geoff D. Tansley

Research output: Contribution to journalArticle

Abstract

Mock circulation loops are used to evaluate the performance of cardiac assist devices prior to animal and clinical testing. A compressible, translucent silicone ventricle chamber that mimics the exact size, shape and motion of a failing heart is desired to assist in flow visualization studies around inflow cannulae during VAD support. The aim of this study was therefore to design and construct a naturally shaped flexible left ventricle and evaluate its performance in a mock circulation loop. The ventricle shape was constructed by the use of CT images taken from a patient experiencing cardiomyopathic heart failure and used to create a 3D image and subsequent mould to produce a silicone ventricle. Different cardiac conditions were successfully simulated to validate the ventricle performance, including rest, left heart failure and VAD support.
Original languageEnglish
Pages (from-to)185-191
Number of pages7
JournalJournal of Medical Engineering and Technology
Volume33
Issue number3
DOIs
Publication statusPublished - Apr 2009

Fingerprint

Silicones
Flow visualization
Animals
Testing

Keywords

  • ventricular assist device
  • mock circulation loop
  • silicone ventricle

Cite this

Gregory, S. ; Timms, D. ; Pearcy, M.J. ; Tansley, Geoff D. / A naturally shaped silicone ventricle evaluated in a mock circulation loop: a preliminary study. In: Journal of Medical Engineering and Technology. 2009 ; Vol. 33, No. 3. pp. 185-191.
@article{578f6d1995194cb7adb144f70d0f0f83,
title = "A naturally shaped silicone ventricle evaluated in a mock circulation loop: a preliminary study",
abstract = "Mock circulation loops are used to evaluate the performance of cardiac assist devices prior to animal and clinical testing. A compressible, translucent silicone ventricle chamber that mimics the exact size, shape and motion of a failing heart is desired to assist in flow visualization studies around inflow cannulae during VAD support. The aim of this study was therefore to design and construct a naturally shaped flexible left ventricle and evaluate its performance in a mock circulation loop. The ventricle shape was constructed by the use of CT images taken from a patient experiencing cardiomyopathic heart failure and used to create a 3D image and subsequent mould to produce a silicone ventricle. Different cardiac conditions were successfully simulated to validate the ventricle performance, including rest, left heart failure and VAD support.",
keywords = "ventricular assist device, mock circulation loop, silicone ventricle",
author = "S. Gregory and D. Timms and M.J. Pearcy and Tansley, {Geoff D.}",
year = "2009",
month = "4",
doi = "10.1080/03091900802184072",
language = "English",
volume = "33",
pages = "185--191",
journal = "Journal of Medical Engineering and Technology",
issn = "0309-1902",
publisher = "Informa Healthcare",
number = "3",

}

A naturally shaped silicone ventricle evaluated in a mock circulation loop: a preliminary study. / Gregory, S.; Timms, D.; Pearcy, M.J.; Tansley, Geoff D.

In: Journal of Medical Engineering and Technology, Vol. 33, No. 3, 04.2009, p. 185-191.

Research output: Contribution to journalArticle

TY - JOUR

T1 - A naturally shaped silicone ventricle evaluated in a mock circulation loop: a preliminary study

AU - Gregory, S.

AU - Timms, D.

AU - Pearcy, M.J.

AU - Tansley, Geoff D.

PY - 2009/4

Y1 - 2009/4

N2 - Mock circulation loops are used to evaluate the performance of cardiac assist devices prior to animal and clinical testing. A compressible, translucent silicone ventricle chamber that mimics the exact size, shape and motion of a failing heart is desired to assist in flow visualization studies around inflow cannulae during VAD support. The aim of this study was therefore to design and construct a naturally shaped flexible left ventricle and evaluate its performance in a mock circulation loop. The ventricle shape was constructed by the use of CT images taken from a patient experiencing cardiomyopathic heart failure and used to create a 3D image and subsequent mould to produce a silicone ventricle. Different cardiac conditions were successfully simulated to validate the ventricle performance, including rest, left heart failure and VAD support.

AB - Mock circulation loops are used to evaluate the performance of cardiac assist devices prior to animal and clinical testing. A compressible, translucent silicone ventricle chamber that mimics the exact size, shape and motion of a failing heart is desired to assist in flow visualization studies around inflow cannulae during VAD support. The aim of this study was therefore to design and construct a naturally shaped flexible left ventricle and evaluate its performance in a mock circulation loop. The ventricle shape was constructed by the use of CT images taken from a patient experiencing cardiomyopathic heart failure and used to create a 3D image and subsequent mould to produce a silicone ventricle. Different cardiac conditions were successfully simulated to validate the ventricle performance, including rest, left heart failure and VAD support.

KW - ventricular assist device

KW - mock circulation loop

KW - silicone ventricle

UR - http://www.scopus.com/inward/record.url?scp=67651154192&partnerID=8YFLogxK

UR - http://informahealthcare.com/doi/full/10.1080/03091900802184072

U2 - 10.1080/03091900802184072

DO - 10.1080/03091900802184072

M3 - Article

VL - 33

SP - 185

EP - 191

JO - Journal of Medical Engineering and Technology

JF - Journal of Medical Engineering and Technology

SN - 0309-1902

IS - 3

ER -