Mock circulation loops are used to evaluate the performance of cardiac assist devices prior to animal and clinical testing. A compressible, translucent silicone ventricle chamber that mimics the exact size, shape and motion of a failing heart is desired to assist in flow visualization studies around inflow cannulae during VAD support. The aim of this study was therefore to design and construct a naturally shaped flexible left ventricle and evaluate its performance in a mock circulation loop. The ventricle shape was constructed by the use of CT images taken from a patient experiencing cardiomyopathic heart failure and used to create a 3D image and subsequent mould to produce a silicone ventricle. Different cardiac conditions were successfully simulated to validate the ventricle performance, including rest, left heart failure and VAD support.
- ventricular assist device
- mock circulation loop
- silicone ventricle
Gregory, S., Timms, D., Pearcy, M. J., & Tansley, G. D. (2009). A naturally shaped silicone ventricle evaluated in a mock circulation loop: a preliminary study. Journal of Medical Engineering and Technology, 33(3), 185-191. https://doi.org/10.1080/03091900802184072