TY - JOUR
T1 - A naturally shaped silicone ventricle evaluated in a mock circulation loop: a preliminary study
AU - Gregory, S.
AU - Timms, D.
AU - Pearcy, M.J.
AU - Tansley, Geoff D.
PY - 2009/4
Y1 - 2009/4
N2 - Mock circulation loops are used to evaluate the performance of cardiac assist devices prior to animal and clinical testing. A compressible, translucent silicone ventricle chamber that mimics the exact size, shape and motion of a failing heart is desired to assist in flow visualization studies around inflow cannulae during VAD support. The aim of this study was therefore to design and construct a naturally shaped flexible left ventricle and evaluate its performance in a mock circulation loop. The ventricle shape was constructed by the use of CT images taken from a patient experiencing cardiomyopathic heart failure and used to create a 3D image and subsequent mould to produce a silicone ventricle. Different cardiac conditions were successfully simulated to validate the ventricle performance, including rest, left heart failure and VAD support.
AB - Mock circulation loops are used to evaluate the performance of cardiac assist devices prior to animal and clinical testing. A compressible, translucent silicone ventricle chamber that mimics the exact size, shape and motion of a failing heart is desired to assist in flow visualization studies around inflow cannulae during VAD support. The aim of this study was therefore to design and construct a naturally shaped flexible left ventricle and evaluate its performance in a mock circulation loop. The ventricle shape was constructed by the use of CT images taken from a patient experiencing cardiomyopathic heart failure and used to create a 3D image and subsequent mould to produce a silicone ventricle. Different cardiac conditions were successfully simulated to validate the ventricle performance, including rest, left heart failure and VAD support.
KW - ventricular assist device
KW - mock circulation loop
KW - silicone ventricle
UR - http://www.scopus.com/inward/record.url?scp=67651154192&partnerID=8YFLogxK
UR - http://informahealthcare.com/doi/full/10.1080/03091900802184072
U2 - 10.1080/03091900802184072
DO - 10.1080/03091900802184072
M3 - Article
SN - 0309-1902
VL - 33
SP - 185
EP - 191
JO - Journal of Medical Engineering and Technology
JF - Journal of Medical Engineering and Technology
IS - 3
ER -