Chronotherapeutic delivery system for treating primary open-angle glaucoma, comprising a delivery system incorporating pharmaceutical products for delivery to an eye in the treatment of primary open-angle glaucoma (POAG), comprising: (a) a biocompatible erodible material incorporating a therapeutically-effective amount of a prostaglandin analogue, and (b) a reservoir containing a therapeutically-effective amount of a beta-blocker, whereby, when the delivery system is placed in the eye the prostaglandin analogue is delivered gradually as the erodible material is eroded, and the beta-blocker is delivered rapidly when at least a predetermined portion of the erodible material has been eroded.
|Patent number||P715802EP/1196/ US 2009/0155338 A1|
|Publication status||Published - 18 Jun 2009|
Gherghel, D., & Conway, B. (2009). A novel chronotherapeutic system for the treatment of primary open-angle glaucoma. (Patent No. P715802EP/1196/ US 2009/0155338 A1). http://www.patentsencyclopedia.com/app/20090155338