A specific and rapid neural signature for parental instinct

Morten L. Kringelbach, Annukka Lehtonen, Sarah Squire, Allison G. Harvey, Michelle G. Craske, Ian E. Holliday, Alexander L. Green, Tipu Z. Aziz, Peter C. Hansen, Piers L. Cornelissen, Alan Stein

Research output: Contribution to journalArticle

Abstract

Darwin originally pointed out that there is something about infants which prompts adults to respond to and care for them, in order to increase individual fitness, i.e. reproductive success, via increased survivorship of one's own offspring. Lorenz proposed that it is the specific structure of the infant face that serves to elicit these parental responses, but the biological basis for this remains elusive. Here, we investigated whether adults show specific brain responses to unfamiliar infant faces compared to adult faces, where the infant and adult faces had been carefully matched across the two groups for emotional valence and arousal, as well as size and luminosity. The faces also matched closely in terms of attractiveness. Using magnetoencephalography (MEG) in adults, we found that highly specific brain activity occurred within a seventh of a second in response to unfamiliar infant faces but not to adult faces. This activity occurred in the medial orbitofrontal cortex (mOFC), an area implicated in reward behaviour, suggesting for the first time a neural basis for this vital evolutionary process. We found a peak in activity first in mOFC and then in the right fusiform face area (FFA). In mOFC the first significant peak (p<0.001) in differences in power between infant and adult faces was found at around 130 ms in the 10-15 Hz band. These early differences were not found in the FFA. In contrast, differences in power were found later, at around 165 ms, in a different band (20-25 Hz) in the right FFA, suggesting a feedback effect from mOFC. These findings provide evidence in humans of a potential brain basis for the "innate releasing mechanisms" described by Lorenz for affection and nurturing of young infants. This has potentially important clinical applications in relation to postnatal depression, and could provide opportunities for early identification of families at risk.
Original languageEnglish
Article numbere1664
Number of pages7
JournalPLoS ONE
Volume3
Issue number2
DOIs
Publication statusPublished - 27 Feb 2008

Fingerprint

Instinct
Brain
Magnetoencephalography
Prefrontal Cortex
Luminance
Feedback
brain
Genetic Fitness
Postpartum Depression
Arousal
Reward

Bibliographical note

© 2008 Kringelbach et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits
unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Keywords

  • Darwin
  • infants
  • care
  • Lorenz
  • infant face
  • parental responses
  • brain responses
  • emotional valence
  • arousal

Cite this

Kringelbach, M. L., Lehtonen, A., Squire, S., Harvey, A. G., Craske, M. G., Holliday, I. E., ... Stein, A. (2008). A specific and rapid neural signature for parental instinct. PLoS ONE, 3(2), [e1664]. https://doi.org/10.1371/journal.pone.0001664
Kringelbach, Morten L. ; Lehtonen, Annukka ; Squire, Sarah ; Harvey, Allison G. ; Craske, Michelle G. ; Holliday, Ian E. ; Green, Alexander L. ; Aziz, Tipu Z. ; Hansen, Peter C. ; Cornelissen, Piers L. ; Stein, Alan. / A specific and rapid neural signature for parental instinct. In: PLoS ONE. 2008 ; Vol. 3, No. 2.
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Kringelbach, ML, Lehtonen, A, Squire, S, Harvey, AG, Craske, MG, Holliday, IE, Green, AL, Aziz, TZ, Hansen, PC, Cornelissen, PL & Stein, A 2008, 'A specific and rapid neural signature for parental instinct', PLoS ONE, vol. 3, no. 2, e1664. https://doi.org/10.1371/journal.pone.0001664

A specific and rapid neural signature for parental instinct. / Kringelbach, Morten L.; Lehtonen, Annukka; Squire, Sarah; Harvey, Allison G.; Craske, Michelle G.; Holliday, Ian E.; Green, Alexander L.; Aziz, Tipu Z.; Hansen, Peter C.; Cornelissen, Piers L.; Stein, Alan.

In: PLoS ONE, Vol. 3, No. 2, e1664, 27.02.2008.

Research output: Contribution to journalArticle

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Kringelbach ML, Lehtonen A, Squire S, Harvey AG, Craske MG, Holliday IE et al. A specific and rapid neural signature for parental instinct. PLoS ONE. 2008 Feb 27;3(2). e1664. https://doi.org/10.1371/journal.pone.0001664