Altered blood vessel responses in the eye and finger in coronary artery disease

Rebekka Heitmar, Robert P Cubbidge, Gregory Y.H. Lip, Doina Gherghel, Andrew D. Blann

Research output: Contribution to journalArticlepeer-review


Cardiac function, such as heart rate variability, is abnormal in coronary artery disease, but its relation with the function of ocular and nail-fold blood vessels is unknown. The hypothesis was that there is abnormal retinal and peripheral microvascular endothelial function compared with large blood vessel and cardiac function. Twenty-four patients with coronary artery disease (CAD) and 30 healthy, age- and sex-matched control subjects were enrolled in the study.
Original languageEnglish
Pages (from-to)6199-6205
Number of pages7
JournalInvestigative Ophthalmology and Visual Science
Issue number9
Early online date7 Apr 2011
Publication statusPublished - 3 Aug 2011


  • blood flow velocity
  • blood pressure
  • case-control studies
  • ciliary arteries
  • coronary artery disease
  • e-selectin
  • electrocardiography
  • enzyme-linked immunosorbent assay
  • female
  • fingers
  • heart rate
  • humans
  • intraocular pressure
  • male
  • middle aged
  • ophthalmic artery
  • retinal artery
  • supine position
  • von Willebrand factor


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