An aqueous extract of Fagonia cretica induces DNA damage, cell cycle arrest and apoptosis in breast cancer cells via FOXO3a and p53 expression

Medicine & Life Sciences

• Annexin A5 28%
• Apoptosis 46%
• Breast 19%
• Breast Neoplasms 48%
• Cell Cycle 20%
• Cell Cycle Checkpoints 74%
• Cell Cycle Resting Phase 30%
• Cell Death 19%
• Cell Line 30%
• Cell Proliferation 16%
• Cell Survival 38%
• Cyclin A 33%
• DNA Damage 66%
• Double-Stranded DNA Breaks 29%
• Epithelial Cells 18%
• G1 Phase 26%
• Growth 25%
• Herbal Teas 40%
• MCF-7 Cells 27%
• Neoplasms 16%
• Pharmaceutical Preparations 10%
• Propidium 29%
• Proteins 9%
• Small Interfering RNA 21%

Agriculture & Biology

• antineoplastic agents 22%
• apoptosis 70%
• breast neoplasms 87%
• breasts 8%
• cell cycle 8%
• cell cycle checkpoints 100%
• cell lines 14%
• cell proliferation 8%
• cell viability 17%
• cells 12%
• cyclins 11%
• cytotoxicity 8%
• death 7%
• DNA 4%
• DNA damage 74%
• dosage 4%
• epithelial cells 8%
• extracts 40%
• herbal tea 13%
• interphase 9%
• methodology 2%
• mutants 5%
• neoplasm cells 70%
• propidium 11%
• protein synthesis 7%
• small interfering RNA 11%
• transcription (genetics) 7%
• water 31%

Chemistry

• Antineoplastic Agent 67%
• Cell Viability 75%
• Flow 24%
• Propidium Iodide 52%
• Protein 15%
• Silencing RNA 49%
• Time 13%