An astrocyte bridge from synapse to blood flow

Rheinallt Parri; Vincenzo Crunelli

doi:10.1038/nn0103-5

An astrocyte bridge from synapse to blood flow

Rheinallt Parri
, Vincenzo Crunelli

Research output: Contribution to journal › Letter, comment/opinion or interview › peer-review

68 Citations (Scopus)

Abstract

Neural activity locally Increases cerebral blood flow to deliver oxygen to working neurons. A new paper shows that astrocytes can detect activity at glutamatergic synapses via calcium changes In astrocytic endfeet and directly couple It to blood flow in vitro and In vivo.

Original language	English
Pages (from-to)	5-6
Number of pages	2
Journal	Nature Neuroscience
Volume	6
Issue number	1
DOIs	https://doi.org/10.1038/nn0103-5
Publication status	Published - 2003

Keywords

Animals
Astrocytes
Brain
Cerebrovascular Circulation
Energy Metabolism
Glutamic Acid
Humans
Microcirculation
Presynaptic Terminals
Signal Transduction
Synaptic Transmission
Vasodilation

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10.1038/nn0103-5

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title = "An astrocyte bridge from synapse to blood flow",

abstract = "Neural activity locally Increases cerebral blood flow to deliver oxygen to working neurons. A new paper shows that astrocytes can detect activity at glutamatergic synapses via calcium changes In astrocytic endfeet and directly couple It to blood flow in vitro and In vivo.",

keywords = "Animals, Astrocytes, Brain, Cerebrovascular Circulation, Energy Metabolism, Glutamic Acid, Humans, Microcirculation, Presynaptic Terminals, Signal Transduction, Synaptic Transmission, Vasodilation",

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AU - Crunelli, Vincenzo

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KW - Animals

KW - Astrocytes

KW - Brain

KW - Cerebrovascular Circulation

KW - Energy Metabolism

KW - Glutamic Acid

KW - Humans

KW - Microcirculation

KW - Presynaptic Terminals

KW - Signal Transduction

KW - Synaptic Transmission

KW - Vasodilation

UR - https://www.nature.com/articles/nn0103-5

U2 - 10.1038/nn0103-5

DO - 10.1038/nn0103-5

M3 - Letter, comment/opinion or interview

C2 - 12494240

SN - 1097-6256

VL - 6

SP - 5

EP - 6

JO - Nature Neuroscience

JF - Nature Neuroscience

IS - 1

ER -

An astrocyte bridge from synapse to blood flow

Abstract

Keywords

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