TY - JOUR
T1 - Analysis of skin blood microflow oscillations in patients with rheumatic diseases
AU - Mizeva, Irina
AU - Makovik, Irina
AU - Dunaev, Andrey
AU - Krupatkin, Alexander
AU - Meglinski, Igor
N1 - © 2017 Society of Photo-Optical Instrumentation
Engineers (SPIE)
PY - 2017/7/13
Y1 - 2017/7/13
N2 - Laser Doppler flowmetry (LDF) has been applied for the assessment of variation in blood microflows in patients with rheumatic diseases and healthy volunteers. Oscillations of peripheral blood microcirculation observed by LDF have been analyzed utilizing a wavelet transform. A higher amplitude of blood microflow oscillations has been observed in a high frequency band (over 0.1 Hz) in patients with rheumatic diseases. Oscillations in the high frequency band decreased in healthy volunteers in response to the cold pressor test, whereas lower frequency pulsations prevailed in patients with rheumatic diseases. A higher perfusion rate at normal conditions was observed in patients, and a weaker response to cold stimulation was observed in healthy volunteers. Analysis of blood microflow oscillations has a high potential for evaluation of mechanisms of blood flow regulation and diagnosis of vascular abnormalities associated with rheumatic diseases.
AB - Laser Doppler flowmetry (LDF) has been applied for the assessment of variation in blood microflows in patients with rheumatic diseases and healthy volunteers. Oscillations of peripheral blood microcirculation observed by LDF have been analyzed utilizing a wavelet transform. A higher amplitude of blood microflow oscillations has been observed in a high frequency band (over 0.1 Hz) in patients with rheumatic diseases. Oscillations in the high frequency band decreased in healthy volunteers in response to the cold pressor test, whereas lower frequency pulsations prevailed in patients with rheumatic diseases. A higher perfusion rate at normal conditions was observed in patients, and a weaker response to cold stimulation was observed in healthy volunteers. Analysis of blood microflow oscillations has a high potential for evaluation of mechanisms of blood flow regulation and diagnosis of vascular abnormalities associated with rheumatic diseases.
KW - blood microflows
KW - laser Doppler flowmetry
KW - oscillations
KW - peripheral blood circulation
KW - rheumatic
KW - wavelet transfer
UR - http://www.scopus.com/inward/record.url?scp=85024473030&partnerID=8YFLogxK
UR - https://www.spiedigitallibrary.org/journals/Journal-of-Biomedical-Optics/volume-22/issue-07/070501/Analysis-of-skin-blood-microflow-oscillations-in-patients-with-rheumatic/10.1117/1.JBO.22.7.070501.full
U2 - 10.1117/1.JBO.22.7.070501
DO - 10.1117/1.JBO.22.7.070501
M3 - Article
C2 - 28703257
AN - SCOPUS:85024473030
SN - 1083-3668
VL - 22
JO - Journal of Biomedical Optics
JF - Journal of Biomedical Optics
IS - 7
M1 - 070501
ER -