Abstract
Aims: Angioplasty has changed the management of acute coronary syndromes (ACS). However,
in patients with chronic anaemia the evidence for angioplasty in ACS is less well known. We
sought to investigate the role of angioplasty in patients with anaemia presenting with ACS, and
how it affected mortality.
Method: Anonymous information on patients with ACS, attending a large multi-ethnic general
hospital in Manchester, United Kingdom in the period 2000-2013 was obtained from the local
health authority computerised hospital activity analysis register using ICD-10 and OPCS coding
systems according to the ACALM protocol.
Results: Out of 25294 patients, 1551(6.1%) patients had Anaemia as defined by national
standards. Of these, 89(5.7%) patients underwent angioplasty with mean age 65.0 years and
were significantly younger than patients who did not undergo angioplasty. Patients who did not
undergo angioplasty had higher prevalence of Ischaemic Stroke(6.2% vs 1.1%), Heart
Failure(36.7% vs 11.2%) and Chronic Kidney Disease(18.7% vs 4.5%), whilst angioplasty
patients had higher prevalence of previous ACS (27.2% vs 36.0%) and peripheral vascular
disease(6.8% vs 7.9%). Multi-nominal logistic regression analysis revealed Heart
Failure(RR2.16), Ischaemic Stroke(RR3.67) and Chronic Kidney Disease(RR1.39) as significant
predictors of mortality in this patient group. Angioplasty(RR7.81) and previous ACS(RR1.88)
conferred mortality improvement in this patient group.
in patients with chronic anaemia the evidence for angioplasty in ACS is less well known. We
sought to investigate the role of angioplasty in patients with anaemia presenting with ACS, and
how it affected mortality.
Method: Anonymous information on patients with ACS, attending a large multi-ethnic general
hospital in Manchester, United Kingdom in the period 2000-2013 was obtained from the local
health authority computerised hospital activity analysis register using ICD-10 and OPCS coding
systems according to the ACALM protocol.
Results: Out of 25294 patients, 1551(6.1%) patients had Anaemia as defined by national
standards. Of these, 89(5.7%) patients underwent angioplasty with mean age 65.0 years and
were significantly younger than patients who did not undergo angioplasty. Patients who did not
undergo angioplasty had higher prevalence of Ischaemic Stroke(6.2% vs 1.1%), Heart
Failure(36.7% vs 11.2%) and Chronic Kidney Disease(18.7% vs 4.5%), whilst angioplasty
patients had higher prevalence of previous ACS (27.2% vs 36.0%) and peripheral vascular
disease(6.8% vs 7.9%). Multi-nominal logistic regression analysis revealed Heart
Failure(RR2.16), Ischaemic Stroke(RR3.67) and Chronic Kidney Disease(RR1.39) as significant
predictors of mortality in this patient group. Angioplasty(RR7.81) and previous ACS(RR1.88)
conferred mortality improvement in this patient group.
| Original language | English |
|---|---|
| Article number | 358 |
| Pages (from-to) | 278 |
| Number of pages | 1 |
| Journal | Cardiology |
| Volume | 132 |
| Issue number | supp 1 |
| DOIs | |
| Publication status | Published - 29 Nov 2015 |