Deficiencia de vitamina D: ¿Factor de riesgo de síndrome metabólico? Vitamina D y síndrome metabólico

Translated title of the contribution: Association between vitamin D deficiency and metabolic syndrome

Research output: Contribution to journalArticle

Abstract

Vitamin D has an essential role in calcium metabolism and bone health. Vitamin
D3 or cholecalciferol is synthesized from 7-dehydrocholesterol or provitamin D3, by sunlight ultraviolet radiation to the skin. 7-dehydrocholesterol is subsequently hydroxylated in the liver and then in the kidney to produce 1,25-(OH)2D3, the active metabolite that binds to specific receptors (VDR) in target tissues, mainly bone and intestine. Other tissues, such as the immune and cardiovascular system, have also VDR. Vitamin D deficiency can induce rickets in children and osteomalacia and osteoporosis in adults. A possible inverse association between vitamin D levels and the prevalence of metabolic syndrome has been proposed. Vitamin D deficiency increases the risk of type 1 diabetes, insulin resistance, and hypertension, key components of this syndrome. However, other studies have not confirmed this association. Further clinical and experimental studies are needed to ascertain the role of vitamin D in metabolic syndrome.
Original languageSpanish
Pages (from-to)1312-1318
Number of pages7
JournalRevista Medica de Chile
Volume138
Issue number10
DOIs
Publication statusPublished - 2010

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Vitamin D Deficiency
Vitamin D
Bone and Bones
Osteomalacia
Rickets
Cholecalciferol
Sunlight
Cardiovascular System
Type 1 Diabetes Mellitus
Osteoporosis
Intestines
Insulin Resistance
Immune System
Radiation
Hypertension
Calcium
Kidney
Skin
Liver
Health

Bibliographical note

Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons

Cite this

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title = "Deficiencia de vitamina D: ¿Factor de riesgo de s{\'i}ndrome metab{\'o}lico?: Vitamina D y s{\'i}ndrome metab{\'o}lico",
abstract = "Vitamin D has an essential role in calcium metabolism and bone health. VitaminD3 or cholecalciferol is synthesized from 7-dehydrocholesterol or provitamin D3, by sunlight ultraviolet radiation to the skin. 7-dehydrocholesterol is subsequently hydroxylated in the liver and then in the kidney to produce 1,25-(OH)2D3, the active metabolite that binds to specific receptors (VDR) in target tissues, mainly bone and intestine. Other tissues, such as the immune and cardiovascular system, have also VDR. Vitamin D deficiency can induce rickets in children and osteomalacia and osteoporosis in adults. A possible inverse association between vitamin D levels and the prevalence of metabolic syndrome has been proposed. Vitamin D deficiency increases the risk of type 1 diabetes, insulin resistance, and hypertension, key components of this syndrome. However, other studies have not confirmed this association. Further clinical and experimental studies are needed to ascertain the role of vitamin D in metabolic syndrome.",
author = "{Sanchez Aranguren}, Lissette",
note = "Todo el contenido de esta revista, excepto d{\'o}nde est{\'a} identificado, est{\'a} bajo una Licencia Creative Commons",
year = "2010",
doi = "10.4067/S0034-98872010001100017",
language = "Spanish",
volume = "138",
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number = "10",

}

Deficiencia de vitamina D: ¿Factor de riesgo de síndrome metabólico? Vitamina D y síndrome metabólico. / Sanchez Aranguren , Lissette.

In: Revista Medica de Chile, Vol. 138, No. 10, 2010, p. 1312-1318.

Research output: Contribution to journalArticle

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T2 - Vitamina D y síndrome metabólico

AU - Sanchez Aranguren , Lissette

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PY - 2010

Y1 - 2010

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