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Association of Reduction in Continuity of Care During COVID‐19 Pandemic With Cardiovascular Diseases, Kidney Failure and All‐Cause Mortality for People With Diabetes: A Cohort Study in Hong Kong

  • Yuk Kam Yau
  • , Meijiao Li
  • , Jianchao Quan
  • , Karen Ann Grépin
  • , Gary Kui Kai Lau
  • , Ivy Lynn Mak
  • , Chak Sing Lau
  • , Ian Chi Kei Wong
  • , David Vai Kiong Chao
  • , Welchie Wai Kit Ko
  • , Cindy Lo Kuen Lam
  • , Eric Yuk Fai Wan
  • Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Aston Pharmacy School, Aston University, Birmingham, United Kingdom.
  • Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Department of Family Medicine and Primary Health Care United Christian Hospital, Kowloon East Cluster, Hospital Authority Hong Kong Special Administrative Region China
  • Department of Family Medicine and Primary Healthcare Hong Kong West Cluster, Hospital Authority Hong Kong Special Administrative Region of China China
  • Department of Family Medicine, the University of Hong Kong Shenzhen Hospital, The University of Hong Kong, Hong Kong SAR, China.
  • The Institute of Cardiovascular Science and Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Continuity of care, a critical component of high-quality primary care, was interrupted in people with diabetes mellitus during the COVID-19 pandemic in Hong Kong. Research on whether reduced continuity of care was associated with higher complications and mortality risks is lacking.

Methods: This retrospective cohort study included 123 403 eligible adult patients with diabetes. Continuity of care was assessed by the usual provider continuity index (UPCI), calculated as the proportion of attendances to the patients' most visited clinic during both pre-outbreak period (August 2017–December 2019) and outbreak period (January 2020–May 2022). Patients were followed from 1 June 2022 until the outcomes of interest or June 2024. Cox regression was applied to evaluate the association between reduced continuity of care and risks of incident cardiovascular diseases (CVD), kidney failure and all-cause mortality.

Results: Greater reductions in UPCI were associated with higher risks of CVD; the hazard ratios (HR, 95% CI) for 10%–20% reduction were 1.05 (0.97, 1.14), HR = 1.33 (1.14, 1.56) for 20%–30% reduction, and HR = 1.30 (1.14, 1.48) for 30% reduction when compared to patients experiencing ≤ 10% reduction in UPCI. Similar patterns were found for CVD subtypes, including coronary heart disease and heart failure. Reductions of 20%–30% and > 30.1% in UPCI were associated with higher kidney failure risks.

Conclusion: Greater impairment in continuity of care was associated with increased incidences of CVD in diabetic patients. Our results emphasize the need for health policies to have contingency plans for maintaining continuity of primary care for patients with DM in future public health crises.
Original languageEnglish
Number of pages9
JournalDiabetes, Obesity and Metabolism
Early online date15 Jun 2026
DOIs
Publication statusE-pub ahead of print - 15 Jun 2026

Bibliographical note

© 2026 The Author(s). Diabetes, Obesity and Metabolism published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Data Access Statement

Data will not be made available to others because the data custodians have not given permission.

Funding

This work was funded by the Health and Medical Research Fund, Health Bureau, Government of Hong Kong Special Administrative Region (grant no: COVID19F08).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • cardiovascular disease
  • continuity of care
  • death
  • kidney failure
  • type 2 disease

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