Astrocytes target presynaptic NMDA receptors to give synapses a boost

Rheinallt Parri*, Vincenzo Crunelli

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Astrocytes modulate synaptic strength. This effect occurs, reports a new paper, because ATP-dependent vesicular release of astrocytic glutamate acts on presynaptic neuronal NMDA receptors to increase synaptic efficacy. © 2007 Nature Publishing Group.

Original languageEnglish
Pages (from-to)271-273
Number of pages3
JournalNature Neuroscience
Volume10
Issue number3
DOIs
Publication statusPublished - Mar 2007

Keywords

  • synapses
  • astrocytes
  • presynaptic terminals
  • N-Methyl-D-Aspartate receptors

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