Basic implications on three pathways associated with SARS-CoV-2

Jong Hoon Lee, Consolato Sergi, Richard E. Kast, Badar A. Kanwar, Jean Bourbeau, Sangsuk Oh, Mun-Gi Sohn, Chul Joong Lee, Michael D. Coleman

Research output: Contribution to journalArticlepeer-review

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts between the host and virus and govern induction, resulting in multiorgan impacts. Its pathophysiology involves the followings: 1) the angiotensin-converting enzyme (ACE2) and Toll-like receptor (TLR) pathways: 2) the neuropilin (NRP) pathway: 3) the spike protein pathway. Therefore, it is necessary to block the pathological course with modulating innate lymphoid cells against diverse corona variants in the future.
Original languageEnglish
Article number100766
Number of pages11
JournalBiomedical Journal
Early online date14 Jul 2024
DOIs
Publication statusE-pub ahead of print - 14 Jul 2024

Bibliographical note

Copyright © 2024 The Authors. Published by Elsevier B.V. on behalf of Chang Gung University. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Keywords

  • COVID-19
  • TLR
  • SARS-CoV-2
  • ACE2
  • Spike protein

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